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Converging dopaminergic neurotoxicity mechanisms of antipsychotics, methamphetamine and levodopa.

European review for medical and pharmacological sciences

Zareifopoulos N, Skaltsa M, Dimitriou A, Karveli M, Efthimiou P, Lagadinou M, Tsigkou A, Velissaris D.
PMID: 34286493
Eur Rev Med Pharmacol Sci. 2021 Jul;25(13):4514-4519. doi: 10.26355/eurrev_202107_26243.

OBJECTIVE: Drugs affecting dopaminergic neurotransmission may exert toxic and beneficial effects that persist after discontinuation by modulating gene expression in key brain regions. Drug addiction, cravings and the tardive symptoms associated with chronic exposure to antipsychotics are among the...

Showing 1 to 1 of 1 entries