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Optimal multiple testing under a Gaussian prior on the effect sizes.

Biometrika

Dobriban E, Fortney K, Kim SK, Owen AB.
PMID: 27046938
Biometrika. 2015 Dec;102(4):753-766. doi: 10.1093/biomet/asv050. Epub 2015 Nov 04.

We develop a new method for large-scale frequentist multiple testing with Bayesian prior information. We find optimal [Formula: see text]-value weights that maximize the average power of the weighted Bonferroni method. Due to the nonconvexity of the optimization problem,...

New insights into old worm proteomes.

Worm

Zimmerman SM, Kim SK.
PMID: 27695651
Worm. 2016 May 04;5(3):e1184391. doi: 10.1080/21624054.2016.1184391. eCollection 2016.

Aging is accompanied by large-scale changes in the proteome, which could have important consequences for cellular and organismal physiology. In this commentary, we review recent studies characterizing the aging proteome in

Showing 1 to 2 of 2 entries