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Computed tomography correlates with cardiopulmonary hemodynamics in pulmonary hypertension in adults with sickle cell disease.

Pulmonary circulation

Linguraru MG, Pura JA, Gladwin MT, Koroulakis AI, Minniti C, Machado RF, Kato GJ, Wood BJ.
PMID: 25006451
Pulm Circ. 2014 Jun;4(2):319-29. doi: 10.1086/675997.

Our objective was to determine whether computed tomography angiography (CTA) measurements of pulmonary artery size can noninvasively assess hemodynamics and diagnose pulmonary hypertension (PH) secondary to sickle cell disease (SCD). Twenty SCD patients with confirmed PH were compared with...

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Linguraru MG, Pura JA, Gladwin MT, et al. Computed tomography correlates with cardiopulmonary hemodynamics in pulmonary hypertension in adults with sickle cell disease. Pulm Circ. 2014;4(2):319-29doi: 10.1086/675997.
Linguraru, M. G., Pura, J. A., Gladwin, M. T., Koroulakis, A. I., Minniti, C., Machado, R. F., Kato, G. J., & Wood, B. J. (2014). Computed tomography correlates with cardiopulmonary hemodynamics in pulmonary hypertension in adults with sickle cell disease. Pulmonary circulation, 4(2), 319-29. https://doi.org/10.1086/675997
Linguraru, Marius George, et al. "Computed tomography correlates with cardiopulmonary hemodynamics in pulmonary hypertension in adults with sickle cell disease." Pulmonary circulation vol. 4,2 (2014): 319-29. doi: https://doi.org/10.1086/675997
Linguraru MG, Pura JA, Gladwin MT, Koroulakis AI, Minniti C, Machado RF, Kato GJ, Wood BJ. Computed tomography correlates with cardiopulmonary hemodynamics in pulmonary hypertension in adults with sickle cell disease. Pulm Circ. 2014 Jun;4(2):319-29. doi: 10.1086/675997. PMID: 25006451; PMCID: PMC4070777.
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HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension.

American journal of respiratory and critical care medicine

Kudryashova TV, Goncharov DA, Pena A, Kelly N, Vanderpool R, Baust J, Kobir A, Shufesky W, Mora AL, Morelli AE, Zhao J, Ihida-Stansbury K, Chang B, DeLisser H, Tuder RM, Kawut SM, Silljé HH, Shapiro S, Zhao Y, Goncharova EA.
PMID: 27119551
Am J Respir Crit Care Med. 2016 Oct 01;194(7):866-877. doi: 10.1164/rccm.201510-2003OC.

RATIONALE: Enhanced proliferation and impaired apoptosis of pulmonary arterial vascular smooth muscle cells (PAVSMCs) are key pathophysiologic components of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH).OBJECTIVES: To determine the role and therapeutic relevance of HIPPO signaling in PAVSMC...

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Kudryashova TV, Goncharov DA, Pena A, et al. HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension. Am J Respir Crit Care Med. 2016;194(7):866-877doi: 10.1164/rccm.201510-2003OC.
Kudryashova, T. V., Goncharov, D. A., Pena, A., Kelly, N., Vanderpool, R., Baust, J., Kobir, A., Shufesky, W., Mora, A. L., Morelli, A. E., Zhao, J., Ihida-Stansbury, K., Chang, B., DeLisser, H., Tuder, R. M., Kawut, S. M., Silljé, H. H., Shapiro, S., Zhao, Y., & Goncharova, E. A. (2016). HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension. American journal of respiratory and critical care medicine, 194(7), 866-877. https://doi.org/10.1164/rccm.201510-2003OC
Kudryashova, Tatiana V, et al. "HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension." American journal of respiratory and critical care medicine vol. 194,7 (2016): 866-877. doi: https://doi.org/10.1164/rccm.201510-2003OC
Kudryashova TV, Goncharov DA, Pena A, Kelly N, Vanderpool R, Baust J, Kobir A, Shufesky W, Mora AL, Morelli AE, Zhao J, Ihida-Stansbury K, Chang B, DeLisser H, Tuder RM, Kawut SM, Silljé HH, Shapiro S, Zhao Y, Goncharova EA. HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension. Am J Respir Crit Care Med. 2016 Oct 01;194(7):866-877. doi: 10.1164/rccm.201510-2003OC. PMID: 27119551; PMCID: PMC5074651.
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Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung.

Cell reports. Medicine

Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA.
PMID: 34873589
Cell Rep Med. 2021 Dec 02;100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 02.

Despite extensive analyses, there remains an urgent need to delineate immune cell states that contribute to mortality in critically ill Coronavirus disease 2019 (COVID-19) patients. Here, we present high-dimensional profiling of blood and respiratory samples in severe COVID-19 patients...

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Cillo AR, Somasundaram A, Shan F, et al. Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung. Cell Rep Med. 2021;100476doi: 10.1016/j.xcrm.2021.100476.
Cillo, A. R., Somasundaram, A., Shan, F., Cardello, C., Workman, C. J., Kitsios, G. D., Ruffin, A., Kunning, S., Lampenfeld, C., Onkar, S., Grebinoski, S., Deshmukh, G., Methe, B., Liu, C., Nambulli, S., Andrews, L., Duprex, W. P., Joglekar, A. V., Benos, P. V., Ray, P., Ray, A., McVerry, B. J., Zhang, Y., Lee, J. S., Das, J., Singh, H., Morris, A., Bruno, T. C., & Vignali, D. A. A. (2021). Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung. Cell reports. Medicine, 100476. https://doi.org/10.1016/j.xcrm.2021.100476
Cillo, Anthony R, et al. "Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung." Cell reports. Medicine vol. (2021): 100476. doi: https://doi.org/10.1016/j.xcrm.2021.100476
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung. Cell Rep Med. 2021 Dec 02;100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 02. PMID: 34873589; PMCID: PMC8636386.
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People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.

Cell reports. Medicine

Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA.
PMID: 34873589
Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 02.

Despite extensive analyses, there remains an urgent need to delineate immune cell states that contribute to mortality in people critically ill with COVID-19. Here, we present high-dimensional profiling of blood and respiratory samples from people with severe COVID-19 to...

Cite
Cillo AR, Somasundaram A, Shan F, et al. People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden. Cell Rep Med. 2021;2(12):100476doi: 10.1016/j.xcrm.2021.100476.
Cillo, A. R., Somasundaram, A., Shan, F., Cardello, C., Workman, C. J., Kitsios, G. D., Ruffin, A. T., Kunning, S., Lampenfeld, C., Onkar, S., Grebinoski, S., Deshmukh, G., Methe, B., Liu, C., Nambulli, S., Andrews, L. P., Duprex, W. P., Joglekar, A. V., Benos, P. V., Ray, P., Ray, A., McVerry, B. J., Zhang, Y., Lee, J. S., Das, J., Singh, H., Morris, A., Bruno, T. C., & Vignali, D. A. A. (2021). People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden. Cell reports. Medicine, 2(12), 100476. https://doi.org/10.1016/j.xcrm.2021.100476
Cillo, Anthony R, et al. "People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden." Cell reports. Medicine vol. 2,12 (2021): 100476. doi: https://doi.org/10.1016/j.xcrm.2021.100476
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden. Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 02. PMID: 34873589; PMCID: PMC8636386.
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Pulmonary Hypertension in the Context of Heart Failure With Preserved Ejection Fraction.

Chest

Inampudi C, Silverman D, Simon MA, Leary PJ, Sharma K, Houston BA, Vachiéry JL, Haddad F, Tedford RJ.
PMID: 34391755
Chest. 2021 Dec;160(6):2232-2246. doi: 10.1016/j.chest.2021.08.039. Epub 2021 Aug 12.

Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure and frequently is associated with pulmonary hypertension (PH). HFpEF associated with PH may be difficult to distinguish from precapillary forms of PH, although this...

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Inampudi C, Silverman D, Simon MA, et al. Pulmonary Hypertension in the Context of Heart Failure With Preserved Ejection Fraction. Chest. 2021;160(6):2232-2246doi: 10.1016/j.chest.2021.08.039.
Inampudi, C., Silverman, D., Simon, M. A., Leary, P. J., Sharma, K., Houston, B. A., Vachiéry, J. L., Haddad, F., & Tedford, R. J. (2021). Pulmonary Hypertension in the Context of Heart Failure With Preserved Ejection Fraction. Chest, 160(6), 2232-2246. https://doi.org/10.1016/j.chest.2021.08.039
Inampudi, Chakradhari, et al. "Pulmonary Hypertension in the Context of Heart Failure With Preserved Ejection Fraction." Chest vol. 160,6 (2021): 2232-2246. doi: https://doi.org/10.1016/j.chest.2021.08.039
Inampudi C, Silverman D, Simon MA, Leary PJ, Sharma K, Houston BA, Vachiéry JL, Haddad F, Tedford RJ. Pulmonary Hypertension in the Context of Heart Failure With Preserved Ejection Fraction. Chest. 2021 Dec;160(6):2232-2246. doi: 10.1016/j.chest.2021.08.039. Epub 2021 Aug 12. PMID: 34391755.
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Exercise-induced changes of vital signs in adults with sickle cell disease.

American journal of hematology

Johnson S, Gordeuk VR, Machado R, Gibbs JSR, Hildesheim M, Little JA, Kato GJ, Gladwin MT, Nouraie M.
PMID: 34626431
Am J Hematol. 2021 Dec 01;96(12):1630-1638. doi: 10.1002/ajh.26369. Epub 2021 Oct 20.

The six-minute walk test (6MWT) has been used in patients with sickle cell disease (SCD), in conjunction with tricuspid regurgitant velocity (TRV) and plasma N-terminal pro-brain natriuretic peptide (NT-pro BNP), to assess risk of having pulmonary hypertension. Exercise-induced vital...

Cite
Johnson S, Gordeuk VR, Machado R, et al. Exercise-induced changes of vital signs in adults with sickle cell disease. Am J Hematol. 2021;96(12):1630-1638doi: 10.1002/ajh.26369.
Johnson, S., Gordeuk, V. R., Machado, R., Gibbs, J. S. R., Hildesheim, M., Little, J. A., Kato, G. J., Gladwin, M. T., & Nouraie, M. (2021). Exercise-induced changes of vital signs in adults with sickle cell disease. American journal of hematology, 96(12), 1630-1638. https://doi.org/10.1002/ajh.26369
Johnson, Solomon, et al. "Exercise-induced changes of vital signs in adults with sickle cell disease." American journal of hematology vol. 96,12 (2021): 1630-1638. doi: https://doi.org/10.1002/ajh.26369
Johnson S, Gordeuk VR, Machado R, Gibbs JSR, Hildesheim M, Little JA, Kato GJ, Gladwin MT, Nouraie M. Exercise-induced changes of vital signs in adults with sickle cell disease. Am J Hematol. 2021 Dec 01;96(12):1630-1638. doi: 10.1002/ajh.26369. Epub 2021 Oct 20. PMID: 34626431; PMCID: PMC8616821.
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Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.

Circulation

Satoh T, Wang L, Espinosa-Diez C, Wang B, Hahn SA, Noda K, Rochon ER, Dent MR, Levine AR, Baust JJ, Wyman S, Wu YL, Triantafyllou GA, Tang Y, Reynolds M, Shiva S, Hilaire CS, Gomez D, Goncharov DA, Goncharova EA, Chan SY, Straub AC, Lai YC, McTiernan CF, Gladwin MT.
PMID: 34157861
Circulation. 2021 Aug 24;144(8):615-637. doi: 10.1161/CIRCULATIONAHA.121.053889. Epub 2021 Jun 23.

BACKGROUND: Many patients with heart failure with preserved ejection fraction have metabolic syndrome and develop exercise-induced pulmonary hypertension (EIPH). Increases in pulmonary vascular resistance in patients with heart failure with preserved ejection fraction portend a poor prognosis; this phenotype...

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Satoh T, Wang L, Espinosa-Diez C, et al. Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction. Circulation. 2021;144(8):615-637doi: 10.1161/CIRCULATIONAHA.121.053889.
Satoh, T., Wang, L., Espinosa-Diez, C., Wang, B., Hahn, S. A., Noda, K., Rochon, E. R., Dent, M. R., Levine, A. R., Baust, J. J., Wyman, S., Wu, Y. L., Triantafyllou, G. A., Tang, Y., Reynolds, M., Shiva, S., Hilaire, C. S., Gomez, D., Goncharov, D. A., Goncharova, E. A., Chan, S. Y., Straub, A. C., Lai, Y. C., McTiernan, C. F., & Gladwin, M. T. (2021). Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction. Circulation, 144(8), 615-637. https://doi.org/10.1161/CIRCULATIONAHA.121.053889
Satoh, Taijyu, et al. "Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction." Circulation vol. 144,8 (2021): 615-637. doi: https://doi.org/10.1161/CIRCULATIONAHA.121.053889
Satoh T, Wang L, Espinosa-Diez C, Wang B, Hahn SA, Noda K, Rochon ER, Dent MR, Levine AR, Baust JJ, Wyman S, Wu YL, Triantafyllou GA, Tang Y, Reynolds M, Shiva S, Hilaire CS, Gomez D, Goncharov DA, Goncharova EA, Chan SY, Straub AC, Lai YC, McTiernan CF, Gladwin MT. Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction. Circulation. 2021 Aug 24;144(8):615-637. doi: 10.1161/CIRCULATIONAHA.121.053889. Epub 2021 Jun 23. PMID: 34157861; PMCID: PMC8384699.
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Inflammatory signaling and metabolic regulation by nitro-fatty acids.

Nitric oxide : biology and chemistry

Rom O, Khoo NKH, Chen YE, Villacorta L.
PMID: 29578057
Nitric Oxide. 2018 Mar 22; doi: 10.1016/j.niox.2018.03.017. Epub 2018 Mar 22.

The addition of nitrogen dioxide (NO

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Rom O, Khoo NKH, Chen YE, et al. Inflammatory signaling and metabolic regulation by nitro-fatty acids. Nitric Oxide. 2018;doi: 10.1016/j.niox.2018.03.017.
Rom, O., Khoo, N. K. H., Chen, Y. E., & Villacorta, L. (2018). Inflammatory signaling and metabolic regulation by nitro-fatty acids. Nitric oxide : biology and chemistry, . https://doi.org/10.1016/j.niox.2018.03.017
Rom, Oren, et al. "Inflammatory signaling and metabolic regulation by nitro-fatty acids." Nitric oxide : biology and chemistry vol. (2018). doi: https://doi.org/10.1016/j.niox.2018.03.017
Rom O, Khoo NKH, Chen YE, Villacorta L. Inflammatory signaling and metabolic regulation by nitro-fatty acids. Nitric Oxide. 2018 Mar 22; doi: 10.1016/j.niox.2018.03.017. Epub 2018 Mar 22. PMID: 29578057; PMCID: PMC6151155.
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A Novel Acquisition Technique to Utilize Swan-Ganz Catheter data as a Surrogate for High-fidelity Micromanometry within the Right Ventricle and Pulmonary Circuit.

Cardiovascular engineering and technology

Bachman TN, Bursic JJ, Simon MA, Champion HC.
PMID: 25484997
Cardiovasc Eng Technol. 2013 Jun 01;4(2):183-191. doi: 10.1007/s13239-013-0124-z.

We explored the possibility of using conventional right-heart catheterization data, gathered both prospectively and retrospectively, as a surrogate for high-fidelity micro-manometery when analyzing systolic and diastolic RV function and calculating various ventricular and pulmonary hemodynamic parameters in the time...

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Bachman TN, Bursic JJ, Simon MA, et al. A Novel Acquisition Technique to Utilize Swan-Ganz Catheter data as a Surrogate for High-fidelity Micromanometry within the Right Ventricle and Pulmonary Circuit. Cardiovasc Eng Technol. 2013;4(2):183-191doi: 10.1007/s13239-013-0124-z.
Bachman, T. N., Bursic, J. J., Simon, M. A., & Champion, H. C. (2013). A Novel Acquisition Technique to Utilize Swan-Ganz Catheter data as a Surrogate for High-fidelity Micromanometry within the Right Ventricle and Pulmonary Circuit. Cardiovascular engineering and technology, 4(2), 183-191. https://doi.org/10.1007/s13239-013-0124-z
Bachman, T N, et al. "A Novel Acquisition Technique to Utilize Swan-Ganz Catheter data as a Surrogate for High-fidelity Micromanometry within the Right Ventricle and Pulmonary Circuit." Cardiovascular engineering and technology vol. 4,2 (2013): 183-191. doi: https://doi.org/10.1007/s13239-013-0124-z
Bachman TN, Bursic JJ, Simon MA, Champion HC. A Novel Acquisition Technique to Utilize Swan-Ganz Catheter data as a Surrogate for High-fidelity Micromanometry within the Right Ventricle and Pulmonary Circuit. Cardiovasc Eng Technol. 2013 Jun 01;4(2):183-191. doi: 10.1007/s13239-013-0124-z. PMID: 25484997; PMCID: PMC4254723.
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People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.

Cell reports. Medicine

Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA.
PMID: 34873589
Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 02.

Despite extensive analyses, there remains an urgent need to delineate immune cell states that contribute to mortality in people critically ill with COVID-19. Here, we present high-dimensional profiling of blood and respiratory samples from people with severe COVID-19 to...

Cite
Cillo AR, Somasundaram A, Shan F, et al. People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden. Cell Rep Med. 2021;2(12):100476doi: 10.1016/j.xcrm.2021.100476.
Cillo, A. R., Somasundaram, A., Shan, F., Cardello, C., Workman, C. J., Kitsios, G. D., Ruffin, A. T., Kunning, S., Lampenfeld, C., Onkar, S., Grebinoski, S., Deshmukh, G., Methe, B., Liu, C., Nambulli, S., Andrews, L. P., Duprex, W. P., Joglekar, A. V., Benos, P. V., Ray, P., Ray, A., McVerry, B. J., Zhang, Y., Lee, J. S., Das, J., Singh, H., Morris, A., Bruno, T. C., & Vignali, D. A. A. (2021). People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden. Cell reports. Medicine, 2(12), 100476. https://doi.org/10.1016/j.xcrm.2021.100476
Cillo, Anthony R, et al. "People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden." Cell reports. Medicine vol. 2,12 (2021): 100476. doi: https://doi.org/10.1016/j.xcrm.2021.100476
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden. Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 02. PMID: 34873589; PMCID: PMC8636386.
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Exercise-induced changes of vital signs in adults with sickle cell disease.

American journal of hematology

Johnson S, Gordeuk VR, Machado R, Gibbs JSR, Hildesheim M, Little JA, Kato GJ, Gladwin MT, Nouraie M.
PMID: 34626431
Am J Hematol. 2021 Dec 01;96(12):1630-1638. doi: 10.1002/ajh.26369. Epub 2021 Oct 20.

The six-minute walk test (6MWT) has been used in patients with sickle cell disease (SCD), in conjunction with tricuspid regurgitant velocity (TRV) and plasma N-terminal pro-brain natriuretic peptide (NT-pro BNP), to assess risk of having pulmonary hypertension. Exercise-induced vital...

Cite
Johnson S, Gordeuk VR, Machado R, et al. Exercise-induced changes of vital signs in adults with sickle cell disease. Am J Hematol. 2021;96(12):1630-1638doi: 10.1002/ajh.26369.
Johnson, S., Gordeuk, V. R., Machado, R., Gibbs, J. S. R., Hildesheim, M., Little, J. A., Kato, G. J., Gladwin, M. T., & Nouraie, M. (2021). Exercise-induced changes of vital signs in adults with sickle cell disease. American journal of hematology, 96(12), 1630-1638. https://doi.org/10.1002/ajh.26369
Johnson, Solomon, et al. "Exercise-induced changes of vital signs in adults with sickle cell disease." American journal of hematology vol. 96,12 (2021): 1630-1638. doi: https://doi.org/10.1002/ajh.26369
Johnson S, Gordeuk VR, Machado R, Gibbs JSR, Hildesheim M, Little JA, Kato GJ, Gladwin MT, Nouraie M. Exercise-induced changes of vital signs in adults with sickle cell disease. Am J Hematol. 2021 Dec 01;96(12):1630-1638. doi: 10.1002/ajh.26369. Epub 2021 Oct 20. PMID: 34626431; PMCID: PMC8616821.
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Bifurcated monocyte states are predictive of mortality in severe COVID-19.

bioRxiv : the preprint server for biology

Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA.
PMID: 33594364
bioRxiv. 2021 Feb 10; doi: 10.1101/2021.02.10.430499.

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection presents with varied clinical manifestations

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Cillo AR, Somasundaram A, Shan F, et al. Bifurcated monocyte states are predictive of mortality in severe COVID-19. bioRxiv. 2021;doi: 10.1101/2021.02.10.430499.
Cillo, A. R., Somasundaram, A., Shan, F., Cardello, C., Workman, C. J., Kitsios, G. D., Ruffin, A., Kunning, S., Lampenfeld, C., Onkar, S., Grebinoski, S., Deshmukh, G., Methe, B., Liu, C., Nambulli, S., Andrews, L., Duprex, W. P., Joglekar, A. V., Benos, P. V., Ray, P., Ray, A., McVerry, B. J., Zhang, Y., Lee, J. S., Das, J., Singh, H., Morris, A., Bruno, T. C., & Vignali, D. A. A. (2021). Bifurcated monocyte states are predictive of mortality in severe COVID-19. bioRxiv : the preprint server for biology, . https://doi.org/10.1101/2021.02.10.430499
Cillo, Anthony R, et al. "Bifurcated monocyte states are predictive of mortality in severe COVID-19." bioRxiv : the preprint server for biology vol. (2021). doi: https://doi.org/10.1101/2021.02.10.430499
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Bifurcated monocyte states are predictive of mortality in severe COVID-19. bioRxiv. 2021 Feb 10; doi: 10.1101/2021.02.10.430499. PMID: 33594364; PMCID: PMC7885916.
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