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Showing 1 to 3 of 3 entries
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Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity.

Oncogene

Cherif C, Nguyen DT, Paris C, Le TK, Sefiane T, Carbuccia N, Finetti P, Chaffanet M, Kaoutari AE, Vernerey J, Fazli L, Gleave M, Manai M, Barthélémy P, Birnbaum D, Bertucci F, Taïeb D, Rocchi P.
PMID: 34711954
Oncogene. 2022 Jan;41(1):125-137. doi: 10.1038/s41388-021-02039-2. Epub 2021 Oct 28.

Disease progression and therapeutic resistance of prostate cancer (PC) are linked to multiple molecular events that promote survival and plasticity. We previously showed that heat shock protein 27 (HSP27) acted as a driver of castration-resistant phenotype (CRPC) and developed...

Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity.

Oncogene

Cherif C, Nguyen DT, Paris C, Le TK, Sefiane T, Carbuccia N, Finetti P, Chaffanet M, Kaoutari AE, Vernerey J, Fazli L, Gleave M, Manai M, Barthélémy P, Birnbaum D, Bertucci F, Taïeb D, Rocchi P.
PMID: 34711954
Oncogene. 2021 Oct 28; doi: 10.1038/s41388-021-02039-2. Epub 2021 Oct 28.

Disease progression and therapeutic resistance of prostate cancer (PC) are linked to multiple molecular events that promote survival and plasticity. We previously showed that heat shock protein 27 (HSP27) acted as a driver of castration-resistant phenotype (CRPC) and developed...

Oligonucleotidic therapeutics.

Expert opinion on drug discovery

Isaka Y, Imai E, Takahara S, Rakugi H.
PMID: 23506175
Expert Opin Drug Discov. 2008 Sep;3(9):991-6. doi: 10.1517/17460441.3.9.991.

Numerous oligonucleotide-based biopharmaceuticals have been tested to suppress disease progression. These potent therapeutics include plasmids containing transgenes, antisense oligonucleotides, ribozymes, DNAzymes, decoys, aptamers and small interfering RNAs. This perspective discusses the mechanisms and clinical applications of such oligonucleotidic therapeutics....

Showing 1 to 3 of 3 entries