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Showing 1 to 12 of 97 entries
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Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity.

Vaccines

Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K.
PMID: 26344618
Vaccines (Basel). 2014 Mar 25;2(2):196-215. doi: 10.3390/vaccines2020196.

DNA vaccine-induced immunity can be enhanced by the co-delivery of synthetic gene-encoding molecular adjuvants. Many of these adjuvants have included cytokines, chemokines or co-stimulatory molecules that have been demonstrated to enhance vaccine-induced immunity by increasing the magnitude or type...

Viral communities of the human gut: metagenomic analysis of composition and dynamics.

Mobile DNA

Aggarwala V, Liang G, Bushman FD.
PMID: 29026445
Mob DNA. 2017 Oct 03;8:12. doi: 10.1186/s13100-017-0095-y. eCollection 2017.

BACKGROUND: The numerically most abundant biological entities on Earth are viruses. Vast populations prey on the cellular microbiota in all habitats, including the human gut.MAIN BODY: Here we review approaches for studying the human virome, and some recent results...

Preventing Cryptococcosis-Shifting the Paradigm in the Era of Highly Active Antiretroviral Therapy.

Current tropical medicine reports

Meya D, Rajasingham R, Nalintya E, Tenforde M, Jarvis JN.
PMID: 25960942
Curr Trop Med Rep. 2015;2(2):81-89. doi: 10.1007/s40475-015-0045-z.

Cryptococcosis remains a significant cause of morbidity and mortality among HIV-infected patients, especially in sub-Saharan Africa where it causes up to 20 % of AIDS-related deaths in HIV programs. A new, highly sensitive, and affordable point of care diagnostic...

Invasive cervical cancers from women living in the United States or Botswana: differences in human papillomavirus type distribution.

Infectious agents and cancer

Ermel A, Ramogola-Masire D, Zetola N, Tong Y, Qadadri B, Azar MM, Brown DR.
PMID: 25053972
Infect Agent Cancer. 2014 Jul 08;9:22. doi: 10.1186/1750-9378-9-22. eCollection 2014.

BACKGROUND: Cervical cancer is the primary cause of cancer-related deaths in women living in Botswana.METHODS: Paraffin-embedded blocks of formalin-fixed invasive cervical cancer specimens were identified from women living in the U.S. (n = 50) or Botswana (n = 171)...

Erratum: Longer hospital stay is associated with high rates of tuberculosis-related morbidity and mortality within 12 months after discharge in a referral hospital in Sub-Saharan Africa.

BMC infectious diseases

Zetola NM, Macesic N, Shin SS, Peloso A, Ncube R, Klausner JD, Modongo C, Collman RG.
PMID: 25958311
BMC Infect Dis. 2015 May 10;15:211. doi: 10.1186/s12879-015-0942-8.

No abstract available.

A spatially varying two-sample recombinant coalescent, with applications to HIV escape response.

Advances in neural information processing systems

Braunstein A, Jensen ST, Wei Z, McAuliffe JD.
PMID: 20531976
Adv Neural Inf Process Syst. 2008;21:662.

Statistical evolutionary models provide an important mechanism for describing and understanding the escape response of a viral population under a particular therapy. We present a new hierarchical model that incorporates spatially varying mutation and recombination rates at the nucleotide...

A COMPARATIVE EVALUATION OF TWO INTERVENTIONS FOR EDUCATOR TRAINING IN HIV/AIDS IN SOUTH AFRICA.

International journal of education and development using information and communication technology

Chao LW, Gow J, Akintola O, Pauly MV.
PMID: 20852677
Int J Educ Dev Using Inf Commun Technol. 2010 Jan 01;6(1):1-14. doi: 10.4018/jicte.2010091101.

The purpose of this study was to compare two different methods to teach educators about HIV/AIDS. Sixty educators were selected from eight schools in KwaZulu-Natal Province, South Africa, to undergo HIV/AIDS training using an interactive CD-ROM intervention. Another sixty...

A Simple PCR-RFLP Method for Genetic Phase Determination in Compound Heterozygotes.

Frontiers in genetics

Perry RT, Dwivedi H, Aissani B.
PMID: 22303402
Front Genet. 2012 Jan 13;2:108. doi: 10.3389/fgene.2011.00108. eCollection 2011.

When susceptibility to diseases is caused by cis-effects of multiple alleles at adjacent polymorphic sites, it may be difficult to assess with confidence the genetic phase and identify individuals carrying the risk haplotype. Experimental assessment of genetic phase is...

Physical attractiveness and women's HIV risk in rural Malawi.

Demographic research

Frye M, Chae S.
PMID: 29242708
Demogr Res. 2017;37:251-294. doi: 10.4054/DemRes.2017.37.10. Epub 2017 Aug 08.

BACKGROUND: Qualitative evidence from sub-Saharan Africa, where a generalized AIDS epidemic exists, suggests that attractiveness may play a role in shaping individual-level HIV risk. Attractive women, who are often blamed for the epidemic and stigmatized, are believed to pose...

Predicting Risk of End-Stage Liver Disease in Antiretroviral-Treated Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Patients.

Open forum infectious diseases

Lo Re V, Kallan MJ, Tate JP, Lim JK, Goetz MB, Klein MB, Rimland D, Rodriguez-Barradas MC, Butt AA, Gibert CL, Brown ST, Park LS, Dubrow R, Reddy KR, Kostman JR, Justice AC, Localio AR.
PMID: 26284259
Open Forum Infect Dis. 2015 Jul 09;2(3):ofv109. doi: 10.1093/ofid/ofv109. eCollection 2015 Sep.

Background.  End-stage liver disease (ESLD) is an important cause of morbidity among human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-coinfected patients. Quantifying the risk of this outcome over time could help determine which coinfected patients should be targeted for risk...

Health Promotion: Results of focus groups with African-American men.

Journal of men's health

Heeren GA, Jemmott JB.
PMID: 21566707
J Mens Health. 2011 Mar 01;8(1):50-55. doi: 10.1016/j.jomh.2010.11.002.

BACKGROUND: Almost half (49%) of the people diagnosed with HIV/AIDS in the United States (US) are African-Americans. Although African-Americans represent only about 13% of the overall population, they continue to account for a higher proportion of cases at all...

Improved Expansion and .

Molecular therapy. Methods & clinical development

Medvec AR, Ecker C, Kong H, Winters EA, Glover J, Varela-Rohena A, Riley JL.
PMID: 29687031
Mol Ther Methods Clin Dev. 2017 Nov 07;8:65-74. doi: 10.1016/j.omtm.2017.11.001. eCollection 2018 Mar 16.

Improvements to T cell culture systems that promote long-term engraftment and function of adoptively transferred T cells will likely result in superior clinical benefit to more individuals. To this end, we recently developed a chemically defined cell culture medium...

Showing 1 to 12 of 97 entries