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Showing 1 to 12 of 67 entries
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Sensitive determination of mianserin and setiptiline in body fluids by gas chromatography with surface ionization detection (GC-SID).

Legal medicine (Tokyo, Japan)

Ishii A, Kurihara R, Kojima T, Sano T, Mizuno Y, Yamakawa Y, Katsumata Y.
PMID: 12935454
Leg Med (Tokyo). 2000 Aug;2(2):115-8. doi: 10.1016/s1344-6223(00)80035-8.

Tetracyclic antidepressants, mianserin and setiptiline, in human body fluids have been found measurable with high sensitivity by gas chromatography (GC) with surface ionization detection (SID). The compounds in human whole blood or urine samples were extracted by solid-phase extraction...

Carrier-mediated and carrier-independent release of serotonin from isolated central nerve endings.

Neurochemistry international

Maura G, Gemignani A, Versace P, Martire M, Raiteri M.
PMID: 20487871
Neurochem Int. 1982;4(4):219-24. doi: 10.1016/0197-0186(82)90057-2.

The release of serotonin elicited by Ca(2+)-dependent stimuli (depolarization, ionophore A23187) from rat brain synaptosomes previously labelled with the radioactive indoleamine was not affected by the presence of the serotonin carrier blocker chlorimipramine. In contrast, other releasing stimuli, such...

Progesterone stimulation of in vitro GnRH release from the hypothalamus of the estrogen-primed, ovariectomized rat: serotoninergic role.

Neurochemistry international

King TS, Kang IS.
PMID: 20501305
Neurochem Int. 1988;13(4):469-74. doi: 10.1016/0197-0186(88)90076-9.

The ability of ovarian steroids to affect luteinizing hormone secretion is closely related to the influence of these steroids on the activities of several neurotransmitter systems within specific areas of the hypothalamus and associated brain areas. The purpose of...

Ketanserin and mianserin treatment reverses hyperactivity in neonatally dopamine-lesioned rats.

Journal of psychopharmacology (Oxford, England)

Luthman J, Fredriksson A, Plaznik A, Archer T.
PMID: 22282852
J Psychopharmacol. 1991 Jan;5(4):418-25. doi: 10.1177/026988119100500437.

Selective brain dopamine (DA) depletions in rats, induced by neonatal intracisternal administration of 6-hydroxydopamine (6-OHDA; 75 μg), caused spontaneous hyperactivity at the adult stage as measured using determinations of locomotion, rearing and total activity. Treatment with ketanserin (0.5 or...

In vivo [(3)H]ketanserin binding: effect of modifying synaptic serotonin levels.

Neurochemistry international

Assie MB, Charveron M, Briley M.
PMID: 20501207
Neurochem Int. 1988;12(1):85-9. doi: 10.1016/0197-0186(88)90152-0.

Most antidepressant therapies aim to increase the synaptic concentration of one or more of the monoamines. Synaptic monoamine levels are, however, extremely difficult to measure. In order to estimate synaptic levels of serotonin, an indirect method has been used....

Solitary thyroid metastasis from colon cancer: a rare case report.

Ecancermedicalscience

Nicosia L, Alessi S, Proh M, Grosso E, Ansarin M, Vingiani A, Pisa E, De Fiori E.
PMID: 28101139
Ecancermedicalscience. 2016 Nov 24;10:696. doi: 10.3332/ecancer.2016.696. eCollection 2016.

Malignant metastases to the thyroid are rare and are even rarer from a colorectal primary. As these metastases are often asymptomatic, they are usually discovered incidentally on imaging performed as follow-up for the primary tumour. In this report, we...

Antidepressant transfer into amniotic fluid, umbilical cord blood & breast milk: A systematic review & combined analysis.

Progress in neuro-psychopharmacology & biological psychiatry

Schoretsanitis G, Westin AA, Stingl JC, Deligiannidis KM, Paulzen M, Spigset O.
PMID: 33358964
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Apr 20;107:110228. doi: 10.1016/j.pnpbp.2020.110228. Epub 2021 Jan 02.

OBJECTIVE: Data regarding the ability of antidepressants to enter fetal, newborn and infant fluids have become gradually available, but mechanisms of antidepressant transfer remain poorly understood. Here we calculated penetration ratios in an array of matrices from combined samples...

Use of sedating medications around nursing home admission in Denmark.

Pharmacoepidemiology and drug safety

Pottegård A, Lundby C, Jarbøl DE, Larsen SP, Hoppe BC, Hoffmann H, Thompson W.
PMID: 34382278
Pharmacoepidemiol Drug Saf. 2021 Nov;30(11):1560-1565. doi: 10.1002/pds.5341. Epub 2021 Aug 22.

PURPOSE: To examine use of sedating medications around the time of nursing home admission in Denmark.METHODS: We conducted a register-based drug utilization study, describing patterns of commonly used medications with sedative effects leading up to and after nursing home...

Multiple high-affinity binding sites for.

The Journal of experimental biology

Winberg S, Nilsson G.
PMID: 9320352
J Exp Biol. 1996;199:2429-35.

Binding of [3H]serotonin (5-HT) to membranes prepared from Arctic charr brain homogenates was most consistent with a one-site model for [3H]5-HT binding, with KD and Bmax values of 5.7±0.3 nmol l-1 and 60.7±7.3 fmol mg-1 protein, respectively. Similarly, 5-HT...

Seasonal and circadian variations of behavioural response to antidepressants in the forced swimming test in rats.

Behavioural pharmacology

Borsini F, Lecci A, Stasi MA, Pessia M, Meli A.
PMID: 11175424
Behav Pharmacol. 1990;1(5):395-401.

In order to verify whether the variability reported to occur in the effectiveness of antidepressants in the forced swimming test (FST) was due to seasonal and/or circadian variations, the anti-immobility effect induced by several antidepressants was assessed in rats...

Allergy to chlorpromazine and valproic acid following carbamazepine hypersensitivity in a patient with an HLA-B*4601 allele.

Neuropsychiatric disease and treatment

Sakurada K, Kozaru T, Yamada K, Nibuya M, Nagata K, Suzuki E.
PMID: 29765217
Neuropsychiatr Dis Treat. 2018 May 04;14:1139-1142. doi: 10.2147/NDT.S162261. eCollection 2018.

A 73-year-old man, exhibiting psychomotor excitement after traumatic brain injury, developed allergic cutaneous eruptions and hepatic inflammation that did not resolve after the cessation of carbamazepine (CBZ). Fusing maculopapular erythema was observed in the face, neck, presternal region, and...

Interactions of antidepressants and ethanol on spontaneous locomotor activity and rotarod performance in NMRI and C57BL/6 mice.

Journal of psychopharmacology (Oxford, England)

Strömberg C.
PMID: 22155840
J Psychopharmacol. 1988 Jan;2(2):61-6. doi: 10.1177/026988118800200201.

In order to find appropriate doses for studying antidepressant-ethanol interaction in two mouse strains, spontaneous locomotor activity and rotarod performance were first studied in NMRI mice after amitriptyline 3-30 mg/kg, mianserin 3-30 mg/kg, nomifensine 1- 10 mg/kg, citalopram 3-100...

Showing 1 to 12 of 67 entries