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Exercise intolerance.

Cardiology clinics

Kitzman DW, Groban L.
PMID: 21803233
Cardiol Clin. 2011 Aug;29(3):461-77. doi: 10.1016/j.ccl.2011.06.002.

Exercise intolerance is the primary symptom of chronic diastolic heart failure. It is part of the definition of heart failure and is intimately linked to its pathophysiology. Further, exercise intolerance affects the diagnosis and prognosis of heart failure. In...

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Kitzman DW, Groban L. Exercise intolerance. Cardiol Clin. 2011;29(3):461-77doi: 10.1016/j.ccl.2011.06.002.
Kitzman, D. W., & Groban, L. (2011). Exercise intolerance. Cardiology clinics, 29(3), 461-77. https://doi.org/10.1016/j.ccl.2011.06.002
Kitzman, Dalane W, and Groban, Leanne. "Exercise intolerance." Cardiology clinics vol. 29,3 (2011): 461-77. doi: https://doi.org/10.1016/j.ccl.2011.06.002
Kitzman DW, Groban L. Exercise intolerance. Cardiol Clin. 2011 Aug;29(3):461-77. doi: 10.1016/j.ccl.2011.06.002. PMID: 21803233; PMCID: PMC3694583.
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Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review.

Journal of the American College of Cardiology

Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D.
PMID: 34503685
J Am Coll Cardiol. 2021 Sep 14;78(11):1166-1187. doi: 10.1016/j.jacc.2021.07.014.

Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved ejection fraction (HFpEF), the most common form of heart failure among older individuals. The recent recognition that HFpEF is likely a systemic, multiorgan disorder that shares...

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Pandey A, Shah SJ, Butler J, et al. Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021;78(11):1166-1187doi: 10.1016/j.jacc.2021.07.014.
Pandey, A., Shah, S. J., Butler, J., Kellogg, D. L., Lewis, G. D., Forman, D. E., Mentz, R. J., Borlaug, B. A., Simon, M. A., Chirinos, J. A., Fielding, R. A., Volpi, E., Molina, A. J. A., Haykowsky, M. J., Sam, F., Goodpaster, B. H., Bertoni, A. G., Justice, J. N., White, J. P., Ding, J., Hummel, S. L., LeBrasseur, N. K., Taffet, G. E., Pipinos, I. I., & Kitzman, D. (2021). Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 78(11), 1166-1187. https://doi.org/10.1016/j.jacc.2021.07.014
Pandey, Ambarish, et al. "Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review." Journal of the American College of Cardiology vol. 78,11 (2021): 1166-1187. doi: https://doi.org/10.1016/j.jacc.2021.07.014
Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D. Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 Sep 14;78(11):1166-1187. doi: 10.1016/j.jacc.2021.07.014. PMID: 34503685; PMCID: PMC8525886.
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Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review.

Journal of the American College of Cardiology

Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D.
PMID: 34503685
J Am Coll Cardiol. 2021 Sep 14;78(11):1166-1187. doi: 10.1016/j.jacc.2021.07.014.

Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved ejection fraction (HFpEF), the most common form of heart failure among older individuals. The recent recognition that HFpEF is likely a systemic, multiorgan disorder that shares...

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Pandey A, Shah SJ, Butler J, et al. Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021;78(11):1166-1187doi: 10.1016/j.jacc.2021.07.014.
Pandey, A., Shah, S. J., Butler, J., Kellogg, D. L., Lewis, G. D., Forman, D. E., Mentz, R. J., Borlaug, B. A., Simon, M. A., Chirinos, J. A., Fielding, R. A., Volpi, E., Molina, A. J. A., Haykowsky, M. J., Sam, F., Goodpaster, B. H., Bertoni, A. G., Justice, J. N., White, J. P., Ding, J., Hummel, S. L., LeBrasseur, N. K., Taffet, G. E., Pipinos, I. I., & Kitzman, D. (2021). Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 78(11), 1166-1187. https://doi.org/10.1016/j.jacc.2021.07.014
Pandey, Ambarish, et al. "Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review." Journal of the American College of Cardiology vol. 78,11 (2021): 1166-1187. doi: https://doi.org/10.1016/j.jacc.2021.07.014
Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D. Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 Sep 14;78(11):1166-1187. doi: 10.1016/j.jacc.2021.07.014. PMID: 34503685; PMCID: PMC8525886.
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Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART.

Hypertension (Dallas, Tex. : 1979)

Upadhya B, Pajewski NM, Rocco MV, Hundley WG, Aurigemma G, Hamilton CA, Bates JT, He J, Chen J, Chonchol M, Glasser SP, Hung AM, Pisoni R, Punzi H, Supiano MA, Toto R, Taylor A, Kitzman DW.
PMID: 33775127
Hypertension. 2021 May 05;77(5):1571-1580. doi: 10.1161/HYPERTENSIONAHA.120.16676. Epub 2021 Mar 29.

[Figure: see text].

Cite
Upadhya B, Pajewski NM, Rocco MV, et al. Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. Hypertension. 2021;77(5):1571-1580doi: 10.1161/HYPERTENSIONAHA.120.16676.
Upadhya, B., Pajewski, N. M., Rocco, M. V., Hundley, W. G., Aurigemma, G., Hamilton, C. A., Bates, J. T., He, J., Chen, J., Chonchol, M., Glasser, S. P., Hung, A. M., Pisoni, R., Punzi, H., Supiano, M. A., Toto, R., Taylor, A., Kitzman, D. W. (2021). Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. Hypertension (Dallas, Tex. : 1979), 77(5), 1571-1580. https://doi.org/10.1161/HYPERTENSIONAHA.120.16676
Upadhya, Bharathi, et al. "Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART." Hypertension (Dallas, Tex. : 1979) vol. 77,5 (2021): 1571-1580. doi: https://doi.org/10.1161/HYPERTENSIONAHA.120.16676
Upadhya B, Pajewski NM, Rocco MV, Hundley WG, Aurigemma G, Hamilton CA, Bates JT, He J, Chen J, Chonchol M, Glasser SP, Hung AM, Pisoni R, Punzi H, Supiano MA, Toto R, Taylor A, Kitzman DW. Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. Hypertension. 2021 May 05;77(5):1571-1580. doi: 10.1161/HYPERTENSIONAHA.120.16676. Epub 2021 Mar 29. PMID: 33775127; PMCID: PMC8035296.
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Older Patients With Acute Decompensated Heart Failure Who Live Alone: An Analysis From the REHAB-HF Trial.

Journal of cardiac failure

Warraich HJ, Kitzman DW, Nelson MB, Mentz RJ, Rosenberg PB, Lev Y, Whellan DJ.
PMID: 34147611
J Card Fail. 2021 Jun 18; doi: 10.1016/j.cardfail.2021.06.005. Epub 2021 Jun 18.

No abstract available.

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Warraich HJ, Kitzman DW, Nelson MB, et al. Older Patients With Acute Decompensated Heart Failure Who Live Alone: An Analysis From the REHAB-HF Trial. J Card Fail. 2021;doi: 10.1016/j.cardfail.2021.06.005.
Warraich, H. J., Kitzman, D. W., Nelson, M. B., Mentz, R. J., Rosenberg, P. B., Lev, Y., & Whellan, D. J. (2021). Older Patients With Acute Decompensated Heart Failure Who Live Alone: An Analysis From the REHAB-HF Trial. Journal of cardiac failure, . https://doi.org/10.1016/j.cardfail.2021.06.005
Warraich, Haider J, et al. "Older Patients With Acute Decompensated Heart Failure Who Live Alone: An Analysis From the REHAB-HF Trial." Journal of cardiac failure vol. (2021). doi: https://doi.org/10.1016/j.cardfail.2021.06.005
Warraich HJ, Kitzman DW, Nelson MB, Mentz RJ, Rosenberg PB, Lev Y, Whellan DJ. Older Patients With Acute Decompensated Heart Failure Who Live Alone: An Analysis From the REHAB-HF Trial. J Card Fail. 2021 Jun 18; doi: 10.1016/j.cardfail.2021.06.005. Epub 2021 Jun 18. PMID: 34147611; PMCID: PMC8734952.
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Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction.

Circulation. Heart failure

Anderson T, Cascino TM, Koelling TM, Perry D, Grafton G, Houston DK, Upadhya B, Kitzman DW, Hummel SL.
PMID: 34344169
Circ Heart Fail. 2021 Aug;14(8):e007962. doi: 10.1161/CIRCHEARTFAILURE.120.007962. Epub 2021 Aug 04.

BACKGROUND: Obesity is common in heart failure with preserved ejection fraction (HFpEF), and a hypocaloric diet can improve functional capacity. Malnutrition, sarcopenia, and frailty are also frequently present, and calorie restriction could harm some patients. Resting metabolic rate (RMR)...

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Anderson T, Cascino TM, Koelling TM, et al. Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2021;14(8):e007962doi: 10.1161/CIRCHEARTFAILURE.120.007962.
Anderson, T., Cascino, T. M., Koelling, T. M., Perry, D., Grafton, G., Houston, D. K., Upadhya, B., Kitzman, D. W., & Hummel, S. L. (2021). Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction. Circulation. Heart failure, 14(8), e007962. https://doi.org/10.1161/CIRCHEARTFAILURE.120.007962
Anderson, Theresa, et al. "Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction." Circulation. Heart failure vol. 14,8 (2021): e007962. doi: https://doi.org/10.1161/CIRCHEARTFAILURE.120.007962
Anderson T, Cascino TM, Koelling TM, Perry D, Grafton G, Houston DK, Upadhya B, Kitzman DW, Hummel SL. Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2021 Aug;14(8):e007962. doi: 10.1161/CIRCHEARTFAILURE.120.007962. Epub 2021 Aug 04. PMID: 34344169; PMCID: PMC8373809.
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Chronotropy: the Cinderella of heart failure pathophysiology and management.

JACC. Heart failure

Brubaker PH, Kitzman DW.
PMID: 24621879
JACC Heart Fail. 2013 Jun;1(3):267-9. doi: 10.1016/j.jchf.2013.03.009. Epub 2013 Jun 03.

No abstract available.

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Brubaker PH, Kitzman DW. Chronotropy: the Cinderella of heart failure pathophysiology and management. JACC Heart Fail. 2013;1(3):267-9doi: 10.1016/j.jchf.2013.03.009.
Brubaker, P. H., & Kitzman, D. W. (2013). Chronotropy: the Cinderella of heart failure pathophysiology and management. JACC. Heart failure, 1(3), 267-9. https://doi.org/10.1016/j.jchf.2013.03.009
Brubaker, Peter H, and Kitzman, Dalane W. "Chronotropy: the Cinderella of heart failure pathophysiology and management." JACC. Heart failure vol. 1,3 (2013): 267-9. doi: https://doi.org/10.1016/j.jchf.2013.03.009
Brubaker PH, Kitzman DW. Chronotropy: the Cinderella of heart failure pathophysiology and management. JACC Heart Fail. 2013 Jun;1(3):267-9. doi: 10.1016/j.jchf.2013.03.009. Epub 2013 Jun 03. PMID: 24621879; PMCID: PMC4282140.
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Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial.

The journals of gerontology. Series A, Biological sciences and medical sciences

Espeland MA, Dutton GR, Neiberg RH, Carmichael O, Hayden KM, Johnson KC, Jeffery RW, Baker LD, Cook DR, Kitzman DW, Rapp SR.
PMID: 29846553
J Gerontol A Biol Sci Med Sci. 2018 Oct 08;73(11):1560-1567. doi: 10.1093/gerona/gly124.

BACKGROUND: Lifestyle interventions to reduce weight and increase activity may preserve higher-order cognitive abilities in overweight/obese adults with type 2 diabetes (T2D).METHODS: Adults (N = 5,084) with T2D who enrolled in a randomized clinical trial of a 10-year intensive...

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Espeland MA, Dutton GR, Neiberg RH, et al. Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial. J Gerontol A Biol Sci Med Sci. 2018;73(11):1560-1567doi: 10.1093/gerona/gly124.
Espeland, M. A., Dutton, G. R., Neiberg, R. H., Carmichael, O., Hayden, K. M., Johnson, K. C., Jeffery, R. W., Baker, L. D., Cook, D. R., Kitzman, D. W., Rapp, S. R. (2018). Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial. The journals of gerontology. Series A, Biological sciences and medical sciences, 73(11), 1560-1567. https://doi.org/10.1093/gerona/gly124
Espeland, Mark A, et al. "Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial." The journals of gerontology. Series A, Biological sciences and medical sciences vol. 73,11 (2018): 1560-1567. doi: https://doi.org/10.1093/gerona/gly124
Espeland MA, Dutton GR, Neiberg RH, Carmichael O, Hayden KM, Johnson KC, Jeffery RW, Baker LD, Cook DR, Kitzman DW, Rapp SR. Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial. J Gerontol A Biol Sci Med Sci. 2018 Oct 08;73(11):1560-1567. doi: 10.1093/gerona/gly124. PMID: 29846553; PMCID: PMC6175017.
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Female Heart Health: Is GPER the Missing Link?.

Frontiers in endocrinology

Groban L, Tran QK, Ferrario CM, Sun X, Cheng CP, Kitzman DW, Wang H, Lindsey SH.
PMID: 31993020
Front Endocrinol (Lausanne). 2020 Jan 14;10:919. doi: 10.3389/fendo.2019.00919. eCollection 2019.

The G Protein-Coupled Estrogen Receptor (GPER) is a novel membrane-bound receptor that mediates non-genomic actions of the primary female sex hormone 17β-estradiol. Studies over the past two decades have elucidated the beneficial actions of this receptor in a number...

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Groban L, Tran QK, Ferrario CM, et al. Female Heart Health: Is GPER the Missing Link?. Front Endocrinol (Lausanne). 2020;10:919doi: 10.3389/fendo.2019.00919.
Groban, L., Tran, Q. K., Ferrario, C. M., Sun, X., Cheng, C. P., Kitzman, D. W., Wang, H., & Lindsey, S. H. (2019). Female Heart Health: Is GPER the Missing Link?. Frontiers in endocrinology, 10919. https://doi.org/10.3389/fendo.2019.00919
Groban, Leanne, et al. "Female Heart Health: Is GPER the Missing Link?." Frontiers in endocrinology vol. 10 (2019): 919. doi: https://doi.org/10.3389/fendo.2019.00919
Groban L, Tran QK, Ferrario CM, Sun X, Cheng CP, Kitzman DW, Wang H, Lindsey SH. Female Heart Health: Is GPER the Missing Link?. Front Endocrinol (Lausanne). 2020 Jan 14;10:919. doi: 10.3389/fendo.2019.00919. eCollection 2019. PMID: 31993020; PMCID: PMC6970950.
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Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEART.

Hypertension (Dallas, Tex. : 1979)

Upadhya B, Rocco MV, Pajewski NM, Morgan T, Blackshear J, Hundley WG, Oparil S, Soliman EZ, Cohen DL, Hamilton CA, Cho ME, Kostis WJ, Papademetriou V, Rodriguez CJ, Raj DS, Townsend R, Vasu S, Zamanian S, Kitzman DW.
PMID: 31256724
Hypertension. 2019 Jul 01;HYPERTENSIONAHA11913073. doi: 10.1161/HYPERTENSIONAHA.119.13073. Epub 2019 Jul 01.

In observational studies, left ventricular mass (LVM) and structure are strong predictors of mortality and cardiovascular events. However, the effect of hypertension treatment on LVM reduction and its relation to subsequent outcomes is unclear, particularly at lower blood pressure...

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Upadhya B, Rocco MV, Pajewski NM, et al. Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEART. Hypertension. 2019;HYPERTENSIONAHA11913073doi: 10.1161/HYPERTENSIONAHA.119.13073.
Upadhya, B., Rocco, M. V., Pajewski, N. M., Morgan, T., Blackshear, J., Hundley, W. G., Oparil, S., Soliman, E. Z., Cohen, D. L., Hamilton, C. A., Cho, M. E., Kostis, W. J., Papademetriou, V., Rodriguez, C. J., Raj, D. S., Townsend, R., Vasu, S., Zamanian, S., Kitzman, D. W. (2019). Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEART. Hypertension (Dallas, Tex. : 1979), HYPERTENSIONAHA11913073. https://doi.org/10.1161/HYPERTENSIONAHA.119.13073
Upadhya, Bharathi, et al. "Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEART." Hypertension (Dallas, Tex. : 1979) vol. (2019): HYPERTENSIONAHA11913073. doi: https://doi.org/10.1161/HYPERTENSIONAHA.119.13073
Upadhya B, Rocco MV, Pajewski NM, Morgan T, Blackshear J, Hundley WG, Oparil S, Soliman EZ, Cohen DL, Hamilton CA, Cho ME, Kostis WJ, Papademetriou V, Rodriguez CJ, Raj DS, Townsend R, Vasu S, Zamanian S, Kitzman DW. Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEART. Hypertension. 2019 Jul 01;HYPERTENSIONAHA11913073. doi: 10.1161/HYPERTENSIONAHA.119.13073. Epub 2019 Jul 01. PMID: 31256724; PMCID: PMC7098010.
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Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART.

Hypertension (Dallas, Tex. : 1979)

Upadhya B, Pajewski NM, Rocco MV, Hundley WG, Aurigemma G, Hamilton CA, Bates JT, He J, Chen J, Chonchol M, Glasser SP, Hung AM, Pisoni R, Punzi H, Supiano MA, Toto R, Taylor A, Kitzman DW.
PMID: 33775127
Hypertension. 2021 May 05;77(5):1571-1580. doi: 10.1161/HYPERTENSIONAHA.120.16676. Epub 2021 Mar 29.

[Figure: see text].

Cite
Upadhya B, Pajewski NM, Rocco MV, et al. Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. Hypertension. 2021;77(5):1571-1580doi: 10.1161/HYPERTENSIONAHA.120.16676.
Upadhya, B., Pajewski, N. M., Rocco, M. V., Hundley, W. G., Aurigemma, G., Hamilton, C. A., Bates, J. T., He, J., Chen, J., Chonchol, M., Glasser, S. P., Hung, A. M., Pisoni, R., Punzi, H., Supiano, M. A., Toto, R., Taylor, A., Kitzman, D. W. (2021). Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. Hypertension (Dallas, Tex. : 1979), 77(5), 1571-1580. https://doi.org/10.1161/HYPERTENSIONAHA.120.16676
Upadhya, Bharathi, et al. "Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART." Hypertension (Dallas, Tex. : 1979) vol. 77,5 (2021): 1571-1580. doi: https://doi.org/10.1161/HYPERTENSIONAHA.120.16676
Upadhya B, Pajewski NM, Rocco MV, Hundley WG, Aurigemma G, Hamilton CA, Bates JT, He J, Chen J, Chonchol M, Glasser SP, Hung AM, Pisoni R, Punzi H, Supiano MA, Toto R, Taylor A, Kitzman DW. Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. Hypertension. 2021 May 05;77(5):1571-1580. doi: 10.1161/HYPERTENSIONAHA.120.16676. Epub 2021 Mar 29. PMID: 33775127; PMCID: PMC8035296.
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Incidence and Outcomes of Acute Heart Failure With Preserved Versus Reduced Ejection Fraction in SPRINT.

Circulation. Heart failure

Upadhya B, Willard JJ, Lovato LC, Rocco MV, Lewis CE, Oparil S, Cushman WC, Bates JT, Bello NA, Aurigemma G, Johnson KC, Rodriguez CJ, Raj DS, Rastogi A, Tamariz L, Wiggers A, Kitzman DW.
PMID: 34823375
Circ Heart Fail. 2021 Dec;14(12):e008322. doi: 10.1161/CIRCHEARTFAILURE.121.008322. Epub 2021 Nov 26.

BACKGROUND: In the SPRINT (Systolic Blood Pressure Intervention Trial), intensive BP treatment reduced acute decompensated heart failure (ADHF) events. Here, we report the effect on HF with preserved ejection fraction (HFpEF) and HF with reduced EF (HFrEF) and their...

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Upadhya B, Willard JJ, Lovato LC, et al. Incidence and Outcomes of Acute Heart Failure With Preserved Versus Reduced Ejection Fraction in SPRINT. Circ Heart Fail. 2021;14(12):e008322doi: 10.1161/CIRCHEARTFAILURE.121.008322.
Upadhya, B., Willard, J. J., Lovato, L. C., Rocco, M. V., Lewis, C. E., Oparil, S., Cushman, W. C., Bates, J. T., Bello, N. A., Aurigemma, G., Johnson, K. C., Rodriguez, C. J., Raj, D. S., Rastogi, A., Tamariz, L., Wiggers, A., Kitzman, D. W. (2021). Incidence and Outcomes of Acute Heart Failure With Preserved Versus Reduced Ejection Fraction in SPRINT. Circulation. Heart failure, 14(12), e008322. https://doi.org/10.1161/CIRCHEARTFAILURE.121.008322
Upadhya, Bharathi, et al. "Incidence and Outcomes of Acute Heart Failure With Preserved Versus Reduced Ejection Fraction in SPRINT." Circulation. Heart failure vol. 14,12 (2021): e008322. doi: https://doi.org/10.1161/CIRCHEARTFAILURE.121.008322
Upadhya B, Willard JJ, Lovato LC, Rocco MV, Lewis CE, Oparil S, Cushman WC, Bates JT, Bello NA, Aurigemma G, Johnson KC, Rodriguez CJ, Raj DS, Rastogi A, Tamariz L, Wiggers A, Kitzman DW. Incidence and Outcomes of Acute Heart Failure With Preserved Versus Reduced Ejection Fraction in SPRINT. Circ Heart Fail. 2021 Dec;14(12):e008322. doi: 10.1161/CIRCHEARTFAILURE.121.008322. Epub 2021 Nov 26. PMID: 34823375; PMCID: PMC8692397.
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