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The presence of 17α,20β-dihydroxy-4-pregnen-3-one receptor activity in the ovary of the brook trout,Salvelinus fontinalis, during terminal stages of oocyte maturation.

Fish physiology and biochemistry

Maneckjee A, Weisbart M, Idler DR.
PMID: 24226897
Fish Physiol Biochem. 1989 Jan;6(1):19-38. doi: 10.1007/BF01875601.

The presence of 17α,20β-dihydroxy-4-pregnen-3-one (17α,20β-DHP) oocyte receptor activity has been demonstrated in brook troutSalvelinus fontinalis. Scatchard analyses of the cytosol fraction during various terminal stages of oocyte maturation gave a high equilibrium association constant (Ka) value of 1.394±0.669 10(8)M(-1)...

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Maneckjee A, Weisbart M, Idler DR. The presence of 17α,20β-dihydroxy-4-pregnen-3-one receptor activity in the ovary of the brook trout,Salvelinus fontinalis, during terminal stages of oocyte maturation. Fish Physiol Biochem. 1989;6(1):19-38doi: 10.1007/BF01875601.
Maneckjee, A., Weisbart, M., & Idler, D. R. (1989). The presence of 17α,20β-dihydroxy-4-pregnen-3-one receptor activity in the ovary of the brook trout,Salvelinus fontinalis, during terminal stages of oocyte maturation. Fish physiology and biochemistry, 6(1), 19-38. https://doi.org/10.1007/BF01875601
Maneckjee, A, et al. "The presence of 17α,20β-dihydroxy-4-pregnen-3-one receptor activity in the ovary of the brook trout,Salvelinus fontinalis, during terminal stages of oocyte maturation." Fish physiology and biochemistry vol. 6,1 (1989): 19-38. doi: https://doi.org/10.1007/BF01875601
Maneckjee A, Weisbart M, Idler DR. The presence of 17α,20β-dihydroxy-4-pregnen-3-one receptor activity in the ovary of the brook trout,Salvelinus fontinalis, during terminal stages of oocyte maturation. Fish Physiol Biochem. 1989 Jan;6(1):19-38. doi: 10.1007/BF01875601. PMID: 24226897.
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The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice.

American journal of obstetrics and gynecology

Shynlova O, Nadeem L, Dorogin A, Mesiano S, Lye SJ.
PMID: 34418351
Am J Obstet Gynecol. 2021 Aug 19; doi: 10.1016/j.ajog.2021.08.013. Epub 2021 Aug 19.

BACKGROUND: Progesterone, acting via its nuclear receptors called progesterone receptors, promotes myometrial relaxation during pregnancy, and suspension of this activity triggers labor. We previously found that 20α-hydroxysteroid dehydrogenase causes a local withdrawal of progesterone in the term and preterm...

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Shynlova O, Nadeem L, Dorogin A, et al. The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice. Am J Obstet Gynecol. 2021;doi: 10.1016/j.ajog.2021.08.013.
Shynlova, O., Nadeem, L., Dorogin, A., Mesiano, S., & Lye, S. J. (2021). The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice. American journal of obstetrics and gynecology, . https://doi.org/10.1016/j.ajog.2021.08.013
Shynlova, Oksana, et al. "The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice." American journal of obstetrics and gynecology vol. (2021). doi: https://doi.org/10.1016/j.ajog.2021.08.013
Shynlova O, Nadeem L, Dorogin A, Mesiano S, Lye SJ. The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice. Am J Obstet Gynecol. 2021 Aug 19; doi: 10.1016/j.ajog.2021.08.013. Epub 2021 Aug 19. PMID: 34418351.
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Classification and pharmacology of progestins.

Maturitas

Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH.
PMID: 19434889
Maturitas. 2008 Sep-Oct;61(1):171-80. doi: 10.1016/j.maturitas.2008.11.013.

Besides the natural progestin, progesterone, there are different classes of progestins, such as retroprogesterone (i.e. dydrogesterone), progesterone derivatives (i.e. medrogestone) 17alpha-hydroxyprogesterone derivatives (i.e. chlormadinone acetate, cyproterone acetate, medroxyprogesterone acetate, megestrol acetate), 19-norprogesterone derivatives (i.e. nomegestrol, promegestone, trimegestone, nesterone), 19-nortestosterone...

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Schindler AE, Campagnoli C, Druckmann R, et al. Classification and pharmacology of progestins. Maturitas. 2008;61(1):171-80doi: 10.1016/j.maturitas.2008.11.013.
Schindler, A. E., Campagnoli, C., Druckmann, R., Huber, J., Pasqualini, J. R., Schweppe, K. W., & Thijssen, J. H. (2008). Classification and pharmacology of progestins. Maturitas, 61(1), 171-80. https://doi.org/10.1016/j.maturitas.2008.11.013
Schindler, Adolf E, et al. "Classification and pharmacology of progestins." Maturitas vol. 61,1 (2008): 171-80. doi: https://doi.org/10.1016/j.maturitas.2008.11.013
Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1):171-80. doi: 10.1016/j.maturitas.2008.11.013. PMID: 19434889.
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