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Refractory neutrophils and monocytes in patients with inflammatory bowel disease after repeated bouts of prolonged exercise.

Cytometry. Part B, Clinical cytometry

Spijkerman R, Hesselink L, Bertinetto C, Bongers CCWG, Hietbrink F, Vrisekoop N, Leenen LPH, Hopman MTE, Jansen JJ, Koenderman L.
PMID: 33683008
Cytometry B Clin Cytom. 2021 Nov;100(6):676-682. doi: 10.1002/cyto.b.21996. Epub 2021 Mar 08.

BACKGROUND: Neutrophils and monocytes are key immune effector cells in inflammatory bowel disease (IBD) that is associated with chronic inflammation in the gut. Patients with stable IBD who perform exercise have significantly fewer flare-ups of the disease, but no...

The influence of extracellular tissue on neutrophil function and its possible linkage to inflammatory diseases.

Immunity, inflammation and disease

Kraus RF, Gruber MA, Kieninger M.
PMID: 34115923
Immun Inflamm Dis. 2021 Dec;9(4):1237-1251. doi: 10.1002/iid3.472. Epub 2021 Jun 11.

BACKGROUND: Migration, production of reactive oxygen species (ROS), release of myeloperoxidase (MPO), and NETosis are functional immunological reactions of elementary importance for polymorphonuclear neutrophils (PMN). Unregulated inflammatory response of PMN within tissues plays a key role in the pathophysiology...

Showing 1 to 2 of 2 entries