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Showing 1 to 12 of 14 entries
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A second generation MRI contrast agent for imaging zinc ions .

MedChemComm

De León-Rodríguez LM, Lubag AJ, López JA, Andreu-de-Riquer G, Alvarado-Monzón JC, Sherry AD.
PMID: 24013159
Medchemcomm. 2012 Apr 01;3(4):480-483. doi: 10.1039/C2MD00301E.

A Zn

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De León-Rodríguez LM, Lubag AJ, López JA, et al. A second generation MRI contrast agent for imaging zinc ions . Medchemcomm. 2012;3(4):480-483doi: 10.1039/C2MD00301E.
De León-Rodríguez, L. M., Lubag, A. J., López, J. A., Andreu-de-Riquer, G., Alvarado-Monzón, J. C., & Sherry, A. D. (2012). A second generation MRI contrast agent for imaging zinc ions . MedChemComm, 3(4), 480-483. https://doi.org/10.1039/C2MD00301E
De León-Rodríguez, Luis M, et al. "A second generation MRI contrast agent for imaging zinc ions ." MedChemComm vol. 3,4 (2012): 480-483. doi: https://doi.org/10.1039/C2MD00301E
De León-Rodríguez LM, Lubag AJ, López JA, Andreu-de-Riquer G, Alvarado-Monzón JC, Sherry AD. A second generation MRI contrast agent for imaging zinc ions . Medchemcomm. 2012 Apr 01;3(4):480-483. doi: 10.1039/C2MD00301E. PMID: 24013159; PMCID: PMC3763856.
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Imaging free zinc levels in vivo - what can be learned?.

Inorganica chimica acta

De Leon-Rodriguez L, Lubag AJ, Sherry AD.
PMID: 23180883
Inorganica Chim Acta. 2012 Dec 01;393:12-23. doi: 10.1016/j.ica.2012.06.026. Epub 2012 Jun 25.

Our ever-expanding knowledge about the role of zinc in biology includes its role in redox modulation, immune response, neurotransmission, reproduction, diabetes, cancer, and Alzheimers disease is galvanizing interest in detecting and monitoring the various forms of Zn(II) in biological...

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De Leon-Rodriguez L, Lubag AJ, Sherry AD. Imaging free zinc levels in vivo - what can be learned?. Inorganica Chim Acta. 2012;393:12-23doi: 10.1016/j.ica.2012.06.026.
De Leon-Rodriguez, L., Lubag, A. J., & Sherry, A. D. (2012). Imaging free zinc levels in vivo - what can be learned?. Inorganica chimica acta, 39312-23. https://doi.org/10.1016/j.ica.2012.06.026
De Leon-Rodriguez, Luis, et al. "Imaging free zinc levels in vivo - what can be learned?." Inorganica chimica acta vol. 393 (2012): 12-23. doi: https://doi.org/10.1016/j.ica.2012.06.026
De Leon-Rodriguez L, Lubag AJ, Sherry AD. Imaging free zinc levels in vivo - what can be learned?. Inorganica Chim Acta. 2012 Dec 01;393:12-23. doi: 10.1016/j.ica.2012.06.026. Epub 2012 Jun 25. PMID: 23180883; PMCID: PMC3501686.
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The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy.

RSC advances

Lumata L, Merritt M, Khemtong C, Ratnakar SJ, van Tol J, Yu L, Song L, Kovacs Z.
PMID: 23205273
RSC Adv. 2012 Jan 01;2(33):12812-12817. doi: 10.1039/C2RA21853D. Epub 2012 Oct 25.

The free radical 2,2-diphenyl-1-pycrylhydrazyl (DPPH) was tested as a polarising agent for fast dissolution dynamic nuclear polarisation (DNP) NMR spectroscopy. DPPH was found to be reasonably soluble in sulfolane and the optimum concentration for DNP is 20-40 mM depending...

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Lumata L, Merritt M, Khemtong C, et al. The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy. RSC Adv. 2012;2(33):12812-12817doi: 10.1039/C2RA21853D.
Lumata, L., Merritt, M., Khemtong, C., Ratnakar, S. J., van Tol, J., Yu, L., Song, L., & Kovacs, Z. (2012). The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy. RSC advances, 2(33), 12812-12817. https://doi.org/10.1039/C2RA21853D
Lumata, Lloyd, et al. "The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy." RSC advances vol. 2,33 (2012): 12812-12817. doi: https://doi.org/10.1039/C2RA21853D
Lumata L, Merritt M, Khemtong C, Ratnakar SJ, van Tol J, Yu L, Song L, Kovacs Z. The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy. RSC Adv. 2012 Jan 01;2(33):12812-12817. doi: 10.1039/C2RA21853D. Epub 2012 Oct 25. PMID: 23205273; PMCID: PMC3507463.
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Novel Fe.

ChemPlusChem

Yu JX, Gulaka PK, Liu L, Kodibagkar VD, Mason RP.
PMID: 23807909
Chempluschem. 2012 May 01;77(5):370-378. doi: 10.1002/cplu.201100072.

There is increasing interest in the development of reporter agents to reveal enzyme activity

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Yu JX, Gulaka PK, Liu L, et al. Novel Fe. Chempluschem. 2012;77(5):370-378doi: 10.1002/cplu.201100072.
Yu, J. X., Gulaka, P. K., Liu, L., Kodibagkar, V. D., & Mason, R. P. (2012). Novel Fe. ChemPlusChem, 77(5), 370-378. https://doi.org/10.1002/cplu.201100072
Yu, Jian-Xin, et al. "Novel Fe." ChemPlusChem vol. 77,5 (2012): 370-378. doi: https://doi.org/10.1002/cplu.201100072
Yu JX, Gulaka PK, Liu L, Kodibagkar VD, Mason RP. Novel Fe. Chempluschem. 2012 May 01;77(5):370-378. doi: 10.1002/cplu.201100072. PMID: 23807909; PMCID: PMC3691858.
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The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized .

Chemistry (Weinheim an der Bergstrasse, Germany)

Xing Y, Jindal AK, Regueiro-Figueroa M, Le Fur M, Kervarec N, Zhao P, Kovacs Z, Valencia L, Pérez-Lourido P, Tripier R, Esteban-Gómez D, Platas-Iglesias C, Sherry AD.
PMID: 27723138
Chemistry. 2016 Nov 07;22(46):16657-16667. doi: 10.1002/chem.201602901. Epub 2016 Oct 10.

Recently developed dynamic nuclear polarization (DNP) technology offers the potential of increasing the NMR sensitivity of even rare nuclei for biological imaging applications. Hyperpolarized

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Xing Y, Jindal AK, Regueiro-Figueroa M, et al. The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized . Chemistry. 2016;22(46):16657-16667doi: 10.1002/chem.201602901.
Xing, Y., Jindal, A. K., Regueiro-Figueroa, M., Le Fur, M., Kervarec, N., Zhao, P., Kovacs, Z., Valencia, L., Pérez-Lourido, P., Tripier, R., Esteban-Gómez, D., Platas-Iglesias, C., & Sherry, A. D. (2016). The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized . Chemistry (Weinheim an der Bergstrasse, Germany), 22(46), 16657-16667. https://doi.org/10.1002/chem.201602901
Xing, Yixun, et al. "The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized ." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 22,46 (2016): 16657-16667. doi: https://doi.org/10.1002/chem.201602901
Xing Y, Jindal AK, Regueiro-Figueroa M, Le Fur M, Kervarec N, Zhao P, Kovacs Z, Valencia L, Pérez-Lourido P, Tripier R, Esteban-Gómez D, Platas-Iglesias C, Sherry AD. The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized . Chemistry. 2016 Nov 07;22(46):16657-16667. doi: 10.1002/chem.201602901. Epub 2016 Oct 10. PMID: 27723138; PMCID: PMC5308128.
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On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands.

Current protocols in chemical biology

Udugamasooriya DG, Kodadek T.
PMID: 22582145
Curr Protoc Chem Biol. 2012 Mar;4:35-48. doi: 10.1002/9780470559277.ch110199. Epub 2012 Mar 01.

Combinatorial library screens can identify a suitable ligand for a biological target of interest out of thousands or even millions of compounds, and can play a key role in the modern drug development process. While conventional high-throughput cell screens...

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Udugamasooriya DG, Kodadek T. On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Curr Protoc Chem Biol. 2012;4:35-48doi: 10.1002/9780470559277.ch110199.
Udugamasooriya, D. G., & Kodadek, T. (2012). On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Current protocols in chemical biology, 435-48. https://doi.org/10.1002/9780470559277.ch110199
Udugamasooriya, D Gomika, and Kodadek, Thomas. "On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands." Current protocols in chemical biology vol. 4 (2012): 35-48. doi: https://doi.org/10.1002/9780470559277.ch110199
Udugamasooriya DG, Kodadek T. On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Curr Protoc Chem Biol. 2012 Mar;4:35-48. doi: 10.1002/9780470559277.ch110199. Epub 2012 Mar 01. PMID: 22582145; PMCID: PMC3348698.
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Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models.

Metabolites

Sun J, Bok RA, DeLos Santos J, Upadhyay D, DeLos Santos R, Agarwal S, Van Criekinge M, Vigneron DB, Aggarwal R, Peehl DM, Kurhanewicz J, Sriram R.
PMID: 33652703
Metabolites. 2021 Feb 26;11(3). doi: 10.3390/metabo11030139.

Currently, no clinical methods reliably predict the development of castration-resistant prostate cancer (CRPC) that occurs almost universally in men undergoing androgen deprivation therapy. Hyperpolarized (HP)

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Sun J, Bok RA, DeLos Santos J, et al. Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models. Metabolites. 2021;11(3)doi: 10.3390/metabo11030139.
Sun, J., Bok, R. A., DeLos Santos, J., Upadhyay, D., DeLos Santos, R., Agarwal, S., Van Criekinge, M., Vigneron, D. B., Aggarwal, R., Peehl, D. M., Kurhanewicz, J., & Sriram, R. (2021). Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models. Metabolites, 11(3), . https://doi.org/10.3390/metabo11030139
Sun, Jinny, et al. "Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models." Metabolites vol. 11,3 (2021). doi: https://doi.org/10.3390/metabo11030139
Sun J, Bok RA, DeLos Santos J, Upadhyay D, DeLos Santos R, Agarwal S, Van Criekinge M, Vigneron DB, Aggarwal R, Peehl DM, Kurhanewicz J, Sriram R. Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models. Metabolites. 2021 Feb 26;11(3). doi: 10.3390/metabo11030139. PMID: 33652703; PMCID: PMC7996870.
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Toward the Design of MR Agents for Imaging β-Cell Function.

Current medicinal chemistry. Immunology, endocrine & metabolic agents

Woods M, Zhang S, Sherry AD.
PMID: 20686642
Curr Med Chem Immunol Endocr Metab Agents. 2004 Dec;4(4):349-369. doi: 10.2174/1568013043357338.

The chemistry of Gd(3+)-based MRI agents has advanced considerably during the past decade toward agents with higher relaxivity and agents that respond to physiology and/or metabolism. This review describes various approaches that have been taken toward the development of...

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Woods M, Zhang S, Sherry AD. Toward the Design of MR Agents for Imaging β-Cell Function. Curr Med Chem Immunol Endocr Metab Agents. 2004;4(4):349-369doi: 10.2174/1568013043357338.
Woods, M., Zhang, S., & Sherry, A. D. (2004). Toward the Design of MR Agents for Imaging β-Cell Function. Current medicinal chemistry. Immunology, endocrine & metabolic agents, 4(4), 349-369. https://doi.org/10.2174/1568013043357338
Woods, Mark, et al. "Toward the Design of MR Agents for Imaging β-Cell Function." Current medicinal chemistry. Immunology, endocrine & metabolic agents vol. 4,4 (2004): 349-369. doi: https://doi.org/10.2174/1568013043357338
Woods M, Zhang S, Sherry AD. Toward the Design of MR Agents for Imaging β-Cell Function. Curr Med Chem Immunol Endocr Metab Agents. 2004 Dec;4(4):349-369. doi: 10.2174/1568013043357338. PMID: 20686642; PMCID: PMC2913624.
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Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model.

Translational oncology

Zhao D, Stafford JH, Zhou H, Thorpe PE.
PMID: 22191000
Transl Oncol. 2011 Dec;4(6):355-64. doi: 10.1593/tlo.11178. Epub 2011 Dec 01.

Phosphatidylserine (PS) is normally intracellular but becomes exposed on the luminal surface of vascular endothelial cells in tumors. It also becomes exposed on tumors cells responding to therapy. In the present study, we optically imaged exposed PS in vivo...

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Zhao D, Stafford JH, Zhou H, et al. Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model. Transl Oncol. 2011;4(6):355-64doi: 10.1593/tlo.11178.
Zhao, D., Stafford, J. H., Zhou, H., & Thorpe, P. E. (2011). Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model. Translational oncology, 4(6), 355-64. https://doi.org/10.1593/tlo.11178
Zhao, Dawen, et al. "Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model." Translational oncology vol. 4,6 (2011): 355-64. doi: https://doi.org/10.1593/tlo.11178
Zhao D, Stafford JH, Zhou H, Thorpe PE. Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model. Transl Oncol. 2011 Dec;4(6):355-64. doi: 10.1593/tlo.11178. Epub 2011 Dec 01. PMID: 22191000; PMCID: PMC3243659.
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Multifunctional Polymeric Scaffolds for Enhancement of PARACEST Contrast Sensitivity and Performance: The Effects of Random Copolymer Variations.

Macromolecules

Wu Y, Zhao P, Kiefer GE, Sherry AD.
PMID: 20838469
Macromolecules. 2010 Aug 24;43(16):6616-6624. doi: 10.1021/ma100776d.

A DOTA (1,4,7,10-tetraazacyclododecane-N,N',N",N'"-tetraacetic acid) tetraamide ligand having a single acrylamide side-chain (M1) was copolymerized with either 2-methylacrylic acid (MAA), 2-(acryloylamino)-2-methyl-1-propanesulfonic acid (AMPS) or N-isopropylacrylamide (NIPAM) to create a series of linear random copolymers using classical free radical chain polymerization...

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Wu Y, Zhao P, Kiefer GE, et al. Multifunctional Polymeric Scaffolds for Enhancement of PARACEST Contrast Sensitivity and Performance: The Effects of Random Copolymer Variations. Macromolecules. 2010;43(16):6616-6624doi: 10.1021/ma100776d.
Wu, Y., Zhao, P., Kiefer, G. E., & Sherry, A. D. (2010). Multifunctional Polymeric Scaffolds for Enhancement of PARACEST Contrast Sensitivity and Performance: The Effects of Random Copolymer Variations. Macromolecules, 43(16), 6616-6624. https://doi.org/10.1021/ma100776d
Wu, Yunkou, et al. "Multifunctional Polymeric Scaffolds for Enhancement of PARACEST Contrast Sensitivity and Performance: The Effects of Random Copolymer Variations." Macromolecules vol. 43,16 (2010): 6616-6624. doi: https://doi.org/10.1021/ma100776d
Wu Y, Zhao P, Kiefer GE, Sherry AD. Multifunctional Polymeric Scaffolds for Enhancement of PARACEST Contrast Sensitivity and Performance: The Effects of Random Copolymer Variations. Macromolecules. 2010 Aug 24;43(16):6616-6624. doi: 10.1021/ma100776d. PMID: 20838469; PMCID: PMC2936783.
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Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI.

Theranostics

Kessinger CW, Togao O, Khemtong C, Huang G, Takahashi M, Gao J.
PMID: 21562632
Theranostics. 2011 Apr 24;1:263-73. doi: 10.7150/thno/v01p0263.

Nanoparticulate imaging probes have become an increasingly important arsenal in the visualization of molecular markers for early diagnosis and post-therapy assessment of diseases. Surface functionalization of these nanoparticles has led to the development of a variety of targeted nanoprobes...

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Kessinger CW, Togao O, Khemtong C, et al. Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI. Theranostics. 2011;1:263-73doi: 10.7150/thno/v01p0263.
Kessinger, C. W., Togao, O., Khemtong, C., Huang, G., Takahashi, M., & Gao, J. (2011). Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI. Theranostics, 1263-73. https://doi.org/10.7150/thno/v01p0263
Kessinger, Chase W, et al. "Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI." Theranostics vol. 1 (2011): 263-73. doi: https://doi.org/10.7150/thno/v01p0263
Kessinger CW, Togao O, Khemtong C, Huang G, Takahashi M, Gao J. Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI. Theranostics. 2011 Apr 24;1:263-73. doi: 10.7150/thno/v01p0263. PMID: 21562632; PMCID: PMC3092449.
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Synthesis and Characterization of DOTA-(amide)(4) Derivatives: Equilibrium and Kinetic Behavior of Their Lanthanide(III) Complexes.

European journal of inorganic chemistry

Pasha A, Tircsó G, Benyó ET, Brücher E, Sherry AD.
PMID: 19802361
Eur J Inorg Chem. 2007 Jul 31;2007(27):4340-4349. doi: 10.1002/ejic.200700354.

Lanthanide complexes of tetraamide derivatives of DOTA are of interest today because of their application as chemical exchange saturation transfer (CEST) agents for magnetic resonance imaging (MRI). The protonation constants of some simple tetraamide derivatives of DOTA and the...

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Pasha A, Tircsó G, Benyó ET, et al. Synthesis and Characterization of DOTA-(amide)(4) Derivatives: Equilibrium and Kinetic Behavior of Their Lanthanide(III) Complexes. Eur J Inorg Chem. 2007;2007(27):4340-4349doi: 10.1002/ejic.200700354.
Pasha, A., Tircsó, G., Benyó, E. T., Brücher, E., & Sherry, A. D. (2007). Synthesis and Characterization of DOTA-(amide)(4) Derivatives: Equilibrium and Kinetic Behavior of Their Lanthanide(III) Complexes. European journal of inorganic chemistry, 2007(27), 4340-4349. https://doi.org/10.1002/ejic.200700354
Pasha, Azhar, et al. "Synthesis and Characterization of DOTA-(amide)(4) Derivatives: Equilibrium and Kinetic Behavior of Their Lanthanide(III) Complexes." European journal of inorganic chemistry vol. 2007,27 (2007): 4340-4349. doi: https://doi.org/10.1002/ejic.200700354
Pasha A, Tircsó G, Benyó ET, Brücher E, Sherry AD. Synthesis and Characterization of DOTA-(amide)(4) Derivatives: Equilibrium and Kinetic Behavior of Their Lanthanide(III) Complexes. Eur J Inorg Chem. 2007 Jul 31;2007(27):4340-4349. doi: 10.1002/ejic.200700354. PMID: 19802361; PMCID: PMC2756095.
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Showing 1 to 12 of 14 entries