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A Monoiodotyrosine Challenge Test in a Parkinson's Disease Model.

Acta naturae

Kim AR, Pavlova EN, Blokhin VE, Bogdanov VV, Ugrumov MV.
PMID: 34707902
Acta Naturae. 2021 Jul-Sep;13(3):106-109. doi: 10.32607/actanaturae.11399.

Early (preclinical) diagnosis of Parkinson's disease (PD) is a major challenge in modern neuroscience. The objective of this study was to experimentally evaluate a diagnostic challenge test with monoiodotyrosine (MIT), an endogenous inhibitor of tyrosine hydroxylase. Striatal dopamine was...

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Kim AR, Pavlova EN, Blokhin VE, et al. A Monoiodotyrosine Challenge Test in a Parkinson's Disease Model. Acta Naturae. 2021;13(3):106-109doi: 10.32607/actanaturae.11399.
Kim, A. R., Pavlova, E. N., Blokhin, V. E., Bogdanov, V. V., & Ugrumov, M. V. (2021). A Monoiodotyrosine Challenge Test in a Parkinson's Disease Model. Acta naturae, 13(3), 106-109. https://doi.org/10.32607/actanaturae.11399
Kim, A R, et al. "A Monoiodotyrosine Challenge Test in a Parkinson's Disease Model." Acta naturae vol. 13,3 (2021): 106-109. doi: https://doi.org/10.32607/actanaturae.11399
Kim AR, Pavlova EN, Blokhin VE, Bogdanov VV, Ugrumov MV. A Monoiodotyrosine Challenge Test in a Parkinson's Disease Model. Acta Naturae. 2021 Jul-Sep;13(3):106-109. doi: 10.32607/actanaturae.11399. PMID: 34707902; PMCID: PMC8526187.
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Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship.

Hematology, transfusion and cell therapy

Pedrosa AM, Leal LKAM, Lemes RPG.
PMID: 33051133
Hematol Transfus Cell Ther. 2021 Oct-Dec;43(4):468-475. doi: 10.1016/j.htct.2020.07.011. Epub 2020 Sep 30.

INTRODUCTION: Although the efficacy of hydroxyurea (HU) in inhibiting erythrocyte sickling has been well demonstrated, the action of this drug on human neutrophils and the mechanism by which it improves the manifestations of the disease have not been studied...

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Pedrosa AM, Leal LKAM, Lemes RPG. Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship. Hematol Transfus Cell Ther. 2020;43(4):468-475doi: 10.1016/j.htct.2020.07.011.
Pedrosa, A. M., Leal, L. K. A. M., & Lemes, R. P. G. (2021). Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship. Hematology, transfusion and cell therapy, 43(4), 468-475. https://doi.org/10.1016/j.htct.2020.07.011
Pedrosa, Alano Martins, et al. "Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship." Hematology, transfusion and cell therapy vol. 43,4 (2021): 468-475. doi: https://doi.org/10.1016/j.htct.2020.07.011
Pedrosa AM, Leal LKAM, Lemes RPG. Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship. Hematol Transfus Cell Ther. 2021 Oct-Dec;43(4):468-475. doi: 10.1016/j.htct.2020.07.011. Epub 2020 Sep 30. PMID: 33051133; PMCID: PMC8573033.
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Serum diiodotyrosine - a biomarker to differentiate destructive thyroiditis from Graves' disease.

European journal of endocrinology

Fujita N, Ono Y, Sano A, Kimata M, Oyama S, Hashimoto K, Sato I, Kudo M, Miyashiro Y, Fujikata A, Tanaka Y.
PMID: 34874894
Eur J Endocrinol. 2022 Jan 06;186(2):245-253. doi: 10.1530/EJE-21-0901.

OBJECTIVE: Conventional diagnostic methods are limited in their ability to differentiate destructive thyroiditis from Graves' disease. We hypothesised that serum diiodotyrosine (DIT) and monoiodotyrosine (MIT) levels could be biomarkers for differentiating destructive thyroiditis from Graves' disease.DESIGN: Patients with destructive...

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Fujita N, Ono Y, Sano A, et al. Serum diiodotyrosine - a biomarker to differentiate destructive thyroiditis from Graves' disease. Eur J Endocrinol. 2022;186(2):245-253doi: 10.1530/EJE-21-0901.
Fujita, N., Ono, Y., Sano, A., Kimata, M., Oyama, S., Hashimoto, K., Sato, I., Kudo, M., Miyashiro, Y., Fujikata, A., & Tanaka, Y. (2022). Serum diiodotyrosine - a biomarker to differentiate destructive thyroiditis from Graves' disease. European journal of endocrinology, 186(2), 245-253. https://doi.org/10.1530/EJE-21-0901
Fujita, Naoya, et al. "Serum diiodotyrosine - a biomarker to differentiate destructive thyroiditis from Graves' disease." European journal of endocrinology vol. 186,2 (2022): 245-253. doi: https://doi.org/10.1530/EJE-21-0901
Fujita N, Ono Y, Sano A, Kimata M, Oyama S, Hashimoto K, Sato I, Kudo M, Miyashiro Y, Fujikata A, Tanaka Y. Serum diiodotyrosine - a biomarker to differentiate destructive thyroiditis from Graves' disease. Eur J Endocrinol. 2022 Jan 06;186(2):245-253. doi: 10.1530/EJE-21-0901. PMID: 34874894.
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The structure of natively iodinated bovine thyroglobulin.

Acta crystallographica. Section D, Structural biology

Kim K, Kopylov M, Bobe D, Kelley K, Eng ET, Arvan P, Clarke OB.
PMID: 34726172
Acta Crystallogr D Struct Biol. 2021 Nov 01;77:1451-1459. doi: 10.1107/S2059798321010056. Epub 2021 Oct 29.

Thyroglobulin is a homodimeric glycoprotein that is essential for the generation of thyroid hormones in vertebrates. Upon secretion into the lumen of follicles in the thyroid gland, tyrosine residues within the protein become iodinated to produce monoiodotyrosine (MIT) and...

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Kim K, Kopylov M, Bobe D, et al. The structure of natively iodinated bovine thyroglobulin. Acta Crystallogr D Struct Biol. 2021;77:1451-1459doi: 10.1107/S2059798321010056.
Kim, K., Kopylov, M., Bobe, D., Kelley, K., Eng, E. T., Arvan, P., & Clarke, O. B. (2021). The structure of natively iodinated bovine thyroglobulin. Acta crystallographica. Section D, Structural biology, 771451-1459. https://doi.org/10.1107/S2059798321010056
Kim, Kookjoo, et al. "The structure of natively iodinated bovine thyroglobulin." Acta crystallographica. Section D, Structural biology vol. 77 (2021): 1451-1459. doi: https://doi.org/10.1107/S2059798321010056
Kim K, Kopylov M, Bobe D, Kelley K, Eng ET, Arvan P, Clarke OB. The structure of natively iodinated bovine thyroglobulin. Acta Crystallogr D Struct Biol. 2021 Nov 01;77:1451-1459. doi: 10.1107/S2059798321010056. Epub 2021 Oct 29. PMID: 34726172; PMCID: PMC8561740.
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Serum diiodotyrosine-a biomarker to differentiate destructive thyroiditis from Graves' disease.

European journal of endocrinology

Fujita N, Ono Y, Sano A, Kimata M, Oyama S, Hashimoto K, Sato I, Kudo M, Miyashiro Y, Fujikata A, Tanaka Y.
PMID: 34874894
Eur J Endocrinol. 2021 Dec 01; doi: 10.1530/EJE-21-0901. Epub 2021 Dec 01.

OBJECTIVE: Conventional diagnostic methods are limited in their ability to differentiate destructive thyroiditis from Graves' disease. We hypothesised that serum diiodotyrosine (DIT) and monoiodotyrosine (MIT) levels could be biomarkers for differentiating destructive thyroiditis from Graves' disease.DESIGN: Patients with destructive...

Cite
Fujita N, Ono Y, Sano A, et al. Serum diiodotyrosine-a biomarker to differentiate destructive thyroiditis from Graves' disease. Eur J Endocrinol. 2021;doi: 10.1530/EJE-21-0901.
Fujita, N., Ono, Y., Sano, A., Kimata, M., Oyama, S., Hashimoto, K., Sato, I., Kudo, M., Miyashiro, Y., Fujikata, A., & Tanaka, Y. (2021). Serum diiodotyrosine-a biomarker to differentiate destructive thyroiditis from Graves' disease. European journal of endocrinology, . https://doi.org/10.1530/EJE-21-0901
Fujita, Naoya, et al. "Serum diiodotyrosine-a biomarker to differentiate destructive thyroiditis from Graves' disease." European journal of endocrinology vol. (2021). doi: https://doi.org/10.1530/EJE-21-0901
Fujita N, Ono Y, Sano A, Kimata M, Oyama S, Hashimoto K, Sato I, Kudo M, Miyashiro Y, Fujikata A, Tanaka Y. Serum diiodotyrosine-a biomarker to differentiate destructive thyroiditis from Graves' disease. Eur J Endocrinol. 2021 Dec 01; doi: 10.1530/EJE-21-0901. Epub 2021 Dec 01. PMID: 34874894.
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Showing 1 to 5 of 5 entries