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Showing 1 to 9 of 9 entries
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Identification of a novel functional miR-143-5p recognition element in the Cystic Fibrosis Transmembrane Conductance Regulator 3'UTR.

AIMS genetics

De Santi C, Gadi S, Swiatecka-Urban A, Greene CM.
PMID: 31435512
AIMS Genet. 2018 Feb 23;5(1):53-62. doi: 10.3934/genet.2018.1.53. eCollection 2018.

MicroRNAs (miRNAs) are small non-coding RNAs involved in regulation of gene expression. They bind in a sequence-specific manner to miRNA recognition elements (MREs) located in the 3' untranslated region (UTR) of target mRNAs and prevent mRNA translation. MiRNA expression...

The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels.

Cardiology research and practice

Coffey CS, Asselbergs FW, Hebert PR, Hillege HL, Li Q, Moore JH, van Gilst WH.
PMID: 21559217
Cardiol Res Pract. 2011 Apr 04;2011:541467. doi: 10.4061/2011/541467.

Background. We used a random sample (n = 2, 495) from the population-based Prevention of Renal and Vascular End-stage Disease (PREVEND) study population to examine the association of the metabolic syndrome (Met S) with plasminogen activator inhibitor type 1...

Exploratory Visual Analysis of statistical results from microarray experiments comparing high and low grade glioma.

Cancer informatics

Reif DM, Israel MA, Moore JH.
PMID: 19390666
Cancer Inform. 2007;5:19-24. Epub 2007 Apr 01.

The biological interpretation of gene expression microarray results is a daunting challenge. For complex diseases such as cancer, wherein the body of published research is extensive, the incorporation of expert knowledge provides a useful analytical framework. We have previously...

Endocytic Trafficking at the Mature Podocyte Slit Diaphragm.

Frontiers in pediatrics

Swiatecka-Urban A.
PMID: 28286744
Front Pediatr. 2017 Feb 24;5:32. doi: 10.3389/fped.2017.00032. eCollection 2017.

Endocytic trafficking couples cell signaling with the cytoskeletal dynamics by organizing a crosstalk between protein networks in different subcellular compartments. Proteins residing in the plasma membrane are internalized and transported as cargo in endocytic vesicles (i.e., endocytosis). Subsequently, cargo...

Indoor and Outdoor Air Pollution and Lung Cancer in New Hampshire and Vermont.

Toxicological and environmental chemistry

Sloan CD, Andrew AS, Gruber JF, Mwenda KM, Moore JH, Onega T, Karagas MR, Shi X, Duell EJ.
PMID: 24273369
Toxicol Environ Chem. 2012 Jan 01;94(3). doi: 10.1080/02772248.2012.659930.

Indoor and outdoor air pollution is known to contribute to increased lung cancer incidence. This study is the first to address the contribution of home heating fuel and geographical course particulate matter (PM

The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies.

Current pharmacogenomics and personalized medicine

Wilke RA, Mareedu RK, Moore JH.
PMID: 19421424
Curr Pharmacogenomics Person Med. 2008;6(3):150-159. doi: 10.2174/1875692110806030150.

The candidate gene approach to pharmacogenetics is hypothesis driven, and anchored in biological plausibility. Whole genome scanning is hypothesis generating, and it may lead to new biology. While both approaches are important, the scientific community is rapidly reallocating resources...

Environmentally Endemic Pseudomonas aeruginosa Strains with Mutations in lasR Are Associated with Increased Disease Severity in Corneal Ulcers.

mSphere

Hammond JH, Hebert WP, Naimie A, Ray K, Van Gelder RD, DiGiandomenico A, Lalitha P, Srinivasan M, Acharya NR, Lietman T, Hogan DA, Zegans ME.
PMID: 27631025
mSphere. 2016 Sep 07;1(5). doi: 10.1128/mSphere.00140-16. eCollection 2016.

The Steroids for Corneal Ulcers Trial (SCUT) was a multicenter, international study of bacterial keratitis in which 101 Pseudomonas aeruginosa infections were treated. Twenty-two of 101 P. aeruginosa isolates collected had a colony morphology characteristic of a loss-of-function mutation...

Evaluation of biodiesel's impact on real-world occupational and environmental particulate matter exposures at a municipal facility in Keene, NH.

Air quality, atmosphere, & health

Traviss N, Thelen BA, Ingalls JK, Treadwell MD.
PMID: 29910840
Air Qual Atmos Health. 2012 Mar;5(1):101-114. doi: 10.1007/s11869-011-0141-8. Epub 2011 Mar 23.

Many organizations are interested in biodiesel as a renewable, domestic energy source for use in transportation and heavy-duty equipment. Although numerous biodiesel

Breathing easier? The known impacts of biodiesel on air quality.

Biofuels

Traviss N.
PMID: 23585814
Biofuels. 2012 May;3(3):285-291. doi: 10.4155/bfs.12.22.

Substantial scientific evidence exists on the negative health effects of exposure to petroleum diesel exhaust. Many view biodiesel as a 'green', more environmentally friendly alternative fuel, especially with respect to measured reductions of particulate matter in tailpipe emissions. Tailpipe...

Showing 1 to 9 of 9 entries