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Showing 1 to 12 of 5081 entries
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Metformin prescription status and abdominal aortic aneurysm disease progression in the US veteran population

veteran

Itoga NK, Ho TV.
GSID: QDFP2fQQjkoJ
NK Itoga, KA Rothenberg, P Suarez, TV Ho… - Journal of vascular …, 2019 - Elsevier

Background Identification of a safe and effective medical therapy for abdominal aortic aneurysm (AAA) disease remains a significant unmet medical need. Recent small cohort studies …

The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial

program design

[No authors listed]
GSID: bwq1zDsOBVYJ
…, Diabetes Prevention Program Research … - Annals of internal …, 2005 - acpjournals.org

… participated in the design of the study and in the reporting of the results. Although additional funding was provided by a variety of other sources, as listed in the acknowledgments, these sources had no role in the design...

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

program design

Knowler WC.
GSID: kehJIfRE68kJ
WC Knowler, E Barrett-Connor, SE Fowler… - 2002 - jdc.jefferson.edu

BACKGROUND: Type 2 diabetes affects approximately 8 percent of adults in the United States. Some risk factors--elevated plasma glucose concentrations in the fasting state and …

Effects of withdrawal from metformin on the development of diabetes in the diabetes prevention program

program design

[No authors listed]
GSID: trm70WgQYjcJ
Diabetes Prevention Program Research Group - Diabetes Care, 2003 - Am Diabetes Assoc

… We thank the thousands of volunteers in this program for their devotion to the goal of diabetes prevention. LifeScan, Health O Meter, Hoechst Marion Roussel, Lipha Pharmaceuticals, Merck-Medco Managed Care, Merck and Co., Nike Sports Marketing, Slim Fast...

Evaluation of Vitamin B12 Monitoring in a Veteran Population on Long-Term, High-Dose Metformin Therapy

veteran

[No authors listed]
GSID: onkarH_EF58J
SA Pierce, AH Chung, KK Black - Annals of …, 2012 - journals.sagepub.com

BACKGROUND: Metformin can result in vitamin B 12 deficiency, potentially leading to complications such as neuropathy. Annual monitoring of vitamin B 12 has been suggested; …

Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program

program design

[No authors listed]
GSID: F1JFxbSeB78J
Diabetes Prevention Program Research Group - Diabetes care, 2005 - Am Diabetes Assoc

OBJECTIVE—The Diabetes Prevention Program demonstrated the ability to delay or prevent type 2 diabetes in participants with impaired glucose tolerance (IGT). Participants with IGT …

Metformin-associated lactic acidosis.

Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association

Briggs D.
PMID: 25185923
Emerg Nurse. 2014 Sep;22(5):20-5. doi: 10.7748/en.22.5.20.e1332.

This article discusses the case of a 68-year-old emergency department patient with hypoglycaemia, hypotension, unconsciousness and a severe metabolic acidosis. It transpired that she had type 2 diabetes mellitus, which she managed with metformin, and ED staff thought initially...

A crossover study of the combination therapy of metformin and exenatide or biphasic insulin aspart 30 in overweight or obese patients newly diagnosed with type 2 diabetes mellitus.

Experimental and therapeutic medicine

Quan H, Zhang H, Wei W, Fang T, Chen D, Chen K.
PMID: 28912879
Exp Ther Med. 2017 Oct;14(4):3279-3287. doi: 10.3892/etm.2017.4863. Epub 2017 Aug 02.

The aim of the present study was to explore the effects of various combinations of exenatide, metformin (MET) and biphasic insulin aspart 30 (BIA30) on type 2 diabetes mellitus (T2DM). Two hundred overweight or obese patients newly diagnosed with...

Diabetes mellitus caused by secondary hemochromatosis after multiple blood transfusions in 2 patients with severe aplastic anemia.

Annals of pediatric endocrinology & metabolism

Kim HJ, Kim YM, Kang E, Lee BH, Choi JH, Yoo HW.
PMID: 28443261
Ann Pediatr Endocrinol Metab. 2017 Mar;22(1):60-64. doi: 10.6065/apem.2017.22.1.60. Epub 2017 Mar 31.

Hemochromatosis is an inherited or secondary disorder caused by excessive iron storage leading to multiple organ damage. We describe 2 patients with diabetes mellitus caused by hemochromatosis secondary to multiple blood transfusions due to severe aplastic anemia. Subject 1,...

Comparison of hemoglobin A1c goal achievement with the addition of pioglitazone to maximal/highest tolerated doses of sulfonylurea and metformin combination therapy.

Journal of drug assessment

McFarland MS, Huddleston L, Tammareddi K, McKenzie M, Bean J.
PMID: 27536426
J Drug Assess. 2012 Jun 29;1(1):34-9. doi: 10.3109/21556660.2012.707996. eCollection 2012.

OBJECTIVES: It has been proposed that the combination of thiazolidinedione (TZD) therapy to metformin and sulfonylurea is beneficial due to each medication having a unique mechanism of action. Within the Veterans Affairs Hospital, specific criteria of use define when...

Comparison of Pioglitazone and Metformin Efficacy against Glucocorticoid Induced Atherosclerosis and Hepatic Steatosis in Insulin Resistant Rats.

Journal of clinical and diagnostic research : JCDR

Nayak IMN, Narendar K, M PA, Jamadar MG, Kumar VH.
PMID: 28892924
J Clin Diagn Res. 2017 Jul;11(7):FC06-FC10. doi: 10.7860/JCDR/2017/28418.10193. Epub 2017 Jul 01.

INTRODUCTION: Insulin Resistance is a major cause of Atherosclerosis (AS) and Non Alcoholic Fatty Liver Disease (NAFLD). These lipid alterations in blood vessels and liver may progress to cardiovascular abnormalities and cirrhosis respectively. Drugs like pioglitazone (PIO) and metformin...

Bio-enhancing Effect of Piperine with Metformin on Lowering Blood Glucose Level in Alloxan Induced Diabetic Mice.

Pharmacognosy research

Atal S, Atal S, Vyas S, Phadnis P.
PMID: 26941537
Pharmacognosy Res. 2016 Jan-Mar;8(1):56-60. doi: 10.4103/0974-8490.171096.

BACKGROUND: Diabetes mellitus is the most rampant metabolic pandemic of the 21(st) century. Piperine, the chief alkaloid of Piper nigrum (black pepper) is widely used in alternative and complementary therapies has been extensively studied for its bio-enhancing property.OBJECTIVE: To...

Showing 1 to 12 of 5081 entries