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Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism.

Nutrition & metabolism

Hakimi P, Johnson MT, Yang J, Lepage DF, Conlon RA, Kalhan SC, Reshef L, Tilghman SM, Hanson RW.
PMID: 16300682
Nutr Metab (Lond). 2005 Nov 21;2:33. doi: 10.1186/1743-7075-2-33.

BACKGROUND: The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function.METHODS: The gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32)...

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