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Differential hyperpolarization to substance P and calcitonin gene-related peptide in smooth muscle versus endothelium of mouse mesenteric artery.

Microcirculation (New York, N.Y. : 1994)

Norton CE, Boerman EM, Segal SS.
PMID: 34633728
Microcirculation. 2021 Nov;28(8):e12733. doi: 10.1111/micc.12733. Epub 2021 Oct 21.

OBJECTIVE: We sought to define how sensory neurotransmitters substance P and calcitonin gene-related peptide (CGRP) affect membrane potential of vascular smooth muscle and endothelium.METHODS: Microelectrodes recorded membrane potential of smooth muscle from pressurized mouse mesenteric arteries (diameter, ~150 µm)...

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