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A Review of Driver Genetic Alterations in Thyroid Cancers.

Iranian journal of pathology

Khatami F, Tavangar SM.
PMID: 30697281
Iran J Pathol. 2018;13(2):125-135. Epub 2018 Jul 17.

Thyroid cancer is a frequent endocrine-related malignancy with continuously increasing incidence, and recently the development in understanding its molecular pathogenesis is mainly through the explanation of the original role of several key signaling pathways and related molecular distributors. Central...

Evaluation and diagnostic value of next-generation sequencing analysis of residual liquid-based cytology specimens of pancreatic masses.

Cancer cytopathology

Sekita-Hatakeyama Y, Fujii T, Nishikawa T, Mitoro A, Sawai M, Itami H, Morita K, Uchiyama T, Takeda M, Sho M, Yoshiji H, Hatakeyama K, Ohbayashi C.
PMID: 34665935
Cancer Cytopathol. 2021 Oct 19; doi: 10.1002/cncy.22525. Epub 2021 Oct 19.

BACKGROUND: Liquid-based cytology (LBC) is a widely used method for processing specimens obtained by endoscopic biopsy. This study evaluated next-generation sequencing (NGS) analysis of LBC specimens to improve the diagnostic accuracy of pancreatic lesions.METHODS: Upon the diagnosis of a...

The current understanding of KRAS protein structure and dynamics.

Computational and structural biotechnology journal

Pantsar T.
PMID: 31988705
Comput Struct Biotechnol J. 2019 Dec 26;18:189-198. doi: 10.1016/j.csbj.2019.12.004. eCollection 2020.

One of the most common drivers in human cancer is the mutant KRAS protein. Not so long ago KRAS was considered as an undruggable oncoprotein. After a long struggle, however, we finally see some light at the end of...

Showing 1 to 3 of 3 entries