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Showing 1 to 12 of 208 entries
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Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events.

Nature immunology

Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, Hayday AC.
PMID: 27002849
Nat Immunol. 2016 Apr;17(4):469. doi: 10.1038/ni0416-469b.

No abstract available.

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Sobolev O, Binda E, O'Farrell S, et al. Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nat Immunol. 2016;17(4):469doi: 10.1038/ni0416-469b.
Sobolev, O., Binda, E., O'Farrell, S., Lorenc, A., Pradines, J., Huang, Y., Duffner, J., Schulz, R., Cason, J., Zambon, M., Malim, M. H., Peakman, M., Cope, A., Capila, I., Kaundinya, G. V., & Hayday, A. C. (2016). Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nature immunology, 17(4), 469. https://doi.org/10.1038/ni0416-469b
Sobolev, Olga, et al. "Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events." Nature immunology vol. 17,4 (2016): 469. doi: https://doi.org/10.1038/ni0416-469b
Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, Hayday AC. Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nat Immunol. 2016 Apr;17(4):469. doi: 10.1038/ni0416-469b. PMID: 27002849.
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Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors.

ACS medicinal chemistry letters

Barsanti PA, Aversa RJ, Jin X, Pan Y, Lu Y, Elling R, Jain R, Knapp M, Lan J, Lin X, Rudewicz P, Sim J, Taricani L, Thomas G, Xiao L, Yue Q.
PMID: 25589927
ACS Med Chem Lett. 2014 Nov 20;6(1):37-41. doi: 10.1021/ml500353p. eCollection 2015 Jan 08.

A saturation strategy focused on improving the selectivity and physicochemical properties of ATR inhibitor HTS hit 1 led to a novel series of highly potent and selective tetrahydropyrazolo[1,5-a]pyrazines. Use of PI3Kα mutants as ATR crystal structure surrogates was instrumental...

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Barsanti PA, Aversa RJ, Jin X, et al. Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors. ACS Med Chem Lett. 2014;6(1):37-41doi: 10.1021/ml500353p.
Barsanti, P. A., Aversa, R. J., Jin, X., Pan, Y., Lu, Y., Elling, R., Jain, R., Knapp, M., Lan, J., Lin, X., Rudewicz, P., Sim, J., Taricani, L., Thomas, G., Xiao, L., & Yue, Q. (2015). Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors. ACS medicinal chemistry letters, 6(1), 37-41. https://doi.org/10.1021/ml500353p
Barsanti, Paul A, et al. "Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors." ACS medicinal chemistry letters vol. 6,1 (2015): 37-41. doi: https://doi.org/10.1021/ml500353p
Barsanti PA, Aversa RJ, Jin X, Pan Y, Lu Y, Elling R, Jain R, Knapp M, Lan J, Lin X, Rudewicz P, Sim J, Taricani L, Thomas G, Xiao L, Yue Q. Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors. ACS Med Chem Lett. 2014 Nov 20;6(1):37-41. doi: 10.1021/ml500353p. eCollection 2015 Jan 08. PMID: 25589927; PMCID: PMC4291715.
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Spin Crossover in Fe(II)-M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines.

Inorganic chemistry

Kucheriv OI, Shylin SI, Ksenofontov V, Dechert S, Haukka M, Fritsky IO, Gural'skiy IA.
PMID: 27120049
Inorg Chem. 2016 May 16;55(10):4906-14. doi: 10.1021/acs.inorgchem.6b00446. Epub 2016 Apr 27.

Discovery of spin-crossover (SCO) behavior in the family of Fe(II)-based Hofmann clathrates has led to a "new rush" in the field of bistable molecular materials. To date this class of SCO complexes is represented by several dozens of individual...

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Kucheriv OI, Shylin SI, Ksenofontov V, et al. Spin Crossover in Fe(II)-M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines. Inorg Chem. 2016;55(10):4906-14doi: 10.1021/acs.inorgchem.6b00446.
Kucheriv, O. I., Shylin, S. I., Ksenofontov, V., Dechert, S., Haukka, M., Fritsky, I. O., & Gural'skiy, I. A. (2016). Spin Crossover in Fe(II)-M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines. Inorganic chemistry, 55(10), 4906-14. https://doi.org/10.1021/acs.inorgchem.6b00446
Kucheriv, Olesia I, et al. "Spin Crossover in Fe(II)-M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines." Inorganic chemistry vol. 55,10 (2016): 4906-14. doi: https://doi.org/10.1021/acs.inorgchem.6b00446
Kucheriv OI, Shylin SI, Ksenofontov V, Dechert S, Haukka M, Fritsky IO, Gural'skiy IA. Spin Crossover in Fe(II)-M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines. Inorg Chem. 2016 May 16;55(10):4906-14. doi: 10.1021/acs.inorgchem.6b00446. Epub 2016 Apr 27. PMID: 27120049.
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Novel pyrazines from the head of Australian ponerine antRhytidoponera metallica.

Journal of chemical ecology

Tecle B, Sun CM, Brophy JJ, Toia RF.
PMID: 24302390
J Chem Ecol. 1987 Aug;13(8):1811-22. doi: 10.1007/BF01013230.

The novel pyrazines, (E)- and (Z)-5-methyl-3-(2-methylbutyl)-2-(3-methylbut-1-enyl)pyrazine, (E)- and (Z)-5-methyl-3-isopentyl-2-(3-methylbut-1-enyl) pyrazine, (E)- and (Z)-5-methyl-3-(2-methylbutyl)-2-(3-methylpent-1-enyl)pyrazine, (E)- and (Z)-5-methyl-3-isopentyl-2-(3-methylpentl-enyl) pyrazine, together with the known pyrazines, 2,5-dimethyl-3-(2-methylbutyl)pyrazine and 2,5-dimethyl-3-isopentylpyrazine, have been identified from the head of the Australian ponerine antRhytidoponera metallica. Alkanes and...

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Tecle B, Sun CM, Brophy JJ, et al. Novel pyrazines from the head of Australian ponerine antRhytidoponera metallica. J Chem Ecol. 1987;13(8):1811-22doi: 10.1007/BF01013230.
Tecle, B., Sun, C. M., Brophy, J. J., & Toia, R. F. (1987). Novel pyrazines from the head of Australian ponerine antRhytidoponera metallica. Journal of chemical ecology, 13(8), 1811-22. https://doi.org/10.1007/BF01013230
Tecle, B, et al. "Novel pyrazines from the head of Australian ponerine antRhytidoponera metallica." Journal of chemical ecology vol. 13,8 (1987): 1811-22. doi: https://doi.org/10.1007/BF01013230
Tecle B, Sun CM, Brophy JJ, Toia RF. Novel pyrazines from the head of Australian ponerine antRhytidoponera metallica. J Chem Ecol. 1987 Aug;13(8):1811-22. doi: 10.1007/BF01013230. PMID: 24302390.
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Transition-metal-catalyzed asymmetric allylic dearomatization reactions.

Accounts of chemical research

Zhuo CX, Zheng C, You SL.
PMID: 24940612
Acc Chem Res. 2014 Aug 19;47(8):2558-73. doi: 10.1021/ar500167f. Epub 2014 Jun 18.

Dearomatization reactions serve as powerful methods for the synthesis of highly functionalized, three-dimensional structures starting with simple planar aromatic compounds. Among processes of this type, catalytic asymmetric dearomatization (CADA) reactions are attractive owing to the large number of aromatic...

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Zhuo CX, Zheng C, You SL. Transition-metal-catalyzed asymmetric allylic dearomatization reactions. Acc Chem Res. 2014;47(8):2558-73doi: 10.1021/ar500167f.
Zhuo, C. X., Zheng, C., & You, S. L. (2014). Transition-metal-catalyzed asymmetric allylic dearomatization reactions. Accounts of chemical research, 47(8), 2558-73. https://doi.org/10.1021/ar500167f
Zhuo, Chun-Xiang, et al. "Transition-metal-catalyzed asymmetric allylic dearomatization reactions." Accounts of chemical research vol. 47,8 (2014): 2558-73. doi: https://doi.org/10.1021/ar500167f
Zhuo CX, Zheng C, You SL. Transition-metal-catalyzed asymmetric allylic dearomatization reactions. Acc Chem Res. 2014 Aug 19;47(8):2558-73. doi: 10.1021/ar500167f. Epub 2014 Jun 18. PMID: 24940612.
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Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine.

Science advances

Wu K, Huang Z, Qi X, Li Y, Zhang G, Liu C, Yi H, Meng L, Bunel EE, Miller JT, Pao CW, Lee JF, Lan Y, Lei A.
PMID: 26601302
Sci Adv. 2015 Oct 09;1(9):e1500656. doi: 10.1126/sciadv.1500656. eCollection 2015 Oct.

Copper-catalyzed aerobic oxidative C-H/N-H coupling between simple ketones and diamines was developed toward the synthesis of a variety of pyrazines. Various substituted ketones were compatible for this transformation. Preliminary mechanistic investigations indicated that radical species were involved. X-ray absorption...

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Wu K, Huang Z, Qi X, et al. Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine. Sci Adv. 2015;1(9):e1500656doi: 10.1126/sciadv.1500656.
Wu, K., Huang, Z., Qi, X., Li, Y., Zhang, G., Liu, C., Yi, H., Meng, L., Bunel, E. E., Miller, J. T., Pao, C. W., Lee, J. F., Lan, Y., & Lei, A. (2015). Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine. Science advances, 1(9), e1500656. https://doi.org/10.1126/sciadv.1500656
Wu, Kun, et al. "Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine." Science advances vol. 1,9 (2015): e1500656. doi: https://doi.org/10.1126/sciadv.1500656
Wu K, Huang Z, Qi X, Li Y, Zhang G, Liu C, Yi H, Meng L, Bunel EE, Miller JT, Pao CW, Lee JF, Lan Y, Lei A. Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine. Sci Adv. 2015 Oct 09;1(9):e1500656. doi: 10.1126/sciadv.1500656. eCollection 2015 Oct. PMID: 26601302; PMCID: PMC4646816.
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Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis.

ACS medicinal chemistry letters

Liu J, Guiadeen D, Krikorian A, Gao X, Wang J, Boga SB, Alhassan AB, Yu Y, Vaccaro H, Liu S, Yang C, Wu H, Cooper A, de Man J, Kaptein A, Maloney K, Hornak V, Gao YD, Fischmann TO, Raaijmakers H, Vu-Pham D, Presland J, Mansueto M, Xu Z, Leccese E, Zhang-Hoover J, Knemeyer I, Garlisi CG, Bays N, Stivers P, Brandish PE, Hicks A, Kim R, Kozlowski JA.
PMID: 26985298
ACS Med Chem Lett. 2015 Dec 19;7(2):198-203. doi: 10.1021/acsmedchemlett.5b00463. eCollection 2016 Feb 11.

Bruton's tyrosine kinase (BTK) is a Tec family kinase with a well-defined role in the B cell receptor (BCR) pathway. It has become an attractive kinase target for selective B cell inhibition and for the treatment of B cell...

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Liu J, Guiadeen D, Krikorian A, et al. Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis. ACS Med Chem Lett. 2015;7(2):198-203doi: 10.1021/acsmedchemlett.5b00463.
Liu, J., Guiadeen, D., Krikorian, A., Gao, X., Wang, J., Boga, S. B., Alhassan, A. B., Yu, Y., Vaccaro, H., Liu, S., Yang, C., Wu, H., Cooper, A., de Man, J., Kaptein, A., Maloney, K., Hornak, V., Gao, Y. D., Fischmann, T. O., Raaijmakers, H., Vu-Pham, D., Presland, J., Mansueto, M., Xu, Z., Leccese, E., Zhang-Hoover, J., Knemeyer, I., Garlisi, C. G., Bays, N., Stivers, P., Brandish, P. E., Hicks, A., Kim, R., & Kozlowski, J. A. (2016). Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis. ACS medicinal chemistry letters, 7(2), 198-203. https://doi.org/10.1021/acsmedchemlett.5b00463
Liu, Jian, et al. "Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis." ACS medicinal chemistry letters vol. 7,2 (2016): 198-203. doi: https://doi.org/10.1021/acsmedchemlett.5b00463
Liu J, Guiadeen D, Krikorian A, Gao X, Wang J, Boga SB, Alhassan AB, Yu Y, Vaccaro H, Liu S, Yang C, Wu H, Cooper A, de Man J, Kaptein A, Maloney K, Hornak V, Gao YD, Fischmann TO, Raaijmakers H, Vu-Pham D, Presland J, Mansueto M, Xu Z, Leccese E, Zhang-Hoover J, Knemeyer I, Garlisi CG, Bays N, Stivers P, Brandish PE, Hicks A, Kim R, Kozlowski JA. Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis. ACS Med Chem Lett. 2015 Dec 19;7(2):198-203. doi: 10.1021/acsmedchemlett.5b00463. eCollection 2016 Feb 11. PMID: 26985298; PMCID: PMC4753550.
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Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems.

ChemistryOpen

Verolet Q, Soleimanpour S, Fujisawa K, Dal Molin M, Sakai N, Matile S.
PMID: 26246986
ChemistryOpen. 2015 Jun;4(3):264-7. doi: 10.1002/open.201402139. Epub 2015 Feb 05.

Monomers with large surface area and high quantum yield, that is fluorescent flippers, have been engineered into twisted push-pull oligomers to create membrane probes with high mechanosensitivity and long fluorescence lifetime. Here, the synthesis and characterization of thieno[3,4]pyrazines and...

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Verolet Q, Soleimanpour S, Fujisawa K, et al. Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems. ChemistryOpen. 2015;4(3):264-7doi: 10.1002/open.201402139.
Verolet, Q., Soleimanpour, S., Fujisawa, K., Dal Molin, M., Sakai, N., & Matile, S. (2015). Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems. ChemistryOpen, 4(3), 264-7. https://doi.org/10.1002/open.201402139
Verolet, Quentin, et al. "Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems." ChemistryOpen vol. 4,3 (2015): 264-7. doi: https://doi.org/10.1002/open.201402139
Verolet Q, Soleimanpour S, Fujisawa K, Dal Molin M, Sakai N, Matile S. Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems. ChemistryOpen. 2015 Jun;4(3):264-7. doi: 10.1002/open.201402139. Epub 2015 Feb 05. PMID: 26246986; PMCID: PMC4522174.
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Chemical and Sensory Characterization of Hydrolyzed Vegetable Protein, a Savory Flavoring.

Journal of agricultural and food chemistry

Aaslyng MD, Martens M, Poll L, Nielsen PM, Flyge H, Larsen LM.
PMID: 10554267
J Agric Food Chem. 1998 Feb 16;46(2):481-489. doi: 10.1021/jf970556e.

Three protein hydrolysates (HVPs) were produced from untoasted defatted soy by acidic hydrolysis (aHVP), enzymatic hydrolysis (eHVP), and enzymatic hydrolysis followed by a heat treatment with glucose (eHVPrea). The three HVPs were characterized by amino acid analysis, identification of...

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Aaslyng MD, Martens M, Poll L, et al. Chemical and Sensory Characterization of Hydrolyzed Vegetable Protein, a Savory Flavoring. J Agric Food Chem. 1998;46(2):481-489doi: 10.1021/jf970556e.
Aaslyng, M. D., Martens, M., Poll, L., Nielsen, P. M., Flyge, H., & Larsen, L. M. (1998). Chemical and Sensory Characterization of Hydrolyzed Vegetable Protein, a Savory Flavoring. Journal of agricultural and food chemistry, 46(2), 481-489. https://doi.org/10.1021/jf970556e
Aaslyng, et al. "Chemical and Sensory Characterization of Hydrolyzed Vegetable Protein, a Savory Flavoring." Journal of agricultural and food chemistry vol. 46,2 (1998): 481-489. doi: https://doi.org/10.1021/jf970556e
Aaslyng MD, Martens M, Poll L, Nielsen PM, Flyge H, Larsen LM. Chemical and Sensory Characterization of Hydrolyzed Vegetable Protein, a Savory Flavoring. J Agric Food Chem. 1998 Feb 16;46(2):481-489. doi: 10.1021/jf970556e. PMID: 10554267.
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Pyrrolodiazines. 2. Structure and Chemistry of Pyrrolo[1,2-a]pyrazine and 1,3-Dipolar Cycloaddition of Its Azomethine Ylides.

The Journal of organic chemistry

Mínguez JM, Castellote MI, Vaquero JJ, García-Navio JL, Alvarez-Builla J, Castaño O, Andrés JL.
PMID: 11667394
J Org Chem. 1996 Jul 12;61(14):4655-4665. doi: 10.1021/jo9600969.

A new synthesis of the pyrrolo[1,2-a]pyrazine system from pyrrole is described. In light of the ab initio calculations carried out on this heterocyclic system some of its basic chemistry was investigated and included electrophilic substitution, addition of organolithium reagents,...

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Mínguez JM, Castellote MI, Vaquero JJ, et al. Pyrrolodiazines. 2. Structure and Chemistry of Pyrrolo[1,2-a]pyrazine and 1,3-Dipolar Cycloaddition of Its Azomethine Ylides. J Org Chem. 1996;61(14):4655-4665doi: 10.1021/jo9600969.
Mínguez, J. M., Castellote, M. I., Vaquero, J. J., García-Navio, J. L., Alvarez-Builla, J., Castaño, O., & Andrés, J. L. (1996). Pyrrolodiazines. 2. Structure and Chemistry of Pyrrolo[1,2-a]pyrazine and 1,3-Dipolar Cycloaddition of Its Azomethine Ylides. The Journal of organic chemistry, 61(14), 4655-4665. https://doi.org/10.1021/jo9600969
Mínguez, José M., et al. "Pyrrolodiazines. 2. Structure and Chemistry of Pyrrolo[1,2-a]pyrazine and 1,3-Dipolar Cycloaddition of Its Azomethine Ylides." The Journal of organic chemistry vol. 61,14 (1996): 4655-4665. doi: https://doi.org/10.1021/jo9600969
Mínguez JM, Castellote MI, Vaquero JJ, García-Navio JL, Alvarez-Builla J, Castaño O, Andrés JL. Pyrrolodiazines. 2. Structure and Chemistry of Pyrrolo[1,2-a]pyrazine and 1,3-Dipolar Cycloaddition of Its Azomethine Ylides. J Org Chem. 1996 Jul 12;61(14):4655-4665. doi: 10.1021/jo9600969. PMID: 11667394.
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Ladderlike oligomers; intramolecular hydrogen bonding, push-pull character, and electron affinity.

Chemistry (Weinheim an der Bergstrasse, Germany)

Pieterse K, Vekemans JA, Kooijman H, Spek AL, Meijer EW.
PMID: 11192093
Chemistry. 2000 Dec 15;6(24):4597-603. doi: 10.1002/1521-3765(20001215)6:24<4597::aid-chem4597>3.0.co;2-4.

Symmetrical 2,5-bis(2-aminophenyl)pyrazines have been synthesized by application of the Stille coupling strategy. These cotrimers feature three important properties, namely strong intramolecular hydrogen bonding, push-pull character, and high electron affinity. The presence of intramolecular hydrogen bonds has been confirmed by...

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Pieterse K, Vekemans JA, Kooijman H, et al. Ladderlike oligomers; intramolecular hydrogen bonding, push-pull character, and electron affinity. Chemistry. 2000;6(24):4597-603doi: 10.1002/1521-3765(20001215)6:24<4597::aid-chem4597>3.0.co;2-4.
Pieterse, K., Vekemans, J. A., Kooijman, H., Spek, A. L., & Meijer, E. W. (2000). Ladderlike oligomers; intramolecular hydrogen bonding, push-pull character, and electron affinity. Chemistry (Weinheim an der Bergstrasse, Germany), 6(24), 4597-603. https://doi.org/10.1002/1521-3765(20001215)6:24<4597::aid-chem4597>3.0.co;2-4
Pieterse, K, et al. "Ladderlike oligomers; intramolecular hydrogen bonding, push-pull character, and electron affinity." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 6,24 (2000): 4597-603. doi: https://doi.org/10.1002/1521-3765(20001215)6:24<4597::aid-chem4597>3.0.co;2-4
Pieterse K, Vekemans JA, Kooijman H, Spek AL, Meijer EW. Ladderlike oligomers; intramolecular hydrogen bonding, push-pull character, and electron affinity. Chemistry. 2000 Dec 15;6(24):4597-603. doi: 10.1002/1521-3765(20001215)6:24<4597::aid-chem4597>3.0.co;2-4. PMID: 11192093.
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Tandem oxidation processes for the preparation of nitrogen-containing heteroaromatic and heterocyclic compounds.

Organic & biomolecular chemistry

Raw SA, Wilfred CD, Taylor RJ.
PMID: 14985820
Org Biomol Chem. 2004 Mar 07;2(5):788-96. doi: 10.1039/b315689c. Epub 2004 Feb 11.

alpha-hydroxy ketones undergo manganese dioxide-mediated oxidation followed by in situ trapping with aromatic or aliphatic 1,2-diamines to give quinoxalines or dihydropyrazines, respectively, in a one-pot procedure which avoids the need to isolate the highly reactive dicarbonyl intermediates. The scope...

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Raw SA, Wilfred CD, Taylor RJ. Tandem oxidation processes for the preparation of nitrogen-containing heteroaromatic and heterocyclic compounds. Org Biomol Chem. 2004;2(5):788-96doi: 10.1039/b315689c.
Raw, S. A., Wilfred, C. D., & Taylor, R. J. (2004). Tandem oxidation processes for the preparation of nitrogen-containing heteroaromatic and heterocyclic compounds. Organic & biomolecular chemistry, 2(5), 788-96. https://doi.org/10.1039/b315689c
Raw, Steven A, et al. "Tandem oxidation processes for the preparation of nitrogen-containing heteroaromatic and heterocyclic compounds." Organic & biomolecular chemistry vol. 2,5 (2004): 788-96. doi: https://doi.org/10.1039/b315689c
Raw SA, Wilfred CD, Taylor RJ. Tandem oxidation processes for the preparation of nitrogen-containing heteroaromatic and heterocyclic compounds. Org Biomol Chem. 2004 Mar 07;2(5):788-96. doi: 10.1039/b315689c. Epub 2004 Feb 11. PMID: 14985820.
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Showing 1 to 12 of 208 entries