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Showing 1 to 8 of 8 entries
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bioRxiv : the preprint server for biology

Vo QN, Mahinthichaichan P, Shen J, Ellis CR.
PMID: 32839778
bioRxiv. 2020 Nov 25; doi: 10.1101/2020.08.16.253013.

In 2019, drug overdose has claimed over 70,000 lives in the United States. More than half of the deaths are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In recent years,...

Advances in the Physicochemical Profiling of Opioid Compounds of Therapeutic Interest.

ChemistryOpen

Mazák K, Noszál B, Hosztafi S.
PMID: 31312587
ChemistryOpen. 2019 Jul 04;8(7):879-887. doi: 10.1002/open.201900115. eCollection 2019 Jul.

This review focuses on recent developments in the physicochemical profiling of morphine and other opioids. The acid-base properties and lipophilicity of these compounds is discussed at the microscopic, species-specific level. Examples are provided where this type of information can...

THE ENZYMATIC DEACETYLATION OF HEROIN AND CLOSELY RELATED MORPHINE DERIVATIVES BY BLOOD SERUM.

Science (New York, N.Y.)

Wright CI.
PMID: 17814312
Science. 1940 Sep 13;92(2385):244-5. doi: 10.1126/science.92.2385.244-a.

No abstract available.

HYDRATED MORPHINE DERIVATIVES.

Canadian Medical Association journal

[No authors listed]
PMID: 20316207
Can Med Assoc J. 1927 Feb;17(2):251-2.

No abstract available.

How mu-Opioid Receptor Recognizes Fentanyl.

Research square

Vo QN, Mahinthichaichan P, Shen J, Ellis CR.
PMID: 32935088
Res Sq. 2020 Sep 09; doi: 10.21203/rs.3.rs-67888/v1.

The opioid crisis has escalated during the COVID-19 pandemic. More than half of the overdose-related deaths are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In recent years, crystal structures of...

Investigation of CYP2D6 Gene Polymorphisms in Turkish Population.

Psychopharmacology bulletin

Taskin B, Percin FE, Ergun MA.
PMID: 27738374
Psychopharmacol Bull. 2016 Mar 01;46(1):67-72.

Pharmacogenetics is interested in the variable response to drugs depending on the genetic constitution of an individual. Depending on the genetic variation in individuals known as polymorphism; leads to differences in the types of proteins, enzymes or receptors that...

Caregiver drug use in Ontario child welfare investigations: The need for coordinated intervention.

Child abuse & neglect

Joh-Carnella N, Fallon B, Lefebvre R, Lindberg D, Davidson L.
PMID: 34418861
Child Abuse Negl. 2021 Nov;121:105261. doi: 10.1016/j.chiabu.2021.105261. Epub 2021 Aug 19.

BACKGROUND: Caregiver substance abuse is associated with harmful parenting behaviors, increased child welfare involvement, and negative child outcomes, and the opioid epidemic has brought increased attention to the safety and wellbeing of children living with caregivers who abuse substances.OBJECTIVE:...

How .

bioRxiv : the preprint server for biology

Vo QN, Mahinthichaichan P, Shen J, Ellis CR.
PMID: 32839778
bioRxiv. 2020 Nov 25; doi: 10.1101/2020.08.16.253013.

In 2019, drug overdose has claimed over 70,000 lives in the United States. More than half of the deaths are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In recent years,...

Showing 1 to 8 of 8 entries