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Showing 1 to 12 of 89 entries
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Human Papillomavirus at Multiple Sites Associated with Anal Squamous Intraepithelial Lesions in HIV-Seropositive Individuals.

Annals of clinical cytology and pathology

Chuang E, Lim E, Milne C, Zhu X, Agsalda M, Killeen J, Miller FD, Hernandez BY, Shiramizu B.
PMID: 28042618
Ann Clin Cytol Pathol. 2016;2(4). Epub 2016 Jul 12.

OBJECTIVE: HIV-Seropositive patients have higher risk of HPV infection even on anti-retroviral therapy. Infection with high-risk HPV genotypes can cause dysplasia leading to cancer. This study assessed HPV at different anatomical sites in HIV-seropositive individuals and factors associated with...

Ursodeoxycholic Acid Alters Bile Acid and Fatty Acid Profiles in a Mouse Model of Diet-Induced Obesity.

Frontiers in pharmacology

Zhang Y, Zheng X, Huang F, Zhao A, Ge K, Zhao Q, Jia W.
PMID: 31402868
Front Pharmacol. 2019 Jul 25;10:842. doi: 10.3389/fphar.2019.00842. eCollection 2019.

Ursodeoxycholic acid (UDCA) is a bile acid (BA) approved by the U.S. Food and Drug Administration for the treatment of primary biliary cholangitis. It is also the major active component of bear bile used in traditional Chinese medicine to...

Linker Variation and Structure-Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors.

ACS medicinal chemistry letters

Lopez-Tapia F, Brotherton-Pleiss C, Yue P, Murakami H, Costa Araujo AC, Reis Dos Santos B, Ichinotsubo E, Rabkin A, Shah R, Lantz M, Chen S, Tius MA, Turkson J.
PMID: 29541369
ACS Med Chem Lett. 2018 Feb 16;9(3):250-255. doi: 10.1021/acsmedchemlett.7b00544. eCollection 2018 Mar 08.

The molecular determinants for the activities of the reported benzoic acid (SH4-54), salicylic acid (BP-1-102), and benzohydroxamic acid (SH5-07)-based STAT3 inhibitors were investigated to design optimized analogues. All three leads are based on an

Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis.

Oncotarget

Marciel MP, Khadka VS, Deng Y, Kilicaslan P, Pham A, Bertino P, Lee K, Chen S, Glibetic N, Hoffmann FW, Matter ML, Hoffmann PR.
PMID: 29568366
Oncotarget. 2018 Feb 03;9(17):13407-13422. doi: 10.18632/oncotarget.24388. eCollection 2018 Mar 02.

Interest has emerged in the therapeutic potential of inhibiting store operated calcium (Ca

Late recurrence of hepatocellular carcinoma after liver transplantation.

Hepatoma research

Zhang JA, Kwee SA, Wong LL.
PMID: 28966983
Hepatoma Res. 2017;3:58-66. doi: 10.20517/2394-5079.2017.05. Epub 2017 Apr 10.

AIMS: Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and liver transplant (LT) prolongs survival. However, 15-20% will experience recurrent HCC, most occurring within 2 years of LT. HCC patients with late recurrences (>5 years...

Individual-Level and Ecological Studies.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Wills TA, Soneji SS.
PMID: 29709223
J Adolesc Health. 2018 May;62(5):507-508. doi: 10.1016/j.jadohealth.2018.03.002.

No abstract available.

Comparison of Commercial ELISA Kits, a Prototype Multiplex Electrochemoluminescent Assay, and a Multiplex Bead-Based Immunoassay for Detecting a Urine-Based Bladder-Cancer-Associated Diagnostic Signature.

Diagnostics (Basel, Switzerland)

Furuya H, Pagano I, Chee K, Kobayashi T, Wong RS, Lee R, Rosser CJ.
PMID: 31671775
Diagnostics (Basel). 2019 Oct 29;9(4). doi: 10.3390/diagnostics9040166.

The ability to accurately measure multiple proteins simultaneously in a single assay has the potential to markedly improve the efficiency of clinical tests composed of multiple biomarkers. We investigated the diagnostic accuracy of the two multiplex protein array platforms...

Rationale and design of a randomized, controlled, superiority trial on areca nut/betel quid cessation: The Betel Nut Intervention Trial (BENIT).

Contemporary clinical trials communications

Paulino YC, Wilkens LR, Sotto PP, Franke AA, Kawamoto CT, Chennaux JSN, Mendez AJ, Tenorio LF, Badowski G, Pokhrel P, Herzog TA.
PMID: 32154430
Contemp Clin Trials Commun. 2020 Feb 21;17:100544. doi: 10.1016/j.conctc.2020.100544. eCollection 2020 Mar.

BACKGROUND: Areca nut (AN) is the seed endosperm of the METHODS/DESIGN: The Betel Nut Intervention Trial (BENIT; trial #NCT02942745) is a randomized controlled trial designed to test the efficacy of an intensive AN/BQ cessation program. The trial is ongoing...

Mediators of a 12-month change in physical activity in ethnically diverse sample of postpartum women.

Translational journal of the American College of Sports Medicine

Albright CL, Wilkens LR, Saiki K, White KK, Steffen AD.
PMID: 31984225
Transl J Am Coll Sports Med. 2019 Oct;4(19):215-224. doi: 10.1249/TJX.0000000000000106.

PURPOSE: Understanding theoretically derived social and behavioral mediators of long-term increases in physical activity (PA) in a vulnerable population at risk for being underactive is needed to inform future research, clinical applications, and public health efforts. This is an...

Vitamin D deficiency and insufficiency in Hawaii: Levels and sources of serum vitamin D in older adults.

American journal of human biology : the official journal of the Human Biology Council

Oshiro CE, Hillier TA, Edmonds G, Peterson M, Hill PL, Hampson S.
PMID: 34213035
Am J Hum Biol. 2021 Jul 02;e23636. doi: 10.1002/ajhb.23636. Epub 2021 Jul 02.

OBJECTIVE: To examine the major sources of vitamin D [25-hydroxyvitamin D (25(OH)D)] and evaluate their collective role on rates of vitamin D deficiency/insufficiency among older adults.METHODS: Cross-sectional analysis of the relationship between serum 25(OH)D levels and sources of vitamin...

Concurrent Use of E-cigarettes, Combustible Cigarettes, and Marijuana.

Pediatrics

Wills TA, Leventhal AM, Sargent JD, Pagano I.
PMID: 34584003
Pediatrics. 2021 Oct;148(4). doi: 10.1542/peds.2021-050749. Epub 2021 Sep 28.

OBJECTIVE: Subgroups of adolescent single and dual e-cigarette and cigarette users have been identified, but usage patterns have changed in recent years, and there has been an increase in marijuana use. Research is needed with current data to identify...

Diverse roles of EV-RNA in cancer progression.

Seminars in cancer biology

Cocks A, Martinez-Rodriguez V, Del Vecchio F, Schukking M, Broseghini E, Giannakopoulos S, Fabbri M.
PMID: 33440245
Semin Cancer Biol. 2021 Oct;75:127-135. doi: 10.1016/j.semcancer.2020.11.022. Epub 2021 Jan 10.

Extracellular vesicles (EVs) have emerged as important players in all aspects of cancer biology. Their function is mediated by their cargo and surface molecules including proteins, lipids, sugars and nucleic acids. RNA in particular is a key mediator of...

Showing 1 to 12 of 89 entries