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Showing 1 to 9 of 9 entries
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Bioinspired Thermosensitive Hydrogel as a Vitreous Substitute: Synthesis, Properties, and Progress of Animal Studies.

Materials (Basel, Switzerland)

Laradji A, Shui YB, Karakocak BB, Evans L, Hamilton P, Ravi N.
PMID: 32183465
Materials (Basel). 2020 Mar 15;13(6). doi: 10.3390/ma13061337.

In many vitreal diseases, the surgeon removes the natural vitreous and replaces it with silicone oils, gases, or balanced salt solutions to fill the eyeball and hold the retina in position. However, these materials are often associated with complications...

A Precise Method to Evaluate 360 Degree Measures of Optic Cup and Disc Morphology in an African American Cohort and Its Genetic Applications.

Genes

Addis V, Chen M, Zorger R, Salowe R, Daniel E, Lee R, Pistilli M, Gao J, Maguire MG, Chan L, Gudiseva HV, Zenebe-Gete S, Merriam S, Smith EJ, Martin R, Parker Ostroff C, Gee JC, Cui QN, Miller-Ellis E, O'Brien JM, Sankar PS.
PMID: 34946910
Genes (Basel). 2021 Dec 09;12(12). doi: 10.3390/genes12121961.

(1) Background: Vertical cup-to-disc ratio (CDR) is an important measure for evaluating damage to the optic nerve head (ONH) in glaucoma patients. However, this measure often does not fully capture the irregular cupping observed in glaucomatous nerves. We developed...

A Precise Method to Evaluate 360 Degree Measures of Optic Cup and Disc Morphology in an African American Cohort and Its Genetic Applications.

Genes

Addis V, Chen M, Zorger R, Salowe R, Daniel E, Lee R, Pistilli M, Gao J, Maguire MG, Chan L, Gudiseva HV, Zenebe-Gete S, Merriam S, Smith EJ, Martin R, Parker Ostroff C, Gee JC, Cui QN, Miller-Ellis E, O'Brien JM, Sankar PS.
PMID: 34946910
Genes (Basel). 2021 Dec 09;12(12). doi: 10.3390/genes12121961.

(1) Background: Vertical cup-to-disc ratio (CDR) is an important measure for evaluating damage to the optic nerve head (ONH) in glaucoma patients. However, this measure often does not fully capture the irregular cupping observed in glaucomatous nerves. We developed...

A Precise Method to Evaluate 360 Degree Measures of Optic Cup and Disc Morphology in an African American Cohort and Its Genetic Applications.

Genes

Addis V, Chen M, Zorger R, Salowe R, Daniel E, Lee R, Pistilli M, Gao J, Maguire MG, Chan L, Gudiseva HV, Zenebe-Gete S, Merriam S, Smith EJ, Martin R, Parker Ostroff C, Gee JC, Cui QN, Miller-Ellis E, O'Brien JM, Sankar PS.
PMID: 34946910
Genes (Basel). 2021 Dec 09;12(12). doi: 10.3390/genes12121961.

(1) Background: Vertical cup-to-disc ratio (CDR) is an important measure for evaluating damage to the optic nerve head (ONH) in glaucoma patients. However, this measure often does not fully capture the irregular cupping observed in glaucomatous nerves. We developed...

Five-Year Incidence, Management, and Visual Outcomes of Diffuse Lamellar Keratitis after Femtosecond-Assisted LASIK.

Journal of clinical medicine

Moshirfar M, Durnford KM, Lewis AL, Miller CM, West DG, Sperry RA, West WB, Shmunes KM, McCabe SE, Hall MN, Ronquillo YC, Hoopes PC.
PMID: 34300233
J Clin Med. 2021 Jul 11;10(14). doi: 10.3390/jcm10143067.

Femtosecond (FS) lasers initially had a higher incidence of diffuse lamellar keratitis (DLK) compared with microkeratome flap creation. It has been theorized that higher-frequency lower-energy (HFLE) FS lasers would reduce the incidence of DLK. Our study sought to evaluate...

Age at Glaucoma Diagnosis in Germline Myocilin Mutation Patients: Associations with Polymorphisms in Protein Stabilities.

Genes

Tanji T, Cohen E, Shen D, Zhang C, Yu F, Coleman AL, Zheng JJ.
PMID: 34828408
Genes (Basel). 2021 Nov 16;12(11). doi: 10.3390/genes12111802.

Glaucoma is the leading cause of irreversible blindness worldwide, with elevated intraocular pressure (IOP) as the only known modifiable risk factor. Trabecular meshwork (TM)-inducible myocilin (the

Thymosin Beta-4 and Ciprofloxacin Adjunctive Therapy Improves .

Cells

Carion TW, Ebrahim AS, Kracht D, Agrawal A, Strand E, Kaddurah O, McWhirter CR, Sosne G, Berger EA.
PMID: 30241380
Cells. 2018 Sep 20;7(10). doi: 10.3390/cells7100145.

With increasing multidrug resistance and contraindication for corticosteroid use, the goal of this study was to develop thymosin beta-4 (Tβ4) as an adjunctive therapy to antibiotics for the treatment of bacterial keratitis that effectively promotes enhanced wound healing, host...

BACE1 Inhibition Increases Susceptibility to Oxidative Stress by Promoting Mitochondrial Damage.

Antioxidants (Basel, Switzerland)

Francelin C, Mitter SK, Qian Q, Barodia SK, Ip C, Qi X, Gu H, Quigley J, Goldberg MS, Grant MB, Boulton ME.
PMID: 34679674
Antioxidants (Basel). 2021 Sep 28;10(10). doi: 10.3390/antiox10101539.

BACE1 is a key enzyme facilitating the generation of neurotoxic β-amyloid (Aβ) peptide. However, given that BACE1 has multiple substrates we explored the importance of BACE1 in the maintenance of retinal pigment epithelial (RPE) cell homeostasis under oxidative stress....

Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma.

Cancers

Kim ME, Polski A, Xu L, Prabakar RK, Peng CC, Reid MW, Shah R, Kuhn P, Cobrinik D, Hicks J, Berry JL.
PMID: 34283049
Cancers (Basel). 2021 Jul 03;13(13). doi: 10.3390/cancers13133340.

Aqueous humor (AH) liquid biopsy has been established as a surrogate tumor biopsy for retinoblastoma (RB). Previous AH studies have focused on highly recurrent RB somatic copy number alterations (SCNAs) including gain of 1q, 2p, 6p, and loss of...

Showing 1 to 9 of 9 entries