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Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.

World journal of hepatology

Reiter FP, Wimmer R, Wottke L, Artmann R, Nagel JM, Carranza MO, Mayr D, Rust C, Fickert P, Trauner M, Gerbes AL, Hohenester S, Denk GU.
PMID: 27004088
World J Hepatol. 2016 Mar 18;8(8):401-10. doi: 10.4254/wjh.v8.i8.401.

AIM: To study the interleukin-1 (IL-1) pathway as a therapeutic target for liver fibrosis in vitro and in vivo using the ATP-binding cassette transporter b4(-/-) (Abcb4(-/-)) mouse model.METHODS: Female and male Abcb4(-/-) mice from 6 to 13 mo of...

Complete Genome Sequence of Carbapenemase-Producing Klebsiella pneumoniae Myophage Matisse.

Genome announcements

Provasek VE, Lessor LE, Cahill JL, Rasche ES, Kuty Everett GF.
PMID: 26430049
Genome Announc. 2015 Oct 01;3(5). doi: 10.1128/genomeA.01136-15.

Klebsiella pneumoniae is a leading cause of nosocomial infections in the United States. Due to the emergence of multidrug-resistant strains, phages targeting K. pneumoniae may be a useful alternative against this pathogen. Here, we announce the complete genome of...

Polyphasic characterization of benthic cyanobacterial diversity from biofilms of the Guadarrama river (Spain): morphological, molecular, and ecological approaches(1).

Journal of phycology

Loza V, Berrendero E, Perona E, Mateo P.
PMID: 27008516
J Phycol. 2013 Apr;49(2):282-97. doi: 10.1111/jpy.12036. Epub 2013 Jan 24.

The occurrence and environmental factors responsible for the distribution of benthic cyanobacteria in running waters remain largely unexplored in comparison with those of other aquatic ecosystems. In this study, combined data of ecological characteristics, molecular analysis (based on 16S...

On the Angular Dependence of the Vicinal Fluorine-Fluorine Coupling Constant in 1,2-Difluoroethane:  Deviation from a Karplus-like Shape.

Journal of chemical theory and computation

Provasi PF, Sauer SP.
PMID: 26633061
J Chem Theory Comput. 2006 Jul;2(4):1019-27. doi: 10.1021/ct6000973.

The angular dependence of the vicinal fluorine-fluorine coupling constant, (3)JFF, for 1,2-difluoroethane has been investigated with several polarization propagator methods. (3)JFF and its four Ramsey contributions were calculated using the random phase approximation (RPA), its multiconfigurational generalization, and both...

Photophysics of α-furil at room temperature and 77 K: Spectroscopic and quantum chemical studies.

The Journal of chemical physics

Kundu P, Chattopadhyay N.
PMID: 27334172
J Chem Phys. 2016 Jun 21;144(23):234317. doi: 10.1063/1.4954155.

Steady state and time resolved spectroscopic measurements have been exploited to assign the emissions from different conformations of α-furil (2, 2'-furil) in solution phase at room temperature as well as cryogen (liquid nitrogen, LN2) frozen matrices of ethanol and...

Comparison the effect of three commercial enzymes for enzymatic hydrolysis of two substrates (rice bran protein concentrate and soy-been protein) with SDS-PAGE.

Journal of food science and technology

Ahmadifard N, Murueta JH, Abedian-Kenari A, Motamedzadegan A, Jamali H.
PMID: 27162408
J Food Sci Technol. 2016 Feb;53(2):1279-84. doi: 10.1007/s13197-015-2087-6. Epub 2015 Nov 09.

In this research enzymatic hydrolysis of rice bran protein concentrate (RBPC) and soybean Protein (SBP) as control were studied with 3 commercial enzymes (Alcalase®, Papain and acommercial 3-enzyme cocktail containing of 1.6 mg ml(-1) Trypsin, 3.1 mg ml(-1) Chymotrypsin,...

A case report of paraproteinemia-associated pauci-immune glomerulonephritis - a new form of monoclonal gammopathy of renal significance?.

Clinical nephrology. Case studies

Rope R, Kambham N, Arora N.
PMID: 29043147
Clin Nephrol Case Stud. 2017 Aug 17;5:48-53. doi: 10.5414/CNCS109160. eCollection 2017.

BACKGROUND: Renal disease associated with paraproteinemias is classically predicated upon pathologic paraprotein deposition in the kidney. However, growing evidence suggests that paraproteins may be able to systemically activate complement or neutrophils to drive renal damage. This may provide an...

Partial Characterization of α-Galactosidic Activity from the Antarctic Bacterial Isolate, Paenibacillus sp. LX-20 as a Potential Feed Enzyme Source.

Asian-Australasian journal of animal sciences

Park I, Lee J, Cho J.
PMID: 25049637
Asian-Australas J Anim Sci. 2012 Jun;25(6):852-60. doi: 10.5713/ajas.2011.11501.

An Antarctic bacterial isolate displaying extracellular α-galactosidic activity was named Paenibacillus sp. LX-20 based on 16S rRNA gene sequence analysis. Optimal activity for the LX-20 α-galactosidase occurred at pH 6.0-6.5 and 45°C. The enzyme immobilized on the smart polymer...

Purification and quantitative changes of mitochondrial DNA in etiolated cucumber seedlings.

Planta

Vedel F.
PMID: 24435341
Planta. 1975 Jan;125(2):171-80. doi: 10.1007/BF00388703.

The mtDNA (mitochondrial DNA) extracted from etiolated seedlings of Cucumis sativus L. has been purified by a three-step procedure: RNase and pronase treatment, bio-gel filtration, analytical CsCl gradient centrifugation. This procedure appeared rapid, suitable for small quantities of DNA...

Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.

ACS medicinal chemistry letters

Bogen SL, Pan W, Gibeau CR, Lahue BR, Ma Y, Nair LG, Seigel E, Shipps GW, Tian Y, Wang Y, Lin Y, Liu M, Liu S, Mirza A, Wang X, Lipari P, Seidel-Dugan C, Hicklin DJ, Bishop WR, Rindgen D, Nomeir A, Prosise W, Reichert P, Scapin G, Strickland C, Doll RJ.
PMID: 26985323
ACS Med Chem Lett. 2016 Jan 20;7(3):324-9. doi: 10.1021/acsmedchemlett.5b00472. eCollection 2016 Mar 10.

A new subseries of substituted piperidines as p53-HDM2 inhibitors exemplified by 21 has been developed from the initial lead 1. Research focused on optimization of a crucial HDM2 Trp23-ligand interaction led to the identification of 2-(trifluoromethyl)thiophene as the preferred...

Biological and molecular characterization of classical swine fever challenge virus from India.

Veterinary world

Kumar P, Upmanyu V, Dhar P.
PMID: 27047093
Vet World. 2015 Mar;8(3):330-5. doi: 10.14202/vetworld.2015.330-335. Epub 2015 Mar 16.

AIM: The aim of this study was biological and molecular characterization of classical swine fever (CSF) challenge virus from India.MATERIALS AND METHODS: CSF challenge virus maintained at Division of Biological standardization was experimentally infected to two seronegative piglets. The...

Correction to "New Insights into Peptide-Silver Nanoparticle Interaction: Deciphering the Role of Cysteine and Lysine in the Peptide Sequence".

Langmuir : the ACS journal of surfaces and colloids

Poblete H, Agarwal A, Thomas SS, Bohne C, Ravichandran R, Phopase J, Comer J, Alarcon EI.
PMID: 28558219
Langmuir. 2017 Jun 13;33(23):5973. doi: 10.1021/acs.langmuir.7b01545. Epub 2017 May 30.

No abstract available.

Showing 1 to 12 of 541 entries