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Transforming drug discovery and development through innovation: past, present and future.

Bioanalysis

Needham S, Premkumar N, Pols J, Lee M.
PMID: 23394693
Bioanalysis. 2013 Feb;5(3):275-9. doi: 10.4155/bio.12.320.

This annual meeting began in 1998 and was the first industry-led event to focus on the specific needs of industry researchers. The goal of Clinical and Pharmaceutical Solutions Through Analysis (CPSA) is to provide an in-depth review of innovative...

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Needham S, Premkumar N, Pols J, et al. Transforming drug discovery and development through innovation: past, present and future. Bioanalysis. 2013;5(3):275-9doi: 10.4155/bio.12.320.
Needham, S., Premkumar, N., Pols, J., & Lee, M. (2013). Transforming drug discovery and development through innovation: past, present and future. Bioanalysis, 5(3), 275-9. https://doi.org/10.4155/bio.12.320
Needham, Shane, et al. "Transforming drug discovery and development through innovation: past, present and future." Bioanalysis vol. 5,3 (2013): 275-9. doi: https://doi.org/10.4155/bio.12.320
Needham S, Premkumar N, Pols J, Lee M. Transforming drug discovery and development through innovation: past, present and future. Bioanalysis. 2013 Feb;5(3):275-9. doi: 10.4155/bio.12.320. PMID: 23394693.
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Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review.

Carbohydrate polymers

Neves RM, Ornaghi HL, Zattera AJ, Amico SC.
PMID: 33436199
Carbohydr Polym. 2021 Mar 01;255:117366. doi: 10.1016/j.carbpol.2020.117366. Epub 2020 Nov 09.

Cellulose and its derivatives are widely explored for films and thickening of pharmaceutical solutions, in paints, as reinforcement in composites, among others. This versatility is due to advantages such as renewability, low cost, and environmental friendliness. When used in...

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Neves RM, Ornaghi HL, Zattera AJ, et al. Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review. Carbohydr Polym. 2020;255:117366doi: 10.1016/j.carbpol.2020.117366.
Neves, R. M., Ornaghi, H. L., Zattera, A. J., & Amico, S. C. (2021). Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review. Carbohydrate polymers, 255117366. https://doi.org/10.1016/j.carbpol.2020.117366
Neves, Roberta Motta, et al. "Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review." Carbohydrate polymers vol. 255 (2021): 117366. doi: https://doi.org/10.1016/j.carbpol.2020.117366
Neves RM, Ornaghi HL, Zattera AJ, Amico SC. Recent studies on modified cellulose/nanocellulose epoxy composites: A systematic review. Carbohydr Polym. 2021 Mar 01;255:117366. doi: 10.1016/j.carbpol.2020.117366. Epub 2020 Nov 09. PMID: 33436199.
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Formulation Considerations for Autologous T Cell Drug Products.

Pharmaceutics

van der Walle CF, Godbert S, Saito G, Azhari Z.
PMID: 34452278
Pharmaceutics. 2021 Aug 23;13(8). doi: 10.3390/pharmaceutics13081317.

Genetically modified autologous T cells have become an established immunotherapy in the fight against cancer. The manufacture of chimeric antigen receptor (CAR) and αβ-T cell receptor (TCR) transduced T cells poses unique challenges, including the formulation, cryopreservation and fill-finish...

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van der Walle CF, Godbert S, Saito G, et al. Formulation Considerations for Autologous T Cell Drug Products. Pharmaceutics. 2021;13(8)doi: 10.3390/pharmaceutics13081317.
van der Walle, C. F., Godbert, S., Saito, G., & Azhari, Z. (2021). Formulation Considerations for Autologous T Cell Drug Products. Pharmaceutics, 13(8), . https://doi.org/10.3390/pharmaceutics13081317
van der Walle, Christopher F, et al. "Formulation Considerations for Autologous T Cell Drug Products." Pharmaceutics vol. 13,8 (2021). doi: https://doi.org/10.3390/pharmaceutics13081317
van der Walle CF, Godbert S, Saito G, Azhari Z. Formulation Considerations for Autologous T Cell Drug Products. Pharmaceutics. 2021 Aug 23;13(8). doi: 10.3390/pharmaceutics13081317. PMID: 34452278; PMCID: PMC8400304.
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Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus.

PeerJ

Ijaz MK, Nims RW, de Szalay S, Rubino JR.
PMID: 34616601
PeerJ. 2021 Sep 17;9:e12041. doi: 10.7717/peerj.12041. eCollection 2021.

Public Health Agencies worldwide (World Health Organization, United States Centers for Disease Prevention & Control, Chinese Center for Disease Control and Prevention, European Centre for Disease Prevention and Control, etc.) are recommending hand washing with soap and water for...

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Ijaz MK, Nims RW, de Szalay S, et al. Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus. PeerJ. 2021;9:e12041doi: 10.7717/peerj.12041.
Ijaz, M. K., Nims, R. W., de Szalay, S., & Rubino, J. R. (2021). Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus. PeerJ, 9e12041. https://doi.org/10.7717/peerj.12041
Ijaz, M Khalid, et al. "Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus." PeerJ vol. 9 (2021): e12041. doi: https://doi.org/10.7717/peerj.12041
Ijaz MK, Nims RW, de Szalay S, Rubino JR. Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus. PeerJ. 2021 Sep 17;9:e12041. doi: 10.7717/peerj.12041. eCollection 2021. PMID: 34616601; PMCID: PMC8451441.
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Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review.

Case reports in pediatrics

Sharma D, Patel A, Soni P, Sharma P, Gupta B.
PMID: 27648334
Case Rep Pediatr. 2016;2016:7609602. doi: 10.1155/2016/7609602. Epub 2016 Aug 25.

Empedobacter brevis is gram-negative bacilli that belongs to Flavobacteriaceae family. It was previously known with name of Flavobacterium breve. The reservoir of these bacteria is soil, plants, water, food, hospital water sources, including incubators, sinks, faucets, tap water, hemodialysis...

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Sharma D, Patel A, Soni P, et al. Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review. Case Rep Pediatr. 2016;2016:7609602doi: 10.1155/2016/7609602.
Sharma, D., Patel, A., Soni, P., Sharma, P., & Gupta, B. (2016). Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review. Case reports in pediatrics, 20167609602. https://doi.org/10.1155/2016/7609602
Sharma, Deepak, et al. "Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review." Case reports in pediatrics vol. 2016 (2016): 7609602. doi: https://doi.org/10.1155/2016/7609602
Sharma D, Patel A, Soni P, Sharma P, Gupta B. Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review. Case Rep Pediatr. 2016;2016:7609602. doi: 10.1155/2016/7609602. Epub 2016 Aug 25. PMID: 27648334; PMCID: PMC5014977.
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Inactivation of caliciviruses.

Pharmaceuticals (Basel, Switzerland)

Nims R, Plavsic M.
PMID: 24276023
Pharmaceuticals (Basel). 2013 Mar 21;6(3):358-92. doi: 10.3390/ph6030358.

The Caliciviridae family of viruses contains clinically important human and animal pathogens, as well as vesivirus 2117, a known contaminant of biopharmaceutical manufacturing processes employing Chinese hamster cells. An extensive literature exists for inactivation of various animal caliciviruses, especially...

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Nims R, Plavsic M. Inactivation of caliciviruses. Pharmaceuticals (Basel). 2013;6(3):358-92doi: 10.3390/ph6030358.
Nims, R., & Plavsic, M. (2013). Inactivation of caliciviruses. Pharmaceuticals (Basel, Switzerland), 6(3), 358-92. https://doi.org/10.3390/ph6030358
Nims, Raymond, and Plavsic, Mark. "Inactivation of caliciviruses." Pharmaceuticals (Basel, Switzerland) vol. 6,3 (2013): 358-92. doi: https://doi.org/10.3390/ph6030358
Nims R, Plavsic M. Inactivation of caliciviruses. Pharmaceuticals (Basel). 2013 Mar 21;6(3):358-92. doi: 10.3390/ph6030358. PMID: 24276023; PMCID: PMC3816691.
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Indirect transmission of severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2): What do we know and what do we not know?.

Infection control and hospital epidemiology

Ijaz MK, Nims RW, McKinney J.
PMID: 33557961
Infect Control Hosp Epidemiol. 2021 Feb 09;1-2. doi: 10.1017/ice.2021.57. Epub 2021 Feb 09.

No abstract available.

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Ijaz MK, Nims RW, McKinney J. Indirect transmission of severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2): What do we know and what do we not know?. Infect Control Hosp Epidemiol. 2021;1-2doi: 10.1017/ice.2021.57.
Ijaz, M. K., Nims, R. W., & McKinney, J. (2021). Indirect transmission of severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2): What do we know and what do we not know?. Infection control and hospital epidemiology, 1-2. https://doi.org/10.1017/ice.2021.57
Ijaz, M Khalid, et al. "Indirect transmission of severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2): What do we know and what do we not know?." Infection control and hospital epidemiology vol. (2021): 1-2. doi: https://doi.org/10.1017/ice.2021.57
Ijaz MK, Nims RW, McKinney J. Indirect transmission of severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2): What do we know and what do we not know?. Infect Control Hosp Epidemiol. 2021 Feb 09;1-2. doi: 10.1017/ice.2021.57. Epub 2021 Feb 09. PMID: 33557961; PMCID: PMC7943946.
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Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus.

Infection prevention in practice

Cutts TA, Nims RW, Theriault SS, Bruning E, Rubino JR, Ijaz MK.
PMID: 34368739
Infect Prev Pract. 2021 Jan 20;3(1):100122. doi: 10.1016/j.infpip.2021.100122. eCollection 2021 Mar.

BACKGROUND: Hand washing is an important targeted hygiene intervention for limiting the spread of infectious agents, including the Ebola virus, which continues to re-emerge. We have assessed the virucidal efficacy of a commercially available liquid hand wash product (LHW)...

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Cutts TA, Nims RW, Theriault SS, et al. Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus. Infect Prev Pract. 2021;3(1):100122doi: 10.1016/j.infpip.2021.100122.
Cutts, T. A., Nims, R. W., Theriault, S. S., Bruning, E., Rubino, J. R., & Ijaz, M. K. (2021). Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus. Infection prevention in practice, 3(1), 100122. https://doi.org/10.1016/j.infpip.2021.100122
Cutts, T A, et al. "Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus." Infection prevention in practice vol. 3,1 (2021): 100122. doi: https://doi.org/10.1016/j.infpip.2021.100122
Cutts TA, Nims RW, Theriault SS, Bruning E, Rubino JR, Ijaz MK. Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus. Infect Prev Pract. 2021 Jan 20;3(1):100122. doi: 10.1016/j.infpip.2021.100122. eCollection 2021 Mar. PMID: 34368739; PMCID: PMC8336303.
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Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol.

Pharmaceutics

Rigaud S, Mathiron D, Moufawad T, Landy D, Djedaini-Pilard F, Marçon F.
PMID: 34834163
Pharmaceutics. 2021 Oct 20;13(11). doi: 10.3390/pharmaceutics13111746.

We studied the effect of several CDs on carvedilol's solubility and chemical stability in various aqueous media. Our present results show that it is possible to achieve a carvedilol concentration of 5 mg/mL (12.3 mM) in the presence of...

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Rigaud S, Mathiron D, Moufawad T, et al. Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol. Pharmaceutics. 2021;13(11)doi: 10.3390/pharmaceutics13111746.
Rigaud, S., Mathiron, D., Moufawad, T., Landy, D., Djedaini-Pilard, F., & Marçon, F. (2021). Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol. Pharmaceutics, 13(11), . https://doi.org/10.3390/pharmaceutics13111746
Rigaud, Sébastien, et al. "Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol." Pharmaceutics vol. 13,11 (2021). doi: https://doi.org/10.3390/pharmaceutics13111746
Rigaud S, Mathiron D, Moufawad T, Landy D, Djedaini-Pilard F, Marçon F. Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol. Pharmaceutics. 2021 Oct 20;13(11). doi: 10.3390/pharmaceutics13111746. PMID: 34834163; PMCID: PMC8620534.
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Green Solvents Combined with Bioactive Compounds as Delivery Systems: Present Status and Future Trends.

ACS applied bio materials

Silva SS, Gomes JM, Reis RL, Kundu SC.
PMID: 35006819
ACS Appl Bio Mater. 2021 May 17;4(5):4000-4013. doi: 10.1021/acsabm.1c00013. Epub 2021 Apr 13.

Green solvents such as ionic liquids (ILs) unlock possibilities for developing innovative biomedical and pharmaceutical solutions. ILs are the most investigated solvents for compound extractions, as reaction media and/or catalysts, and a desired eco-friendly solvent to process biomacromolecules for...

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Silva SS, Gomes JM, Reis RL, et al. Green Solvents Combined with Bioactive Compounds as Delivery Systems: Present Status and Future Trends. ACS Appl Bio Mater. 2021;4(5):4000-4013doi: 10.1021/acsabm.1c00013.
Silva, S. S., Gomes, J. M., Reis, R. L., & Kundu, S. C. (2021). Green Solvents Combined with Bioactive Compounds as Delivery Systems: Present Status and Future Trends. ACS applied bio materials, 4(5), 4000-4013. https://doi.org/10.1021/acsabm.1c00013
Silva, Simone S, et al. "Green Solvents Combined with Bioactive Compounds as Delivery Systems: Present Status and Future Trends." ACS applied bio materials vol. 4,5 (2021): 4000-4013. doi: https://doi.org/10.1021/acsabm.1c00013
Silva SS, Gomes JM, Reis RL, Kundu SC. Green Solvents Combined with Bioactive Compounds as Delivery Systems: Present Status and Future Trends. ACS Appl Bio Mater. 2021 May 17;4(5):4000-4013. doi: 10.1021/acsabm.1c00013. Epub 2021 Apr 13. PMID: 35006819.
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Theranostics Health: personalized therapy and diagnosis today.

Personalized medicine

Roland D.
PMID: 29793281
Per Med. 2007 Nov;4(4):439-444. doi: 10.2217/17410541.4.4.439.

Theranostics Health is a young company using mature proprietary technology to make personalized medicine possible today. The firm provides pharmaceutical scientists, clinical trial clinicians and treating physicians with highly detailed portraits of protein drug target pathways and critical patient...

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Roland D. Theranostics Health: personalized therapy and diagnosis today. Per Med. 2007;4(4):439-444doi: 10.2217/17410541.4.4.439.
Roland, D. (2007). Theranostics Health: personalized therapy and diagnosis today. Personalized medicine, 4(4), 439-444. https://doi.org/10.2217/17410541.4.4.439
Roland, David. "Theranostics Health: personalized therapy and diagnosis today." Personalized medicine vol. 4,4 (2007): 439-444. doi: https://doi.org/10.2217/17410541.4.4.439
Roland D. Theranostics Health: personalized therapy and diagnosis today. Per Med. 2007 Nov;4(4):439-444. doi: 10.2217/17410541.4.4.439. PMID: 29793281.
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Stability of Hydrocortisone Preservative-Free Oral Solutions.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Chappe J, Osman N, Cisternino S, Fontan JE, Schlatter J.
PMID: 26170771
J Pediatr Pharmacol Ther. 2015 May-Jun;20(3):197-202. doi: 10.5863/1551-6776-20.3.197.

OBJECTIVES: The physical and chemical stability of a preservative-free oral solution of hydrocortisone succinate was studied at different pH values and storage temperatures.METHODS: Oral solutions of hydrocortisone 1 mg/mL were prepared by dissolving hydrocortisone succinate powder in citrate buffers...

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Chappe J, Osman N, Cisternino S, et al. Stability of Hydrocortisone Preservative-Free Oral Solutions. J Pediatr Pharmacol Ther. 2015;20(3):197-202doi: 10.5863/1551-6776-20.3.197.
Chappe, J., Osman, N., Cisternino, S., Fontan, J. E., & Schlatter, J. (2015). Stability of Hydrocortisone Preservative-Free Oral Solutions. The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 20(3), 197-202. https://doi.org/10.5863/1551-6776-20.3.197
Chappe, Julie, et al. "Stability of Hydrocortisone Preservative-Free Oral Solutions." The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG vol. 20,3 (2015): 197-202. doi: https://doi.org/10.5863/1551-6776-20.3.197
Chappe J, Osman N, Cisternino S, Fontan JE, Schlatter J. Stability of Hydrocortisone Preservative-Free Oral Solutions. J Pediatr Pharmacol Ther. 2015 May-Jun;20(3):197-202. doi: 10.5863/1551-6776-20.3.197. PMID: 26170771; PMCID: PMC4471713.
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Showing 1 to 12 of 21 entries