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Showing 1 to 12 of 27 entries
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Variation in the Tropane Alkaloid Content of Hyoscyamus muticus Plants and Cell Culture Clones.

Planta medica

Oksman-Caldentey KM, Vuorela H, Strauß A, Hiltunen R.
PMID: 17269041
Planta Med. 1987 Aug;53(4):349-54. doi: 10.1055/s-2006-962736.

Systematic studies were carried out on two different strains (Gatersleben and Cairo) of HYOSCYAMUS MUTICUS L. (Solananaceae) in order to analyse the variation in the contents of the two main tropa-alkaloids in individual plants and protoplast-derived cell culture clones....

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Oksman-Caldentey KM, Vuorela H, Strauß A, et al. Variation in the Tropane Alkaloid Content of Hyoscyamus muticus Plants and Cell Culture Clones. Planta Med. 1987;53(4):349-54doi: 10.1055/s-2006-962736.
Oksman-Caldentey, K. M., Vuorela, H., Strauß, A., & Hiltunen, R. (1987). Variation in the Tropane Alkaloid Content of Hyoscyamus muticus Plants and Cell Culture Clones. Planta medica, 53(4), 349-54. https://doi.org/10.1055/s-2006-962736
Oksman-Caldentey, K M, et al. "Variation in the Tropane Alkaloid Content of Hyoscyamus muticus Plants and Cell Culture Clones." Planta medica vol. 53,4 (1987): 349-54. doi: https://doi.org/10.1055/s-2006-962736
Oksman-Caldentey KM, Vuorela H, Strauß A, Hiltunen R. Variation in the Tropane Alkaloid Content of Hyoscyamus muticus Plants and Cell Culture Clones. Planta Med. 1987 Aug;53(4):349-54. doi: 10.1055/s-2006-962736. PMID: 17269041.
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Regulation of putative muscarinic cholinergic receptor subtypes in rat brain.

Neurochemistry international

Norman AB, Battaglia G, Creese I.
PMID: 20493134
Neurochem Int. 1986;9(2):337-47. doi: 10.1016/0197-0186(86)90071-9.

Transection of the fimbria/fornix, producing a 75% reduction in the activity of the cholinergic marker choline-o-acetyltransferase (CAT EC. 2.3.1.6) in rat hippocampus, did not change the binding characteristics of the non-subtype selective, muscarinic cholinergic receptor antagonist ligand [(3)H](?)quinuclidinyl benzilate...

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Norman AB, Battaglia G, Creese I. Regulation of putative muscarinic cholinergic receptor subtypes in rat brain. Neurochem Int. 1986;9(2):337-47doi: 10.1016/0197-0186(86)90071-9.
Norman, A. B., Battaglia, G., & Creese, I. (1986). Regulation of putative muscarinic cholinergic receptor subtypes in rat brain. Neurochemistry international, 9(2), 337-47. https://doi.org/10.1016/0197-0186(86)90071-9
Norman, A B, et al. "Regulation of putative muscarinic cholinergic receptor subtypes in rat brain." Neurochemistry international vol. 9,2 (1986): 337-47. doi: https://doi.org/10.1016/0197-0186(86)90071-9
Norman AB, Battaglia G, Creese I. Regulation of putative muscarinic cholinergic receptor subtypes in rat brain. Neurochem Int. 1986;9(2):337-47. doi: 10.1016/0197-0186(86)90071-9. PMID: 20493134.
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Properties of putative nicotinic and muscarinic cholinergic receptors in the central nervous system of Locusta migratoria.

Neurochemistry international

Breer H.
PMID: 20487807
Neurochem Int. 1981 Mar;3(1):43-52. doi: 10.1016/0197-0186(81)90048-6.

Nervous tissue preparations from Locusta migratoria specifically bind potent nicotinic (?-bungarotoxin) and muscarinic (quinuclidinyl benzilate) ligands. Binding properties and pharmacological data indicate that the central nervous system of the locust contains at least two distinct classes of receptors. Subcellular...

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Breer H. Properties of putative nicotinic and muscarinic cholinergic receptors in the central nervous system of Locusta migratoria. Neurochem Int. 1981;3(1):43-52doi: 10.1016/0197-0186(81)90048-6.
Breer, H. (1981). Properties of putative nicotinic and muscarinic cholinergic receptors in the central nervous system of Locusta migratoria. Neurochemistry international, 3(1), 43-52. https://doi.org/10.1016/0197-0186(81)90048-6
Breer, H. "Properties of putative nicotinic and muscarinic cholinergic receptors in the central nervous system of Locusta migratoria." Neurochemistry international vol. 3,1 (1981): 43-52. doi: https://doi.org/10.1016/0197-0186(81)90048-6
Breer H. Properties of putative nicotinic and muscarinic cholinergic receptors in the central nervous system of Locusta migratoria. Neurochem Int. 1981 Mar;3(1):43-52. doi: 10.1016/0197-0186(81)90048-6. PMID: 20487807.
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Unilateral decortication affects muscarinic cholinergic receptor binding in rat basal forebrain.

Neurochemistry international

Schliebs R, Stewart MG.
PMID: 20504543
Neurochem Int. 1990;16(1):81-7. doi: 10.1016/0197-0186(90)90126-e.

The distribution of muscarinic acetylcholine receptors (including the M(1)-receptor subtype), beta-adreno receptors, and noradrenaline uptake sites was studied in cholinergic basal forebrain nuclei (medial and lateral septum, ventral and dorsal limb of the diagonal band, substantia innominata and nucleus...

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Schliebs R, Stewart MG. Unilateral decortication affects muscarinic cholinergic receptor binding in rat basal forebrain. Neurochem Int. 1990;16(1):81-7doi: 10.1016/0197-0186(90)90126-e.
Schliebs, R., & Stewart, M. G. (1990). Unilateral decortication affects muscarinic cholinergic receptor binding in rat basal forebrain. Neurochemistry international, 16(1), 81-7. https://doi.org/10.1016/0197-0186(90)90126-e
Schliebs, R, and Stewart, M G. "Unilateral decortication affects muscarinic cholinergic receptor binding in rat basal forebrain." Neurochemistry international vol. 16,1 (1990): 81-7. doi: https://doi.org/10.1016/0197-0186(90)90126-e
Schliebs R, Stewart MG. Unilateral decortication affects muscarinic cholinergic receptor binding in rat basal forebrain. Neurochem Int. 1990;16(1):81-7. doi: 10.1016/0197-0186(90)90126-e. PMID: 20504543.
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Two-step isomerization of quinuclidinyl benzilate-muscarinic receptor complex.

Neurochemistry international

Eller M, Järv J.
PMID: 20501231
Neurochem Int. 1988;12(3):285-9. doi: 10.1016/0197-0186(88)90166-0.

A kinetic analysis was made of the dissociation reaction of the muscarinic receptor-l-[(3)H]quinuclidinyl benzilate complex at 25 degrees C in 0.05 M K-phosphate buffer. The course of the reaction was followed by the decrease in the concentration of the...

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Eller M, Järv J. Two-step isomerization of quinuclidinyl benzilate-muscarinic receptor complex. Neurochem Int. 1988;12(3):285-9doi: 10.1016/0197-0186(88)90166-0.
Eller, M., & Järv, J. (1988). Two-step isomerization of quinuclidinyl benzilate-muscarinic receptor complex. Neurochemistry international, 12(3), 285-9. https://doi.org/10.1016/0197-0186(88)90166-0
Eller, M, and Järv, J. "Two-step isomerization of quinuclidinyl benzilate-muscarinic receptor complex." Neurochemistry international vol. 12,3 (1988): 285-9. doi: https://doi.org/10.1016/0197-0186(88)90166-0
Eller M, Järv J. Two-step isomerization of quinuclidinyl benzilate-muscarinic receptor complex. Neurochem Int. 1988;12(3):285-9. doi: 10.1016/0197-0186(88)90166-0. PMID: 20501231.
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Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex.

Neurochemistry international

Moret C, Pastrie I, Briley M.
PMID: 20504503
Neurochem Int. 1989;15(3):333-7. doi: 10.1016/0197-0186(89)90141-1.

The effect of chronic scopolamine on muscarinic receptors in rat frontoparietal cortex was investigated by measuring the specific binding of [(3)H](?)quinuclidinyl benzilate and [ (3)H ](+)-cis- methyldioxolane . Administration of the muscarinic antagonist, scopolamine (10 mg/kg/day i.p.) for 21...

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Moret C, Pastrie I, Briley M. Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex. Neurochem Int. 1989;15(3):333-7doi: 10.1016/0197-0186(89)90141-1.
Moret, C., Pastrie, I., & Briley, M. (1989). Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex. Neurochemistry international, 15(3), 333-7. https://doi.org/10.1016/0197-0186(89)90141-1
Moret, C, et al. "Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex." Neurochemistry international vol. 15,3 (1989): 333-7. doi: https://doi.org/10.1016/0197-0186(89)90141-1
Moret C, Pastrie I, Briley M. Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex. Neurochem Int. 1989;15(3):333-7. doi: 10.1016/0197-0186(89)90141-1. PMID: 20504503.
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Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication.

Neurochemistry international

Earley B, Biegon A, Leonard BE.
PMID: 20504522
Neurochem Int. 1989;15(4):475-83. doi: 10.1016/0197-0186(89)90166-6.

The influence of trimethyl tin (TMT) intoxication on muscarinic cholinergic receptors and histochemistry of acetylcholinesterase (AChE) in the rat brain 21 days after treatment was studied. The topographical distribution and reduction in muscarinic receptor sites were analysed by means...

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Earley B, Biegon A, Leonard BE. Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication. Neurochem Int. 1989;15(4):475-83doi: 10.1016/0197-0186(89)90166-6.
Earley, B., Biegon, A., & Leonard, B. E. (1989). Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication. Neurochemistry international, 15(4), 475-83. https://doi.org/10.1016/0197-0186(89)90166-6
Earley, B, et al. "Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication." Neurochemistry international vol. 15,4 (1989): 475-83. doi: https://doi.org/10.1016/0197-0186(89)90166-6
Earley B, Biegon A, Leonard BE. Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication. Neurochem Int. 1989;15(4):475-83. doi: 10.1016/0197-0186(89)90166-6. PMID: 20504522.
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Effect of NG-nitro-L-arginine methyl ester, a nitric oxide synthase inhibitor, on neurotransmitter receptor systems in aged rats.

European journal of neurology

Araki T, Itoyama Y, Kato H, Oshima Y, Shuto K.
PMID: 10210896
Eur J Neurol. 1998 Nov;5(6):601-608. doi: 10.1046/j.1468-1331.1998.560601.x.

In order to examine the effect of age and nitric oxide synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME), we studied the changes on major neurotransmitter receptor systems in 6 (adult) and 24-month-old (aged) Fischer male rats using receptor autoradiography. L-NAME...

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Araki T, Itoyama Y, Kato H, et al. Effect of NG-nitro-L-arginine methyl ester, a nitric oxide synthase inhibitor, on neurotransmitter receptor systems in aged rats. Eur J Neurol. 1998;5(6):601-608doi: 10.1046/j.1468-1331.1998.560601.x.
Araki, T., Itoyama, Y., Kato, H., Oshima, Y., & Shuto, K. (1998). Effect of NG-nitro-L-arginine methyl ester, a nitric oxide synthase inhibitor, on neurotransmitter receptor systems in aged rats. European journal of neurology, 5(6), 601-608. https://doi.org/10.1046/j.1468-1331.1998.560601.x
Araki, et al. "Effect of NG-nitro-L-arginine methyl ester, a nitric oxide synthase inhibitor, on neurotransmitter receptor systems in aged rats." European journal of neurology vol. 5,6 (1998): 601-608. doi: https://doi.org/10.1046/j.1468-1331.1998.560601.x
Araki T, Itoyama Y, Kato H, Oshima Y, Shuto K. Effect of NG-nitro-L-arginine methyl ester, a nitric oxide synthase inhibitor, on neurotransmitter receptor systems in aged rats. Eur J Neurol. 1998 Nov;5(6):601-608. doi: 10.1046/j.1468-1331.1998.560601.x. PMID: 10210896.
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3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats.

Basic & clinical pharmacology & toxicology

Dlabkova A, Herman D, Cechova L, Hroch M, Vanova N, Zdarova Karasova J.
PMID: 34145973
Basic Clin Pharmacol Toxicol. 2021 Sep;129(3):246-255. doi: 10.1111/bcpt.13627. Epub 2021 Jun 30.

3-Quinuclidinyl benzilate (BZ) ranks among incapacitating military warfare agents. It acts as a competitive inhibitor on muscarinic receptors leading to non-lethal mental impairment. The present study aimed to investigate toxicokinetics of BZ in rats. Moreover, BZ can be exploited...

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Dlabkova A, Herman D, Cechova L, et al. 3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats. Basic Clin Pharmacol Toxicol. 2021;129(3):246-255doi: 10.1111/bcpt.13627.
Dlabkova, A., Herman, D., Cechova, L., Hroch, M., Vanova, N., & Zdarova Karasova, J. (2021). 3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats. Basic & clinical pharmacology & toxicology, 129(3), 246-255. https://doi.org/10.1111/bcpt.13627
Dlabkova, Alzbeta, et al. "3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats." Basic & clinical pharmacology & toxicology vol. 129,3 (2021): 246-255. doi: https://doi.org/10.1111/bcpt.13627
Dlabkova A, Herman D, Cechova L, Hroch M, Vanova N, Zdarova Karasova J. 3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats. Basic Clin Pharmacol Toxicol. 2021 Sep;129(3):246-255. doi: 10.1111/bcpt.13627. Epub 2021 Jun 30. PMID: 34145973.
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Effects of vinconate on neurotransmitter receptor systems in aged rat brain.

Environmental toxicology and pharmacology

Araki T, Kato H, Shuto K, Fujiwara T, Itoyama Y.
PMID: 21781741
Environ Toxicol Pharmacol. 1996 Dec 20;2(4):343-9. doi: 10.1016/s1382-6689(96)00068-3.

We investigated the effects of age and (±)-methyl-3-ethyl-2,3,3a,4-tetrahydro-1 H-indolo[3,2,1-de][1,5]naphthyridine-6-carboxylate hydrochloride (vinconate), an indolonaphthyridine derivative, on neurotransmitter receptor systems in the rat brain using quantitative receptor autoradiography. [(3)H]Quinuclidinyl benzilate (QNB), [(3)H]hemicholinium-3 (HC) and [(3)H]muscimol were used to label acetylcholine receptors,...

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Araki T, Kato H, Shuto K, et al. Effects of vinconate on neurotransmitter receptor systems in aged rat brain. Environ Toxicol Pharmacol. 1996;2(4):343-9doi: 10.1016/s1382-6689(96)00068-3.
Araki, T., Kato, H., Shuto, K., Fujiwara, T., & Itoyama, Y. (1996). Effects of vinconate on neurotransmitter receptor systems in aged rat brain. Environmental toxicology and pharmacology, 2(4), 343-9. https://doi.org/10.1016/s1382-6689(96)00068-3
Araki, T, et al. "Effects of vinconate on neurotransmitter receptor systems in aged rat brain." Environmental toxicology and pharmacology vol. 2,4 (1996): 343-9. doi: https://doi.org/10.1016/s1382-6689(96)00068-3
Araki T, Kato H, Shuto K, Fujiwara T, Itoyama Y. Effects of vinconate on neurotransmitter receptor systems in aged rat brain. Environ Toxicol Pharmacol. 1996 Dec 20;2(4):343-9. doi: 10.1016/s1382-6689(96)00068-3. PMID: 21781741.
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Kinetic aspects of l-quinuclidinyl benzilate interaction with muscarinic receptor.

Neurochemistry international

Järv J, Eller M.
PMID: 20501298
Neurochem Int. 1988;13(4):419-28. doi: 10.1016/0197-0186(88)90069-1.

l-Quinuclidinyl benzilate is undoubtedly the most widely used radioactive reporter ligand for studies on muscarinic receptor. In the present Commentary the kinetic aspects of the interaction of this ligand with muscarinic receptor are summarized. On the basis of these...

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Järv J, Eller M. Kinetic aspects of l-quinuclidinyl benzilate interaction with muscarinic receptor. Neurochem Int. 1988;13(4):419-28doi: 10.1016/0197-0186(88)90069-1.
Järv, J., & Eller, M. (1988). Kinetic aspects of l-quinuclidinyl benzilate interaction with muscarinic receptor. Neurochemistry international, 13(4), 419-28. https://doi.org/10.1016/0197-0186(88)90069-1
Järv, J, and Eller, M. "Kinetic aspects of l-quinuclidinyl benzilate interaction with muscarinic receptor." Neurochemistry international vol. 13,4 (1988): 419-28. doi: https://doi.org/10.1016/0197-0186(88)90069-1
Järv J, Eller M. Kinetic aspects of l-quinuclidinyl benzilate interaction with muscarinic receptor. Neurochem Int. 1988;13(4):419-28. doi: 10.1016/0197-0186(88)90069-1. PMID: 20501298.
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Muscarinic pharmacology of the inhibition of adenylate cyclase in N18TG2 neuroblastoma cells.

Neurochemistry international

Bidaut-Russell M, Howlett AC.
PMID: 20501173
Neurochem Int. 1987;11(3):287-92. doi: 10.1016/0197-0186(87)90048-9.

This study characterizes the muscarinic cholinergic receptors associated with the inhibition of adenylate cyclase on N18TG2 neuroblastoma cell membranes. Agonists could be divided into two classes: oxotremorine, acetylcholine, carbachol and arecoline exerted the most efficacious and potent inhibition, while...

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Bidaut-Russell M, Howlett AC. Muscarinic pharmacology of the inhibition of adenylate cyclase in N18TG2 neuroblastoma cells. Neurochem Int. 1987;11(3):287-92doi: 10.1016/0197-0186(87)90048-9.
Bidaut-Russell, M., & Howlett, A. C. (1987). Muscarinic pharmacology of the inhibition of adenylate cyclase in N18TG2 neuroblastoma cells. Neurochemistry international, 11(3), 287-92. https://doi.org/10.1016/0197-0186(87)90048-9
Bidaut-Russell, M, and Howlett, A C. "Muscarinic pharmacology of the inhibition of adenylate cyclase in N18TG2 neuroblastoma cells." Neurochemistry international vol. 11,3 (1987): 287-92. doi: https://doi.org/10.1016/0197-0186(87)90048-9
Bidaut-Russell M, Howlett AC. Muscarinic pharmacology of the inhibition of adenylate cyclase in N18TG2 neuroblastoma cells. Neurochem Int. 1987;11(3):287-92. doi: 10.1016/0197-0186(87)90048-9. PMID: 20501173.
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Showing 1 to 12 of 27 entries