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Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy.

Oncotarget

He L, Fan Y, Xiao W, Chen T, Wen J, Dong Y, Wang Y, Li S, Xue R, Zheng L, He JC, Wang N.
PMID: 29340054
Oncotarget. 2017 Nov 30;8(67):111295-111308. doi: 10.18632/oncotarget.22784. eCollection 2017 Dec 19.

Hyperuricemia contributes to kidney tubular injury and kidney fibrosis. However, the underlying mechanism remains unclear. Here we examined the role of RTN1A, a novel endoplasmic reticulum (ER)-associated protein and ER stress in hyperuricemic nephropathy. We first found the expression...

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He L, Fan Y, Xiao W, et al. Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy. Oncotarget. 2017;8(67):111295-111308doi: 10.18632/oncotarget.22784.
He, L., Fan, Y., Xiao, W., Chen, T., Wen, J., Dong, Y., Wang, Y., Li, S., Xue, R., Zheng, L., He, J. C., & Wang, N. (2017). Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy. Oncotarget, 8(67), 111295-111308. https://doi.org/10.18632/oncotarget.22784
He, Li, et al. "Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy." Oncotarget vol. 8,67 (2017): 111295-111308. doi: https://doi.org/10.18632/oncotarget.22784
He L, Fan Y, Xiao W, Chen T, Wen J, Dong Y, Wang Y, Li S, Xue R, Zheng L, He JC, Wang N. Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy. Oncotarget. 2017 Nov 30;8(67):111295-111308. doi: 10.18632/oncotarget.22784. eCollection 2017 Dec 19. PMID: 29340054; PMCID: PMC5762322.
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Absence of HIV-Associated Nephropathy Among Antiretroviral Naive Adults With Persistent Albuminuria in Western Kenya.

Kidney international reports

Koech MK, Owiti MOG, Owino-Ong'or WD, Koskei AK, Karoney MJ, D'Agati VD, Wyatt CM.
PMID: 29142953
Kidney Int Rep. 2016 Nov 30;2(2):159-164. doi: 10.1016/j.ekir.2016.11.007. eCollection 2017 Mar.

INTRODUCTION: HIV-associated nephropathy (HIVAN) has been strongly linked to African ancestry. However, studies have demonstrated wide variability in the prevalence of HIVAN in different sub-Saharan African populations. Accurate assessment of the disease burden is important because antiretroviral therapy (ART)...

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Koech MK, Owiti MOG, Owino-Ong'or WD, et al. Absence of HIV-Associated Nephropathy Among Antiretroviral Naive Adults With Persistent Albuminuria in Western Kenya. Kidney Int Rep. 2016;2(2):159-164doi: 10.1016/j.ekir.2016.11.007.
Koech, M. K., Owiti, M. O. G., Owino-Ong'or, W. D., Koskei, A. K., Karoney, M. J., D'Agati, V. D., & Wyatt, C. M. (2017). Absence of HIV-Associated Nephropathy Among Antiretroviral Naive Adults With Persistent Albuminuria in Western Kenya. Kidney international reports, 2(2), 159-164. https://doi.org/10.1016/j.ekir.2016.11.007
Koech, M K, et al. "Absence of HIV-Associated Nephropathy Among Antiretroviral Naive Adults With Persistent Albuminuria in Western Kenya." Kidney international reports vol. 2,2 (2017): 159-164. doi: https://doi.org/10.1016/j.ekir.2016.11.007
Koech MK, Owiti MOG, Owino-Ong'or WD, Koskei AK, Karoney MJ, D'Agati VD, Wyatt CM. Absence of HIV-Associated Nephropathy Among Antiretroviral Naive Adults With Persistent Albuminuria in Western Kenya. Kidney Int Rep. 2016 Nov 30;2(2):159-164. doi: 10.1016/j.ekir.2016.11.007. eCollection 2017 Mar. PMID: 29142953; PMCID: PMC5678678.
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Proximal tubular dysfunction and kidney injury associated with tenofovir in HIV patients: a case series.

Clinical kidney journal

Waheed S, Attia D, Estrella MM, Zafar Y, Atta MG, Lucas GM, Fine DM.
PMID: 26251709
Clin Kidney J. 2015 Aug;8(4):420-5. doi: 10.1093/ckj/sfv041. Epub 2015 Jun 03.

BACKGROUND: Tenofovir disoproxil fumarate (TDF) may cause acute kidney injury and proximal tubular dysfunction. However, no detailed studies document urinary phosphate wasting as a marker of TDF-induced tubulopathy.METHODS: Records of HIV-infected patients with presumed TDF toxicity were reviewed. We...

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Waheed S, Attia D, Estrella MM, et al. Proximal tubular dysfunction and kidney injury associated with tenofovir in HIV patients: a case series. Clin Kidney J. 2015;8(4):420-5doi: 10.1093/ckj/sfv041.
Waheed, S., Attia, D., Estrella, M. M., Zafar, Y., Atta, M. G., Lucas, G. M., & Fine, D. M. (2015). Proximal tubular dysfunction and kidney injury associated with tenofovir in HIV patients: a case series. Clinical kidney journal, 8(4), 420-5. https://doi.org/10.1093/ckj/sfv041
Waheed, Sana, et al. "Proximal tubular dysfunction and kidney injury associated with tenofovir in HIV patients: a case series." Clinical kidney journal vol. 8,4 (2015): 420-5. doi: https://doi.org/10.1093/ckj/sfv041
Waheed S, Attia D, Estrella MM, Zafar Y, Atta MG, Lucas GM, Fine DM. Proximal tubular dysfunction and kidney injury associated with tenofovir in HIV patients: a case series. Clin Kidney J. 2015 Aug;8(4):420-5. doi: 10.1093/ckj/sfv041. Epub 2015 Jun 03. PMID: 26251709; PMCID: PMC4515896.
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HIV-associated nephropathy: links, risks and management.

HIV/AIDS (Auckland, N.Z.)

Palau L, Menez S, Rodriguez-Sanchez J, Novick T, Delsante M, McMahon BA, Atta MG.
PMID: 29872351
HIV AIDS (Auckl). 2018 May 25;10:73-81. doi: 10.2147/HIV.S141978. eCollection 2018.

Despite the decreased incidence of human immunodeficiency virus (HIV)-associated nephropathy due to the widespread use of combined active antiretroviral therapy, it remains one of the leading causes of end-stage renal disease (ESRD) in HIV-1 seropositive patients. Patients usually present...

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Palau L, Menez S, Rodriguez-Sanchez J, et al. HIV-associated nephropathy: links, risks and management. HIV AIDS (Auckl). 2018;10:73-81doi: 10.2147/HIV.S141978.
Palau, L., Menez, S., Rodriguez-Sanchez, J., Novick, T., Delsante, M., McMahon, B. A., & Atta, M. G. (2018). HIV-associated nephropathy: links, risks and management. HIV/AIDS (Auckland, N.Z.), 1073-81. https://doi.org/10.2147/HIV.S141978
Palau, Laura, et al. "HIV-associated nephropathy: links, risks and management." HIV/AIDS (Auckland, N.Z.) vol. 10 (2018): 73-81. doi: https://doi.org/10.2147/HIV.S141978
Palau L, Menez S, Rodriguez-Sanchez J, Novick T, Delsante M, McMahon BA, Atta MG. HIV-associated nephropathy: links, risks and management. HIV AIDS (Auckl). 2018 May 25;10:73-81. doi: 10.2147/HIV.S141978. eCollection 2018. PMID: 29872351; PMCID: PMC5975615.
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SIRT1 Is a Potential Drug Target for Treatment of Diabetic Kidney Disease.

Frontiers in endocrinology

Zhong Y, Lee K, He JC.
PMID: 30386303
Front Endocrinol (Lausanne). 2018 Oct 17;9:624. doi: 10.3389/fendo.2018.00624. eCollection 2018.

Multiple studies have demonstrated a critical role of Sirtuin-1 (SIRT1) deacetylase in protecting kidney cells from cellular stresses. A protective role of SIRT1 has been reported in both podocytes and renal tubular cells in multiple kidney disease settings, including...

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Zhong Y, Lee K, He JC. SIRT1 Is a Potential Drug Target for Treatment of Diabetic Kidney Disease. Front Endocrinol (Lausanne). 2018;9:624doi: 10.3389/fendo.2018.00624.
Zhong, Y., Lee, K., & He, J. C. (2018). SIRT1 Is a Potential Drug Target for Treatment of Diabetic Kidney Disease. Frontiers in endocrinology, 9624. https://doi.org/10.3389/fendo.2018.00624
Zhong, Yifei, et al. "SIRT1 Is a Potential Drug Target for Treatment of Diabetic Kidney Disease." Frontiers in endocrinology vol. 9 (2018): 624. doi: https://doi.org/10.3389/fendo.2018.00624
Zhong Y, Lee K, He JC. SIRT1 Is a Potential Drug Target for Treatment of Diabetic Kidney Disease. Front Endocrinol (Lausanne). 2018 Oct 17;9:624. doi: 10.3389/fendo.2018.00624. eCollection 2018. PMID: 30386303; PMCID: PMC6199382.
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Showing 1 to 5 of 5 entries