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Showing 1 to 12 of 35 entries
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Joint Modeling of Longitudinal and Cure-survival Data.

Journal of statistical theory and practice

Kim S, Zeng D, Li Y, Spiegelman D.
PMID: 23926445
J Stat Theory Pract. 2013 Apr 01;7(2):324-344. doi: 10.1080/15598608.2013.772036.

This article presents semiparametric joint models to analyze longitudinal measurements and survival data with a cure fraction. We consider a broad class of transformations for the cure-survival model, which includes the popular proportional hazards structure and the proportional odds...

Ogino et Al. Respond to "the 21st century epidemiologist".

American journal of epidemiology

Ogino S, Beck AH, King EE, Sherman ME, Milner DA, Giovannucci E.
PMID: 22935516
Am J Epidemiol. 2012 Oct 15;176(8):672-4. doi: 10.1093/aje/kws229. Epub 2012 Aug 30.

No abstract available.

Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health science.

American journal of epidemiology

Ogino S, King EE, Beck AH, Sherman ME, Milner DA, Giovannucci E.
PMID: 22935517
Am J Epidemiol. 2012 Oct 15;176(8):659-67. doi: 10.1093/aje/kws226. Epub 2012 Aug 30.

In recent decades, epidemiology, public health, and medical sciences have been increasingly compartmentalized into narrower disciplines. The authors recognize the value of integration of divergent scientific fields in order to create new methods, concepts, paradigms, and knowledge. Herein they...

Continuity of transcriptomes among colorectal cancer subtypes based on meta-analysis.

Genome biology

Ma S, Ogino S, Parsana P, Nishihara R, Qian Z, Shen J, Mima K, Masugi Y, Cao Y, Nowak JA, Shima K, Hoshida Y, Giovannucci EL, Gala MK, Chan AT, Fuchs CS, Parmigiani G, Huttenhower C, Waldron L.
PMID: 30253799
Genome Biol. 2018 Sep 25;19(1):142. doi: 10.1186/s13059-018-1511-4.

BACKGROUND: Previous approaches to defining subtypes of colorectal carcinoma (CRC) and other cancers based on transcriptomes have assumed the existence of discrete subtypes. We analyze gene expression patterns of colorectal tumors from a large number of patients to test...

Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U.
PMID: 32651213
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10.

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAID) is associated with lower risk of colorectal cancer. Genome-wide interaction analysis on single variants (G × E) has identified several SNPs that may interact with NSAIDs to confer colorectal cancer risk,...

Association of .

Clinical cancer research : an official journal of the American Association for Cancer Research

Borowsky J, Haruki K, Lau MC, Dias Costa A, Väyrynen JP, Ugai T, Arima K, da Silva A, Felt KD, Zhao M, Gurjao C, Twombly TS, Fujiyoshi K, Väyrynen SA, Hamada T, Mima K, Bullman S, Harrison TA, Phipps AI, Peters U, Ng K, Meyerhardt JA, Song M, Giovannucci EL, Wu K, Zhang X, Freeman GJ, Huttenhower C, Garrett WS, Chan AT, Leggett BA, Whitehall VLJ, Walker N, Brown I, Bettington M, Nishihara R, Fuchs CS, Lennerz JK, Giannakis M, Nowak JA, Ogino S.
PMID: 33632927
Clin Cancer Res. 2021 May 15;27(10):2816-2826. doi: 10.1158/1078-0432.CCR-20-4009. Epub 2021 Feb 25.

PURPOSE: While evidence indicates that EXPERIMENTAL DESIGN: We measured RESULTS: The amount of CONCLUSIONS: The amount of tissue

The Sulfur Microbial Diet and Risk of Colorectal Cancer by Molecular Subtypes and Intratumoral Microbial Species in Adult Men.

Clinical and translational gastroenterology

Sikavi DR, Nguyen LH, Haruki K, Ugai T, Ma W, Wang DD, Thompson KN, Yan Y, Branck T, Wilkinson JE, Akimoto N, Zhong R, Lau MC, Mima K, Kosumi K, Morikawa T, Rimm EB, Garrett WS, Izard J, Cao Y, Song M, Huttenhower C, Ogino S, Chan AT.
PMID: 34333506
Clin Transl Gastroenterol. 2021 Aug 01;12(8):e00338. doi: 10.14309/ctg.0000000000000338.

INTRODUCTION: We recently described the sulfur microbial diet, a pattern of intake associated with increased gut sulfur-metabolizing bacteria and incidence of distal colorectal cancer (CRC). We assessed whether this risk differed by CRC molecular subtypes or presence of intratumoral...

Discovery and Features of an Alkylating Signature in Colorectal Cancer.

Cancer discovery

Gurjao C, Zhong R, Haruki K, Li YY, Spurr LF, Lee-Six H, Reardon B, Ugai T, Zhang X, Cherniack AD, Song M, Van Allen EM, Meyerhardt JA, Nowak JA, Giovannucci EL, Fuchs CS, Wu K, Ogino S, Giannakis M.
PMID: 34140290
Cancer Discov. 2021 Oct;11(10):2446-2455. doi: 10.1158/2159-8290.CD-20-1656. Epub 2021 Jun 17.

Several risk factors have been established for colorectal cancer, yet their direct mutagenic effects in patients' tumors remain to be elucidated. Here, we leveraged whole-exome sequencing data from 900 colorectal cancer cases that had occurred in three U.S.-wide prospective...

Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location.

Clinical and translational gastroenterology

Mima K, Cao Y, Chan AT, Qian ZR, Nowak JA, Masugi Y, Shi Y, Song M, da Silva A, Gu M, Li W, Hamada T, Kosumi K, Hanyuda A, Liu L, Kostic AD, Giannakis M, Bullman S, Brennan CA, Milner DA, Baba H, Garraway LA, Meyerhardt JA, Garrett WS, Huttenhower C, Meyerson M, Giovannucci EL, Fuchs CS, Nishihara R, Ogino S.
PMID: 27811909
Clin Transl Gastroenterol. 2016 Nov 03;7(11):e200. doi: 10.1038/ctg.2016.53.

OBJECTIVES: Evidence suggests a possible role of Fusobacterium nucleatum in colorectal carcinogenesis, especially in right-sided proximal colorectum. Considering a change in bowel contents and microbiome from proximal to distal colorectal segments, we hypothesized that the proportion of colorectal carcinoma...

Low-Carbohydrate Diet Score and Macronutrient Intake in Relation to Survival After Colorectal Cancer Diagnosis.

JNCI cancer spectrum

Song M, Wu K, Meyerhardt JA, Yilmaz O, Wang M, Ogino S, Fuchs CS, Giovannucci EL, Chan AT.
PMID: 30734025
JNCI Cancer Spectr. 2018 Nov;2(4):pky077. doi: 10.1093/jncics/pky077. Epub 2019 Jan 28.

BACKGROUND: A low-carbohydrate diet may improve cancer survival, but relevant clinical evidence remains limited.METHODS: We followed 1542 stages I to III colorectal cancer (CRC) patients who completed a validated food frequency questionnaire between 6 months and 4 years after...

Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes.

Frontiers in genetics

Pasquale LR, Loomis SJ, Aschard H, Kang JH, Cornelis MC, Qi L, Kraft P, Hu FB.
PMID: 23386860
Front Genet. 2013 Jan 30;4:7. doi: 10.3389/fgene.2013.00007. eCollection 2013.

AIMS/HYPOTHESIS: Genome-wide association studies have identified over 50 new genetic loci for type 2 diabetes (T2D). Several studies conclude that higher dietary heme iron intake increases the risk of T2D. Therefore we assessed whether the relation between genetic loci...

Apolipoprotein C-III as a Potential Modulator of the Association Between HDL-Cholesterol and Incident Coronary Heart Disease.

Journal of the American Heart Association

Jensen MK, Rimm EB, Furtado JD, Sacks FM.
PMID: 23130121
J Am Heart Assoc. 2012 Apr;1(2). doi: 10.1161/JAHA.111.000232. Epub 2012 Apr 24.

BACKGROUND: High-density lipoproteins (HDL) are structurally and metabolically heterogeneous and subclasses with differential effects on coronary heart disease (CHD) might exist. Apolipoprotein (apo) C-III, a small proinflammatory protein that resides on the surface of lipoproteins, enhances the atherogenicity of...

Showing 1 to 12 of 35 entries