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The impact of cardiac loading on a novel metric of left ventricular diastolic function in healthy middle-aged adults: Systolic-diastolic coupling.

Physiological reports

MacNamara JP, Koshti V, Dias KA, Howden E, Hearon CM, Cheng IJ, Hynan LS, Levine BD, Sarma S.
PMID: 34873864
Physiol Rep. 2021 Dec;9(23):e15129. doi: 10.14814/phy2.15129.

AIMS: Left ventricular (LV) restoring forces are primed by ventricular deformation during systole and contribute to cardiac relaxation and early diastolic suction. Systolic-diastolic coupling, the relationship between systolic contraction and diastolic recoil, is a novel marker of restoring forces,...

The impact of cardiac loading on a novel metric of left ventricular diastolic function in healthy middle-aged adults: Systolic-diastolic coupling.

Physiological reports

MacNamara JP, Koshti V, Dias KA, Howden E, Hearon CM, Cheng IJ, Hynan LS, Levine BD, Sarma S.
PMID: 34873864
Physiol Rep. 2021 Dec;9(23):e15129. doi: 10.14814/phy2.15129.

AIMS: Left ventricular (LV) restoring forces are primed by ventricular deformation during systole and contribute to cardiac relaxation and early diastolic suction. Systolic-diastolic coupling, the relationship between systolic contraction and diastolic recoil, is a novel marker of restoring forces,...

Central Command and the Regulation of Exercise Heart Rate Response in Heart Failure With Preserved Ejection Fraction.

Circulation

Sarma S, Howden E, Lawley J, Samels M, Levine BD.
PMID: 33205661
Circulation. 2021 Feb 23;143(8):783-789. doi: 10.1161/CIRCULATIONAHA.120.048338. Epub 2020 Nov 18.

BACKGROUND: Chronotropic incompetence is common in heart failure with preserved ejection fraction (HFpEF) and is linked to impaired aerobic capacity. Whether upstream autonomic signaling pathways responsible for raising exercise heart rate are impaired in HFpEF is unknown. We investigated...

Central Command and the Regulation of Exercise Heart Rate Response in Heart Failure With Preserved Ejection Fraction.

Circulation

Sarma S, Howden E, Lawley J, Samels M, Levine BD.
PMID: 33205661
Circulation. 2021 Feb 23;143(8):783-789. doi: 10.1161/CIRCULATIONAHA.120.048338. Epub 2020 Nov 18.

BACKGROUND: Chronotropic incompetence is common in heart failure with preserved ejection fraction (HFpEF) and is linked to impaired aerobic capacity. Whether upstream autonomic signaling pathways responsible for raising exercise heart rate are impaired in HFpEF is unknown. We investigated...

Showing 1 to 4 of 4 entries