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Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors?.

Drug development research

Shin Y, Daly JW, Jacobson KA.
PMID: 23087534
Drug Dev Res. 1996 Sep 01;39(1):36-46. doi: 10.1002/(sici)1098-2299(19960901)39:1<36::aid-ddr5>3.0.co;2-l.

A variety of adenosine analogs activate phosphoinositide breakdown in a rat RBL-2H3 mast cell line. It is presumed that an A(3)-adenosine receptor is involved, since the phosphoinositide response is insensitive to xanthines. However, the very potent A(3)- receptor agonist...

Involvement of adenosine receptors in mouse thermoregulation.

Journal of psychopharmacology (Oxford, England)

Zarrindast MR, Heidari MR.
PMID: 22291000
J Psychopharmacol. 1993 Jan;7(4):365-70. doi: 10.1177/026988119300700408.

The effects of the activation of adenosine receptors on core body temperature of mice have been studied in the present investigation. Intraperitoneal (i.p.) injection of non-selective adenosine agonists 5'-N ethyl- carboxamide adenosine (NECA; 0.001, 0.01 and 0.05 mg/kg), R-(N(6)-phenylisopropyl)-adenosine...

The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury.

Korean journal of anesthesiology

Choi DK, Choi SS, Hwang JH.
PMID: 20651997
Korean J Anesthesiol. 2010 Jul;59(1):39-44. doi: 10.4097/kjae.2010.59.1.39. Epub 2010 Jul 21.

BACKGROUND: Nerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model. Therefore, we tested the interaction between intrathecal neostigmine and N(6)-cyclohexyladenosine...

Time-course of the hypomotility effects of the adenosine analogues, cyclohexyladenosine and N-ethylcarboxamidoadenosine, in a holeboard test.

Journal of psychopharmacology (Oxford, England)

Durcan MJ, Morgan PF.
PMID: 22282902
J Psychopharmacol. 1989 Jan;3(3):175-9. doi: 10.1177/026988118900300308.

The time-course of the hypomotility effects of the adenosine analogues 5'-N- ethylcarboxamidoadenosine (NECA) and N(6)-cyclohexyladenosine (CHA) was investigated in a holeboard test. Behaviourally equipotent doses of both compounds given to independent groups of animals showed significant depression of both...

Solubilization of adenosine A(1) binding sites from sheep cortex.

Neurochemistry international

Martini C, Pennacchi E, Poli MG, Lucacchini A.
PMID: 20493013
Neurochem Int. 1985;7(6):1017-20. doi: 10.1016/0197-0186(85)90149-4.

[(3)H]N(6)-cyclohexyladenosine binds with high affinity to sheep brain membranes with a drug specificity indicating an association with A(1) adenosine receptors. The [(3)H]N(6)-cyclohexyladenosine binding site has been solubilized with sodium cholate being the only detergent able to maintain specific binding...

Showing 1 to 5 of 5 entries