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Showing 1 to 3 of 3 entries
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siRNA-Mediated Suppression of Synuclein γ Inhibits MDA-MB-231 Cell Migration and Proliferation by Downregulating the Phosphorylation of AKT and ERK.

Journal of breast cancer

He J, Xie N, Yang J, Guan H, Chen W, Wu H, Yuan Z, Wang K, Li G, Sun J, Yu L.
PMID: 25320617
J Breast Cancer. 2014 Sep;17(3):200-6. doi: 10.4048/jbc.2014.17.3.200. Epub 2014 Sep 30.

PURPOSE: Synuclein-γ (SNCG), which was initially identified as breast cancer specific gene 1, is highly expressed in advanced breast cancers, but not in normal or benign breast tissue. This study aimed to evaluate the effects of SNCG siRNA-treatment on...

Role of heat-shock proteins in infection of human adenocarcinoma cell line MCF-7 by tumor-adapted rotavirus isolates.

Colombia medica (Cali, Colombia)

Perez C, Rico J, Guerrero C, Acosta O.
PMID: 33911319
Colomb Med (Cali). 2021 Mar 16;52(1):e2024196. doi: 10.25100/cm.v51i4.4196.

BACKGROUND: Viruses are being used as alternative and complementary tools for treating cancers. Oncolytic viruses exhibit tumor tropism, ability to enhance anti-tumor immunity and ability to be used in combination with conventional chemotherapy and radiotherapy. We have recently selected...

Mechanism of total glucosides from Chishao (Radix Paeoniae Rubra) on proliferation and apoptosis of hepatocellular carcinoma cells via phosphatase and tensin homolog deleted on chromosome ten / phosphatidylinositol 3-kinase / protein kinase B signaling pathway.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Fan BB, Li TJ, Meng XS, Wang S, Bao YR, Wang F.
PMID: 34708625
J Tradit Chin Med. 2021 Oct;41(5):677-683. doi: 10.19852/j.cnki.jtcm.2021.05.003.

OBJECTIVE: To investigate the possible molecular mechanism of total glycosides of Chishao (Radix Paeoniae Rubra) (TG-RPR) on proliferation and apoptosis of hepatocellular carcinoma cells.METHODS: The proliferation of TG-RPR on HepG2 cells was detected using the 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay....

Showing 1 to 3 of 3 entries