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Showing 1 to 12 of 6222 entries
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Dynamics of two-color two-photon excited fluorescence of p-terphenyl: determination and analysis of the molecular parameters.

The journal of physical chemistry. A

Denicke S, Gericke KH, Smolin AG, Shternin PS, Vasyutinskii OS.
PMID: 20722449
J Phys Chem A. 2010 Sep 16;114(36):9681-92. doi: 10.1021/jp101403x.

We present the experimental and theoretical study of the two-photon excited polarized fluorescence of p-terphenyl dissolved in cyclohexane/paraffin. The fluorescence was produced within a two-color two-photon (2C2P) excitation scheme utilizing simultaneous absorption of two femtosecond laser pulses at 400...

Analyzing historical trends in breast cancer biomarker expression: a feasibility study (1947-2009).

NPJ breast cancer

Krieger N, Habel LA, Waterman PD, Shabani M, Ellison-Loschmann L, Achacoso NS, Acton L, Schnitt SJ.
PMID: 26807440
NPJ Breast Cancer. 2015;1. doi: 10.1038/npjbcancer.2015.16. Epub 2015 Oct 07.

BACKGROUND/OBJECTIVES: Determining long-term trends in tumor biomarker expression is essential for understanding aspects of tumor biology amenable to change. Limiting the availability of such data, currently used assays for biomarkers are relatively new. For example, assays for the estrogen...

Application of a novel and automated branched DNA in situ hybridization method for the rapid and sensitive localization of mRNA molecules in plant tissues.

Applications in plant sciences

Bowling AJ, Pence HE, Church JB.
PMID: 25202621
Appl Plant Sci. 2014 Apr 03;2(4). doi: 10.3732/apps.1400011. eCollection 2014 Apr.

PREMISE OF THE STUDY: A novel branched DNA detection technology, RNAscope in situ hybridization (ISH), originally developed for use on human clinical and animal tissues, was adapted for use in plant tissue in an attempt to overcome some of...

High-contrast enzymatic immunohistochemistry of pigmented tissues.

Journal of biological methods

Duncan SM, Seigel GM.
PMID: 27660801
J Biol Methods. 2016;3(3). doi: 10.14440/jbm.2016.122. Epub 2016 Jul 12.

Historically, standard enzyme immunohistochemistry has been accomplished with brown (DAB, diaminobenzidine) substrate. This can become problematic in pigmented tissues, such as the retina, where brown pigment of retinal pigmented epithelial (RPE) cells can be easily confounded with brown substrate....

Expression of family with sequence similarity 172 member A and nucleotide-binding protein 1 is associated with the poor prognosis of colorectal carcinoma.

Oncology letters

Liu W, Wang S, Qian K, Zhang J, Zhang Z, Liu H.
PMID: 28927116
Oncol Lett. 2017 Sep;14(3):3587-3593. doi: 10.3892/ol.2017.6585. Epub 2017 Jul 15.

In our previous studies, a functionally unknown gene, family with sequence similarity 172, member A (FAM172A), was identified. High levels of FAM172A suppressed the cell cycle process, arresting HepG2 cells in G1/S and inhibiting cell proliferation. The present study...

Predictive value of molecular subtyping in NMIBC by RT-qPCR of ERBB2, ESR1, PGR and MKI67 from formalin fixed TUR biopsies.

Oncotarget

Breyer J, Wirtz RM, Otto W, Laible M, Schlombs K, Erben P, Kriegmair MC, Stoehr R, Eidt S, Denzinger S, Burger M, Hartmann A.
PMID: 28978063
Oncotarget. 2017 Jun 28;8(40):67684-67695. doi: 10.18632/oncotarget.18804. eCollection 2017 Sep 15.

Expression of ESR1, PGR, HER2 and Ki67 is important for risk stratification and therapy in breast cancer. Hormone receptor expression can also be found in MIBC, reflecting luminal and basal subtypes of breast cancer. Thus the purpose was to...

Loss of heterozygosity and microsatellite instability as predictive markers among Iranian esophageal cancer patients.

Iranian journal of basic medical sciences

Forghanifard MM, Vahid EE, Dadkhah E, Gholamin M, Noghabi SB, Ghahraman M, Farzadnia M, Abbaszadegan MR.
PMID: 27635196
Iran J Basic Med Sci. 2016 Jul;19(7):726-33.

OBJECTIVES: Variation in microsatellite sequences that are dispersed in the genome has been linked to a deficiency in cellular mismatch repair system and defects in several genes of this system are involved in carcinogenesis. Our aim in this study...

Sun-tracking optical element realized using thermally activated transparency-switching material.

Optics express

Apostoleris H, Stefancich M, Lilliu S, Chiesa M.
PMID: 26367692
Opt Express. 2015 Jul 27;23(15):A930-5. doi: 10.1364/OE.23.00A930.

We present a proof of concept demonstration of a novel optical element: a light-responsive aperture that can track a moving light beam. The element is created using a thermally-activated transparency-switching material composed of paraffin wax and polydimethylsiloxane (PDMS). Illumination...

Expression of GLP-1 receptor and CD26 in human thyroid C-cells: The association of thyroid C-cell tumorigenesis with incretin-based medicine.

Oncology letters

Song Y, Zhou M, Cao Y, Qi J, Geng J, Liu X.
PMID: 28454451
Oncol Lett. 2017 Apr;13(4):2684-2690. doi: 10.3892/ol.2017.5752. Epub 2017 Feb 20.

Recent reports have demonstrated that long-term and high dosage treatments with incretin-based medicine, such as hormone glucagon-like peptide-1 (GLP-1) may induce thyroid C-cell pathological changes in rodents, rather than in humans. Doubts regarding the tumorigenic potential of GLP-1 analogues...

Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies.

Cancers

Chen H, Luthra R, Goswami RS, Singh RR, Roy-Chowdhuri S.
PMID: 26343728
Cancers (Basel). 2015 Aug 28;7(3):1699-715. doi: 10.3390/cancers7030859.

Application of next-generation sequencing (NGS) technology to routine clinical practice has enabled characterization of personalized cancer genomes to identify patients likely to have a response to targeted therapy. The proper selection of tumor sample for downstream NGS based mutational...

Studies on the relationship between the point mutation of ras oncogenes and the prognosis of patients with gastric cancer.

World journal of gastroenterology

Fang DC, Luo YH, Lu R, Liu WW.
PMID: 27006577
World J Gastroenterol. 1997 Mar 15;3(1):19-21. doi: 10.3748/wjg.v3.i1.19.

AIM: To study the relationship between the point mutation of ras oncogenes and the prognosis of patients with gastric cancer.METHODS: The point mutations at codon 12 and 61 of c-Ha-ras, at codon 12 and 13 of K-ras, and at...

[Preliminary research of Er:YAG laser used for pulpotomy of Beagle dogs].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

Guo YD, Zhang S.
PMID: 27538158
Beijing Da Xue Xue Bao Yi Xue Ban. 2016 Feb 18;48(1):714-9.

OBJECTIVE: To investigate the effects of erbium:yttrium aluminium garnet (Er:YAG)laser irradiation on pulp and formation of dentin bridge. The beagle dogs' coronal pulp is amputated by Er:YAG laser.METHODS: In the study, 24 premolar teeth of two one-year-old Beagle dogs...

Showing 1 to 12 of 6222 entries