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Showing 1 to 12 of 78 entries
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Basics of Sterile Compounding: Ophthalmic Preparations, Part 1: Ophthalmic Solutions.

International journal of pharmaceutical compounding

Allen LV.
PMID: 28339375
Int J Pharm Compd. 2016 Sep-Oct;20(5):399-404.

Ophthalmic preparations are used to treat allergies, bacterial and viral infections, glaucoma, and numerous other eye conditions. When the eye's natural defensive mechanisms are compromised or overcome, an ophthalmic preparation, in a solution, suspension, or ointment form, may be...

Changes in trend of newly prescribed anti-glaucoma medications in recent nine years in a Japanese local community.

The open ophthalmology journal

Kashiwagi K.
PMID: 20556196
Open Ophthalmol J. 2010 Apr 28;4:7-11. doi: 10.2174/1874364101004010007.

PURPOSE: To investigate changes in the trend of anti-glaucoma ophthalmic solutions in 2000-2008 in a Japanese local community.MATERIALS AND METHODS: The subjects of this study were patients with glaucoma who were registered in the database of the glaucoma clinic...

In vivo comparative study of ocular vasodilation, a relative indicator of hyperemia, in guinea pigs following treatment with bimatoprost ophthalmic solutions 0.01% and 0.03%.

Clinical ophthalmology (Auckland, N.Z.)

Ogundele AB, Earnest D, McLaughlin MA.
PMID: 20689777
Clin Ophthalmol. 2010 Jul 30;4:649-52. doi: 10.2147/opth.s10444.

OBJECTIVE: The objective of this in vivo study was to compare the incidence of vasodilation in guinea pigs following topical administration of bimatoprost ophthalmic solutions 0.01% and 0.03%.METHODS: The study comprised 20 guinea pigs assigned to 2 treatment groups...

Olopatadine ophthalmic solution suppresses substance P release in the conjunctivitis models.

Asia Pacific allergy

Tamura T.
PMID: 22701861
Asia Pac Allergy. 2012 Apr;2(2):115-21. doi: 10.5415/apallergy.2012.2.2.115. Epub 2012 Apr 23.

BACKGROUND: Olopatadine hydrochloride ophthalmic solutions are treated for allergic conjunctival diseases that are a selective histamine H1 receptor antagonist and an inhibitor of the release of mediators including histamine from the human mast cells. Substance P (SP) levels are...

Antiglaucoma drugs: The role of preservative-free formulations.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

Bagnis A, Papadia M, Scotto R, Traverso CE.
PMID: 23960953
Saudi J Ophthalmol. 2011 Oct;25(4):389-94. doi: 10.1016/j.sjopt.2011.08.004. Epub 2011 Aug 28.

Hypersensitive reactions to eyedrops are a common finding in clinical practice and represent a frequent cause of discontinuation of the therapy. Moreover, experimental and clinical studies show that long term use of topical drugs may induce ocular surface changes...

Annual direct cost of dry eye in Japan.

Clinical ophthalmology (Auckland, N.Z.)

Mizuno Y, Yamada M, Shigeyasu C.
PMID: 22654503
Clin Ophthalmol. 2012;6:755-60. doi: 10.2147/OPTH.S30625. Epub 2012 May 16.

BACKGROUND: This study was performed to estimate the annual direct cost incurred by dry eye patients, which includes expenses for treatment and drugs, as well as the cost of punctal plugs.METHODS: The study group consisted of 118 dry eye...

Changes of tear film lipid layer thickness by 3% diquafosol ophthalmic solutions in patients with dry eye syndrome.

International journal of ophthalmology

Kang DH, Lee YW, Hwang KY, Koh KM, Kwon YA, Kim BY, Song SW, Kim KY.
PMID: 31637190
Int J Ophthalmol. 2019 Oct 18;12(10):1555-1560. doi: 10.18240/ijo.2019.10.06. eCollection 2019.

AIM: To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer.METHODS: A total 124 participants (32 males, 92 females; mean age, 28.9y) diagnosed...

Microbial Contamination and Antimicrobial Resistance in Use of Ophthalmic Solutions at the Department of Ophthalmology, Jimma University Specialized Hospital, Southwest Ethiopia.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Tamrat L, Gelaw Y, Beyene G, Gize A.
PMID: 31178944
Can J Infect Dis Med Microbiol. 2019 Apr 15;2019:5372530. doi: 10.1155/2019/5372530. eCollection 2019.

BACKGROUND: Eye drops are most frequently used medications in ophthalmology. The carriage of pathogenic organisms to eyes through the agency of eye drops has presented a serious problem for several decades. The objective of this study was to determine...

Scleral growth stunting via sub-Tenon injection of cross-linking solutions in live rabbits.

The British journal of ophthalmology

Hoang QV, Wen Q, Paik DC, Chun YY, Silverman R, Nagasaki T, Trokel SL, Zyablitskaya M.
PMID: 34670748
Br J Ophthalmol. 2021 Oct 20; doi: 10.1136/bjophthalmol-2021-319427. Epub 2021 Oct 20.

BACKGROUND: Scleral cross-linking is a potential method to inhibit axial elongation of the eye, preventing the progression of pathological myopia. Formaldehyde releasers, which are common preservatives found in cosmetics and ophthalmic solutions, have been shown to be not only...

Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission?.

Microorganisms

Petrillo F, Chianese A, De Bernardo M, Zannella C, Galdiero M, Reibaldi M, Avitabile T, Boccia G, Galdiero M, Rosa N, Franci G.
PMID: 34442628
Microorganisms. 2021 Jul 21;9(8). doi: 10.3390/microorganisms9081550.

In 2020, a global pandemic was declared following the spread of SARS-CoV-2, the pathogen responsible for COVID-19. The risk of infection is high due to the ease of transmission, which can occur orally, through droplets, or via contact with...

Contamination of multi dose eyedrops in the intra and perioperative context.

Scientific reports

Daehn T, Schneider A, Knobloch J, Hellwinkel OJC, Spitzer MS, Kromer R.
PMID: 34645913
Sci Rep. 2021 Oct 13;11(1):20364. doi: 10.1038/s41598-021-99892-8.

In this study, we examined the rate of contamination of multi-dose ophthalmic solutions in the operating theatre and the underlying risk for infection by examining the microbiological load on the tips of the dispenser bottles. A total of 245...

Persistent Corneal Epithelial Defects: A Review Article.

Medical hypothesis, discovery & innovation ophthalmology journal

Vaidyanathan U, Hopping GC, Liu HY, Somani AN, Ronquillo YC, Hoopes PC, Moshirfar M.
PMID: 31598519
Med Hypothesis Discov Innov Ophthalmol. 2019;8(3):163-176.

Persistent corneal epithelial defects (PEDs or PCEDs) result from the failure of rapid re-epithelialization and closure within 10-14 days after a corneal injury, even with standard supportive treatment. Disruptions in the protective epithelial and stromal layers of the cornea...

Showing 1 to 12 of 78 entries