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Showing 1 to 4 of 4 entries
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Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays.

Microarrays (Basel, Switzerland)

Rantala JK, Kwon S, Korkola J, Gray JW.
PMID: 27605183
Microarrays (Basel). 2013 Apr 11;2(2):97-114. doi: 10.3390/microarrays2020097.

Over the past decade, great strides have been made in identifying gene aberrations and deregulated pathways that are associated with specific disease states. These association studies guide experimental studies aimed at identifying the aberrant genes and networks that cause...

Magellan: a web based system for the integrated analysis of heterogeneous biological data and annotations; application to DNA copy number and expression data in ovarian cancer.

Cancer informatics

Kingsley CB, Kuo WL, Polikoff D, Berchuck A, Gray JW, Jain AN.
PMID: 19458754
Cancer Inform. 2007 Feb 05;2:10-21.

Recent advances in high throughput biological methods allow researchers to generate enormous amounts of data from a single experiment. In order to extract meaningful conclusions from this tidal wave of data, it will be necessary to develop analytical methods...

Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions.

International journal of proteomics

Held JM, Schilling B, D'Souza AK, Srinivasan T, Behring JB, Sorensen DJ, Benz CC, Gibson BW.
PMID: 23710360
Int J Proteomics. 2013;2013:791985. doi: 10.1155/2013/791985. Epub 2013 Apr 04.

The receptor tyrosine kinase ErbB2 is a breast cancer biomarker whose posttranslational modifications (PTMs) are a key indicator of its activation. Quantifying the expression and PTMs of biomarkers such as ErbB2 by selected reaction monitoring (SRM) mass spectrometry has...

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays.

BMC medical genomics

Wang Y, Carlton VE, Karlin-Neumann G, Sapolsky R, Zhang L, Moorhead M, Wang ZC, Richardson AL, Warren R, Walther A, Bondy M, Sahin A, Krahe R, Tuna M, Thompson PA, Spellman PT, Gray JW, Mills GB, Faham M.
PMID: 19228381
BMC Med Genomics. 2009 Feb 19;2:8. doi: 10.1186/1755-8794-2-8.

BACKGROUND: A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high failure rates compared...

Showing 1 to 4 of 4 entries