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Showing 1 to 12 of 240 entries
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Neopterin levels in patients with cerebrovascular disease.

The Eurasian journal of medicine

Ulvi H, Emre H, Demir R, Aygul R, Varoğlu A, Kara F.
PMID: 25610033
Eurasian J Med. 2008 Aug;40(2):79-82.

OBJECTIVE: The recovery period in ischemic cerebrovascular disease is sometimes long and complicated. It is thought that a systemic inflammatory response plays an important role in this process. Therefore, promising studies have reported that neopterin and other cytokines serve...

A case of post-transplant adult T-cell leukemia/lymphoma presenting myelopathy similar to but distinct from human T-cell leukemia virus type I (HTLV- I)-associated myelopathy.

SpringerPlus

Kawamata T, Ohno N, Sato K, Kobayashi M, Jo N, Yuji K, Tanosaki R, Yamano Y, Tojo A, Uchimaru K.
PMID: 25332881
Springerplus. 2014 Oct 04;3:581. doi: 10.1186/2193-1801-3-581. eCollection 2014.

INTRODUCTION: Adult T-cell leukemia/lymphoma (ATL) responds poorly to conventional chemotherapy, but allogeneic stem cell transplantation (allo-SCT) may improve disease prognosis. Herein, we report a female patient with human T-cell leukemia virus type I (HTLV-I)-associated myelopathy (HAM)-like myelopathy following allo-SCT...

Urinary neopterin levels in patients with thyroid cancer.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

Inancli SS, Caner S, Balkan F, Tam AA, Guler G, Ersoy R, Cakir B.
PMID: 25032119
Indian J Otolaryngol Head Neck Surg. 2014 Sep;66(3):302-8. doi: 10.1007/s12070-014-0710-x. Epub 2014 Feb 18.

Increased urinary neopterin concentrations have been described in many cancers. We aimed to evaluate the urinary neopterin levels in thyroid cancer. Sixty-nine patients with thyroid cancer, 76 patients with benign thyroid pathology and 33 healthy subjects were evaluated. First...

Phase I-II study of gamma interferon and 5-fluorouracil for patients with metastatic renal cell carcinoma.

Cancer biotherapy & radiopharmaceuticals

DeLima M, Amato RJ, Jackson A, Tu SM, Banks M, Finn L, Ellerhorst J.
PMID: 10851489
Cancer Biother Radiopharm. 1997 Dec;12(6):365-70. doi: 10.1089/cbr.1997.12.365.

We have completed a phase I/II trial to evaluate the toxicity and efficacy of the combination of gamma interferon and 5-fluorouracil in metastatic renal cell carcinoma. Gamma interferon was administered at a weekly dose of 100 micrograms. 5-fluorouracil was...

The influence of hypercholesterolemia on some aspects of immune pattern in the elderly.

Archives of gerontology and geriatrics

Allegra A, Corica F, Di Cesare E, Giacobbe MS, Buda G, Ceruso D.
PMID: 15374376
Arch Gerontol Geriatr. 1992 Jul-Aug;15(1):13-9. doi: 10.1016/0167-4943(92)90035-3.

In order to investigate if age related dislipidemia was associated with immunological changes in vivo, humoral, soluble and cellular immune parameters were evaluated both in elderly with and without hypercholesterolemia and in young adults. Significantly increased IgG and IgA...

Randomised controlled trial of weekly chloroquine to re-establish normal erythron iron flux and haemoglobin recovery in postmalarial anaemia.

BMJ open

Cox SE, Nweneka CV, Doherty CP, Fulford AJ, Moore SE, Prentice AM.
PMID: 23833120
BMJ Open. 2013 Jul 04;3(7). doi: 10.1136/bmjopen-2013-002666. Print 2013.

OBJECTIVE: To determine if low-dose weekly chloroquine (CQ) therapy improves recovery from malaria-associated anaemia.DESIGN: Proof of concept randomised clinical trial.SETTING: West Kiang District, Lower River Region, The Gambia.PARTICIPANTS: Children resident in participating communities, aged 12-72 months, with uncomplicated malaria...

An immunosuppressive subtype of neutrophils identified in patients with hepatocellular carcinoma.

Journal of clinical biochemistry and nutrition

Tsuda Y, Fukui H, Asai A, Fukunishi S, Miyaji K, Fujiwara S, Teramura K, Fukuda A, Higuchi K.
PMID: 23170048
J Clin Biochem Nutr. 2012 Nov;51(3):204-12. doi: 10.3164/jcbn.12-32. Epub 2012 Oct 12.

Functional disorders of various immune cells have been reported in hepatocellular carcinoma (HCC) patients. Recently, distinct subsets of neutrophils (polymorphonuclear leukocytes, PMN) have been identified in hosts with enhanced or impaired cell-mediated immunity. In this study, therefore, plasma factors...

Urinary neopterin and phenylalanine loading test as tools for the biochemical diagnosis of segawa disease.

JIMD reports

Leuzzi V, Carducci C, Chiarotti F, D'Agnano D, Giannini MT, Antonozzi I, Carducci C.
PMID: 23430498
JIMD Rep. 2013;7:67-75. doi: 10.1007/8904_2012_144. Epub 2012 Apr 18.

Background. The diagnosis of autosomal dominant GTP-cyclohydrolase deficiency relies on the examination of the GCH1 gene and/or pterins and neurotransmitters in CSF. The aim of the study was to assess the diagnostic value, if any, of pterins in urine...

Association of inflammatory and oxidative stress markers with metabolic syndrome in asian indians in India.

Cardiology research and practice

Rao VS, Nagaraj RK, Hebbagodi S, Kadarinarasimhiah NB, Kakkar VV.
PMID: 21234321
Cardiol Res Pract. 2010 Dec 28;2011:295976. doi: 10.4061/2011/295976.

Metabolic syndrome (MetS) is a primary risk factor for cardiovascular disease and is associated with a proinflammatory state. Here, we assessed the contribution of inflammatory and oxidative stress markers towards prediction of MetS. A total of 2316 individuals were...

The clinical and biochemical parameters in relation to the serum neopterin levels in Indian children and adolescents.

Journal of clinical and diagnostic research : JCDR

Nageswara Rao G S, Gurumurthy P, E S, Cherian KM.
PMID: 23730631
J Clin Diagn Res. 2013 Apr;7(4):618-21. doi: 10.7860/JCDR/2013/5128.2866. Epub 2013 Apr 01.

INTRODUCTION: An adverse pattern of blood lipids and cardiovascular abnormalities starts in obese children during childhood and neopterin serves as a marker for cardiovascular disease. Unfortunately, the data for children and adolescents, particularly, in the Indian population, are scarce....

Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase.

Cell & bioscience

Blaszczyk J, Lu Z, Li Y, Yan H, Ji X.
PMID: 25264482
Cell Biosci. 2014 Sep 02;4(1):52. doi: 10.1186/2045-3701-4-52. eCollection 2014.

BACKGROUND: Dihydroneopterin aldolase (DHNA) catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and also the epimerization of DHNP to 7,8-dihydromonapterin. Previously, we determined the crystal structure of Staphylococcus aureus DHNA (SaDHNA) in complex with the substrate analogue neopterin (NP). We...

Serum chitotriosidase and neopterin levels in patients with ankylosing spondylitis.

Therapeutic advances in musculoskeletal disease

Yavuz F, Kesikburun B, Öztürk Ö, Güzelküçük Ü.
PMID: 30854031
Ther Adv Musculoskelet Dis. 2019 Mar 01;11:1759720X19832321. doi: 10.1177/1759720X19832321. eCollection 2019.

BACKGROUND: The aim of this study was to assess the serum chitotriosidase (ChT) and neopterin levels in patients with ankylosing spondylitis (AS) and to evaluate whether serum ChT and neopterin levels are related to disease activity.METHODS: A total of...

Showing 1 to 12 of 240 entries