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Contributions of S- and R-citalopram to the citalopram-induced modulation of the function of Nav1.5 voltage-gated sodium channels.

European journal of pharmacology

Nakatani Y, Amano T.
PMID: 34280395
Eur J Pharmacol. 2021 Oct 05;908:174316. doi: 10.1016/j.ejphar.2021.174316. Epub 2021 Jul 16.

Citalopram, a selective serotonin reuptake inhibitor (SSRI), has been reported to have adverse effects such as cardiotoxicity, including prolongation of the QTc interval. Although citalopram is well known to be a racemic compound comprised of S-citalopram (escitalopram) and R-citalopram,...

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