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Showing 1 to 12 of 102 entries
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Central mediators involved in the febrile response: effects of antipyretic drugs.

Temperature (Austin, Tex.)

Zampronio AR, Soares DM, Souza GE.
PMID: 27227071
Temperature (Austin). 2015 Oct 13;2(4):506-21. doi: 10.1080/23328940.2015.1102802. eCollection 2015.

Fever is a complex signal of inflammatory and infectious diseases. It is generally initiated when peripherally produced endogenous pyrogens reach areas that surround the hypothalamus. These peripheral endogenous pyrogens are cytokines that are produced by leukocytes and other cells,...

Application of genomic tools in plant breeding.

Current genomics

Pérez-de-Castro AM, Vilanova S, Cañizares J, Pascual L, Blanca JM, Díez MJ, Prohens J, Picó B.
PMID: 23115520
Curr Genomics. 2012 May;13(3):179-95. doi: 10.2174/138920212800543084.

Plant breeding has been very successful in developing improved varieties using conventional tools and methodologies. Nowadays, the availability of genomic tools and resources is leading to a new revolution of plant breeding, as they facilitate the study of the...

Quality control of positron emission tomography radiopharmaceuticals: An institutional experience.

Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

Shukla J, Vatsa R, Garg N, Bhusari P, Watts A, Mittal BR.
PMID: 24379528
Indian J Nucl Med. 2013 Oct;28(4):200-6. doi: 10.4103/0972-3919.121963.

PURPOSE OF THE STUDY: To study quality control parameters of routinely prepared positron emission tomography (PET) radiopharmaceuticals.MATERIALS AND METHODS: Three PET radiopharmaceuticals fluorine-18 fluorodeoxyglucose (F-18 FDG), N-13 ammonia (N-13 NH3), and Ga-68 DOTATATE (n = 25 each), prepared by...

[First Results in the prevaluation of the human whole blood assay for pyrogens in biological pharmaceuticals].

ALTEX

Fischer M, Hartzsch K, Hartung T, Montag-Lessing T.
PMID: 11178527
ALTEX. 1998;15(5):10-13.

When establishing the whole blood assay for pyrogens in our laboratory we did several investigations on the standard pyrogen to be used. Because of the hydrophobicity of the lipopolysaccharid (LPS) it is difficult to get a homogeneous solution. Therefore...

[Development of a pyrogen test based on rabbit blood].

ALTEX

Hartung T, Crameri R, Wendel A.
PMID: 11178529
ALTEX. 1998;15(5):17-18.

The testing of drugs for pyrogen contamination e.g. the exclusion of fever inducing impurities, was standardised in the Forties in the form of animal pyrogen assay. We recently proposed an alternative method using human whole blood from healthy donors....

An Effective Fluorescent Sensor for Choline-Containing Phospholipids.

Angewandte Chemie (International ed. in English)

Tomàs S, Prohens R, Deslongchamps G, Ballester P, Costa A.
PMID: 10425484
Angew Chem Int Ed Engl. 1999 Aug;38(15):2208-2211. doi: 10.1002/(sici)1521-3773(19990802)38:15<2208::aid-anie2208>3.0.co;2-9.

A set of weak CH small middle dot small middle dot small middle dotO interactions is responsible for the recognition of tetraalkylammonium ions (ball-and-stick structure) by the tripodal receptors depicted in the diagram, in which the binding pocket is...

THE DESTRUCTION OF PYROGENS BY HYDROGEN PEROXIDE.

Science (New York, N.Y.)

Campbell DH, Cherkin A.
PMID: 17730020
Science. 1945 Nov 23;102(2656):535-6. doi: 10.1126/science.102.2656.535.

No abstract available.

Molecular aspects of fever and hyperthermia.

Immunology and allergy clinics of North America

Roth J, Rummel C, Barth SW, Gerstberger R, Hübschle T.
PMID: 19389579
Immunol Allergy Clin North Am. 2009 May;29(2):229-45. doi: 10.1016/j.iac.2009.02.005.

After defining hyperthermia and fever, this article describes the complete chain of events leading to the genesis of fever, starting with the lipopolysaccharide-induced formation of endogenous pyrogens (cytokines), their interactions with relevant targets in the brain, the induction of...

Reduced febrile responses to peripheral and central administration of pyrogen in aged squirrel monkeys.

Neurobiology of aging

Clark SM, Gean JT, Lipton JM.
PMID: 24279943
Neurobiol Aging. 1980;1(2):175-80. doi: 10.1016/0197-4580(80)90013-5.

There is long-standing controversy as to whether fever capacity is reduced in aged man. Although loss of this cardinal sign of disease would be an impediment to diagnosis and treatment, there has been no previous research on altered febrile...

Quality-control analytical methods: endotoxins: essential testing for pyrogens in the compounding laboratory, part2.

International journal of pharmaceutical compounding

Cooper JF, Chakrabarty K, McGuire J, Zolner WJ, Jones V, Hedman H.
PMID: 23965654
Int J Pharm Compd. 2010 Nov-Dec;14(6):493-506.

Ensuring that the endotoxin burden in sterile preparations is within allowable limits is one of the greatest challenges faced by compounding pharmacists. Today, endotoxin analyses can be performed in the pharmacy with a test kit or accomplished by sending...

Quality-control analytical methods: endtoxins: essential testing for pyrogens in the compounding laboratory, part 1.

International journal of pharmaceutical compounding

Dubczak J, Latta KS, Hedman H, Smith DR.
PMID: 23965585
Int J Pharm Compd. 2010 Sep-Oct;14(5):407-14.

Inadvertent exposure to endotoxins administered intravenously, intramuscularly, or intrathecally can cause a constellation of adverse effects that range from fever to multiple organ failure and death. Pharmacists who compound sterile formulations must remain exceptionally vigilant to guard against the...

Fever in Children: Should it be Treated?.

Canadian family physician Medecin de famille canadien

Habbick BF.
PMID: 21253180
Can Fam Physician. 1988 May;34:1161-4.

Fever, which is the regulation of body temperature at an elevated level, must be differentiated from hyperthermia. The pathogenesis of fever involves exogenous pyrogens acting on macrophages/monocytes to produce the endogenous pyrogen, interleukin-1, which acts on the thermoregulatory centre...

Showing 1 to 12 of 102 entries