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Investigation of c9orf72 in 4 neurodegenerative disorders.

Archives of neurology

Xi Z, Zinman L, Grinberg Y, Moreno D, Sato C, Bilbao JM, Ghani M, Hernández I, Ruiz A, Boada M, Morón FJ, Lang AE, Marras C, Bruni A, Colao R, Maletta RG, Puccio G, Rainero I, Pinessi L, Galimberti D, Morrison KE, Moorby C, Stockton JD, Masellis M, Black SE, Hazrati LN, Liang Y, van Haersma de With J, Fornazzari L, Villagra R, Rojas-Garcia R, Clarimón J, Mayeux R, Robertson J, St George-Hyslop P, Rogaeva E.
PMID: 22964832
Arch Neurol. 2012 Dec;69(12):1583-90. doi: 10.1001/archneurol.2012.2016.

OBJECTIVE To estimate the allele frequency of C9orf72 (G4C2) repeats in amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), Alzheimer disease (AD), and Parkinson disease (PD). DESIGN The number of repeats was estimated by a 2-step genotyping strategy. For...

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Xi Z, Zinman L, Grinberg Y, et al. Investigation of c9orf72 in 4 neurodegenerative disorders. Arch Neurol. 2012;69(12):1583-90doi: 10.1001/archneurol.2012.2016.
Xi, Z., Zinman, L., Grinberg, Y., Moreno, D., Sato, C., Bilbao, J. M., Ghani, M., Hernández, I., Ruiz, A., Boada, M., Morón, F. J., Lang, A. E., Marras, C., Bruni, A., Colao, R., Maletta, R. G., Puccio, G., Rainero, I., Pinessi, L., Galimberti, D., Morrison, K. E., Moorby, C., Stockton, J. D., Masellis, M., Black, S. E., Hazrati, L. N., Liang, Y., van Haersma de With, J., Fornazzari, L., Villagra, R., Rojas-Garcia, R., Clarimón, J., Mayeux, R., Robertson, J., St George-Hyslop, P., & Rogaeva, E. (2012). Investigation of c9orf72 in 4 neurodegenerative disorders. Archives of neurology, 69(12), 1583-90. https://doi.org/10.1001/archneurol.2012.2016
Xi, Zhengrui, et al. "Investigation of c9orf72 in 4 neurodegenerative disorders." Archives of neurology vol. 69,12 (2012): 1583-90. doi: https://doi.org/10.1001/archneurol.2012.2016
Xi Z, Zinman L, Grinberg Y, Moreno D, Sato C, Bilbao JM, Ghani M, Hernández I, Ruiz A, Boada M, Morón FJ, Lang AE, Marras C, Bruni A, Colao R, Maletta RG, Puccio G, Rainero I, Pinessi L, Galimberti D, Morrison KE, Moorby C, Stockton JD, Masellis M, Black SE, Hazrati LN, Liang Y, van Haersma de With J, Fornazzari L, Villagra R, Rojas-Garcia R, Clarimón J, Mayeux R, Robertson J, St George-Hyslop P, Rogaeva E. Investigation of c9orf72 in 4 neurodegenerative disorders. Arch Neurol. 2012 Dec;69(12):1583-90. doi: 10.1001/archneurol.2012.2016. PMID: 22964832; PMCID: PMC4005900.
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Reproducibility of serum cytokines in an elderly population.

Immunity & ageing : I & A

Guo J, Schupf N, Mayeux RP, Gu Y.
PMID: 33072162
Immun Ageing. 2020 Oct 13;17:29. doi: 10.1186/s12979-020-00201-0. eCollection 2020.

BACKGROUND: It is important to assess the temporal reproducibility of circulating cytokines for their utility in epidemiological studies. However, existing evidence is limited and inconsistent, especially for the elderly population.METHODS: Sixty-five elderly (mean age = 77.89 ± 6.14 years)...

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Guo J, Schupf N, Mayeux RP, et al. Reproducibility of serum cytokines in an elderly population. Immun Ageing. 2020;17:29doi: 10.1186/s12979-020-00201-0.
Guo, J., Schupf, N., Mayeux, R. P., & Gu, Y. (2020). Reproducibility of serum cytokines in an elderly population. Immunity & ageing : I & A, 1729. https://doi.org/10.1186/s12979-020-00201-0
Guo, Jing, et al. "Reproducibility of serum cytokines in an elderly population." Immunity & ageing : I & A vol. 17 (2020): 29. doi: https://doi.org/10.1186/s12979-020-00201-0
Guo J, Schupf N, Mayeux RP, Gu Y. Reproducibility of serum cytokines in an elderly population. Immun Ageing. 2020 Oct 13;17:29. doi: 10.1186/s12979-020-00201-0. eCollection 2020. PMID: 33072162; PMCID: PMC7556943.
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Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y.
PMID: 33938146
Alzheimers Dement. 2021 Dec;17(12):1905-1913. doi: 10.1002/alz.12359. Epub 2021 May 02.

INTRODUCTION: There is limited and inconsistent reporting on the association between Life's Simple 7 (LS7) and dementia in the elderly population.METHODS: Based on the Washington Heights-Inwood Columbia Aging Project (WHICAP), LS7 scores were estimated to assess cardiovascular health status....

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Guo J, Brickman AM, Manly JJ, et al. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021;17(12):1905-1913doi: 10.1002/alz.12359.
Guo, J., Brickman, A. M., Manly, J. J., Reitz, C., Schupf, N., Mayeux, R. P., & Gu, Y. (2021). Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimer's & dementia : the journal of the Alzheimer's Association, 17(12), 1905-1913. https://doi.org/10.1002/alz.12359
Guo, Jing, et al. "Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 17,12 (2021): 1905-1913. doi: https://doi.org/10.1002/alz.12359
Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021 Dec;17(12):1905-1913. doi: 10.1002/alz.12359. Epub 2021 May 02. PMID: 33938146; PMCID: PMC8560654.
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Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y.
PMID: 33938146
Alzheimers Dement. 2021 Dec;17(12):1905-1913. doi: 10.1002/alz.12359. Epub 2021 May 02.

INTRODUCTION: There is limited and inconsistent reporting on the association between Life's Simple 7 (LS7) and dementia in the elderly population.METHODS: Based on the Washington Heights-Inwood Columbia Aging Project (WHICAP), LS7 scores were estimated to assess cardiovascular health status....

Cite
Guo J, Brickman AM, Manly JJ, et al. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021;17(12):1905-1913doi: 10.1002/alz.12359.
Guo, J., Brickman, A. M., Manly, J. J., Reitz, C., Schupf, N., Mayeux, R. P., & Gu, Y. (2021). Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimer's & dementia : the journal of the Alzheimer's Association, 17(12), 1905-1913. https://doi.org/10.1002/alz.12359
Guo, Jing, et al. "Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 17,12 (2021): 1905-1913. doi: https://doi.org/10.1002/alz.12359
Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021 Dec;17(12):1905-1913. doi: 10.1002/alz.12359. Epub 2021 May 02. PMID: 33938146; PMCID: PMC8560654.
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Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities.

Neurology. Genetics

Beecham A, Dong C, Wright CB, Dueker N, Brickman AM, Wang L, DeCarli C, Blanton SH, Rundek T, Mayeux R, Sacco RL.
PMID: 28975155
Neurol Genet. 2017 Sep 25;3(5):e185. doi: 10.1212/NXG.0000000000000185. eCollection 2017 Oct.

OBJECTIVE: To investigate genetic variants influencing white matter hyperintensities (WMHs) in the understudied Hispanic population.METHODS: Using 6.8 million single nucleotide polymorphisms (SNPs), we conducted a genome-wide association study (GWAS) to identify SNPs associated with WMH volume (WMHV) in 922...

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Beecham A, Dong C, Wright CB, et al. Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities. Neurol Genet. 2017;3(5):e185doi: 10.1212/NXG.0000000000000185.
Beecham, A., Dong, C., Wright, C. B., Dueker, N., Brickman, A. M., Wang, L., DeCarli, C., Blanton, S. H., Rundek, T., Mayeux, R., & Sacco, R. L. (2017). Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities. Neurology. Genetics, 3(5), e185. https://doi.org/10.1212/NXG.0000000000000185
Beecham, Ashley, et al. "Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities." Neurology. Genetics vol. 3,5 (2017): e185. doi: https://doi.org/10.1212/NXG.0000000000000185
Beecham A, Dong C, Wright CB, Dueker N, Brickman AM, Wang L, DeCarli C, Blanton SH, Rundek T, Mayeux R, Sacco RL. Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities. Neurol Genet. 2017 Sep 25;3(5):e185. doi: 10.1212/NXG.0000000000000185. eCollection 2017 Oct. PMID: 28975155; PMCID: PMC5619914.
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Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y.
PMID: 33938146
Alzheimers Dement. 2021 May 02; doi: 10.1002/alz.12359. Epub 2021 May 02.

INTRODUCTION: There is limited and inconsistent reporting on the association between Life's Simple 7 (LS7) and dementia in the elderly population.METHODS: Based on the Washington Heights-Inwood Columbia Aging Project (WHICAP), LS7 scores were estimated to assess cardiovascular health status....

Cite
Guo J, Brickman AM, Manly JJ, et al. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021;doi: 10.1002/alz.12359.
Guo, J., Brickman, A. M., Manly, J. J., Reitz, C., Schupf, N., Mayeux, R. P., & Gu, Y. (2021). Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimer's & dementia : the journal of the Alzheimer's Association, . https://doi.org/10.1002/alz.12359
Guo, Jing, et al. "Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. (2021). doi: https://doi.org/10.1002/alz.12359
Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021 May 02; doi: 10.1002/alz.12359. Epub 2021 May 02. PMID: 33938146; PMCID: PMC8560654.
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Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y.
PMID: 33938146
Alzheimers Dement. 2021 Dec;17(12):1905-1913. doi: 10.1002/alz.12359. Epub 2021 May 02.

INTRODUCTION: There is limited and inconsistent reporting on the association between Life's Simple 7 (LS7) and dementia in the elderly population.METHODS: Based on the Washington Heights-Inwood Columbia Aging Project (WHICAP), LS7 scores were estimated to assess cardiovascular health status....

Cite
Guo J, Brickman AM, Manly JJ, et al. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021;17(12):1905-1913doi: 10.1002/alz.12359.
Guo, J., Brickman, A. M., Manly, J. J., Reitz, C., Schupf, N., Mayeux, R. P., & Gu, Y. (2021). Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimer's & dementia : the journal of the Alzheimer's Association, 17(12), 1905-1913. https://doi.org/10.1002/alz.12359
Guo, Jing, et al. "Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 17,12 (2021): 1905-1913. doi: https://doi.org/10.1002/alz.12359
Guo J, Brickman AM, Manly JJ, Reitz C, Schupf N, Mayeux RP, Gu Y. Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimers Dement. 2021 Dec;17(12):1905-1913. doi: 10.1002/alz.12359. Epub 2021 May 02. PMID: 33938146; PMCID: PMC8560654.
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Patterns of tau pathology identified with .

Alzheimer's & dementia : the journal of the Alzheimer's Association

Kreisl WC, Lao PJ, Johnson A, Tomljanovic Z, Klein J, Polly K, Maas B, Laing KK, Chesebro AG, Igwe K, Razlighi QR, Honig LS, Yan X, Lee S, Mintz A, Luchsinger JA, Stern Y, Devanand DP, Brickman AM.
PMID: 34057284
Alzheimers Dement. 2021 May 31; doi: 10.1002/alz.12384. Epub 2021 May 31.

No abstract available.

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Kreisl WC, Lao PJ, Johnson A, et al. Patterns of tau pathology identified with . Alzheimers Dement. 2021;doi: 10.1002/alz.12384.
Kreisl, W. C., Lao, P. J., Johnson, A., Tomljanovic, Z., Klein, J., Polly, K., Maas, B., Laing, K. K., Chesebro, A. G., Igwe, K., Razlighi, Q. R., Honig, L. S., Yan, X., Lee, S., Mintz, A., Luchsinger, J. A., Stern, Y., Devanand, D. P., & Brickman, A. M. (2021). Patterns of tau pathology identified with . Alzheimer's & dementia : the journal of the Alzheimer's Association, . https://doi.org/10.1002/alz.12384
Kreisl, William Charles, et al. "Patterns of tau pathology identified with ." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. (2021). doi: https://doi.org/10.1002/alz.12384
Kreisl WC, Lao PJ, Johnson A, Tomljanovic Z, Klein J, Polly K, Maas B, Laing KK, Chesebro AG, Igwe K, Razlighi QR, Honig LS, Yan X, Lee S, Mintz A, Luchsinger JA, Stern Y, Devanand DP, Brickman AM. Patterns of tau pathology identified with . Alzheimers Dement. 2021 May 31; doi: 10.1002/alz.12384. Epub 2021 May 31. PMID: 34057284; PMCID: PMC8630090.
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Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population.

Neurology

Angevaare MJ, Vonk JMJ, Bertola L, Zahodne L, Watson CW, Boehme A, Schupf N, Mayeux R, Geerlings MI, Manly JJ.
PMID: 34853178
Neurology. 2022 Jan 04;98(1):e15-e26. doi: 10.1212/WNL.0000000000013017. Epub 2021 Dec 01.

BACKGROUND AND OBJECTIVES: To investigate sociodemographic and medical predictors of incident mild cognitive impairment (MCI) and subsequent course of MCI at follow-up, including sustained MCI diagnosis, classification as cognitively normal, and progression to dementia.METHODS: Within a community-based cohort, diagnoses...

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Angevaare MJ, Vonk JMJ, Bertola L, et al. Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population. Neurology. 2021;98(1):e15-e26doi: 10.1212/WNL.0000000000013017.
Angevaare, M. J., Vonk, J. M. J., Bertola, L., Zahodne, L., Watson, C. W., Boehme, A., Schupf, N., Mayeux, R., Geerlings, M. I., & Manly, J. J. (2022). Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population. Neurology, 98(1), e15-e26. https://doi.org/10.1212/WNL.0000000000013017
Angevaare, Milou J, et al. "Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population." Neurology vol. 98,1 (2022): e15-e26. doi: https://doi.org/10.1212/WNL.0000000000013017
Angevaare MJ, Vonk JMJ, Bertola L, Zahodne L, Watson CW, Boehme A, Schupf N, Mayeux R, Geerlings MI, Manly JJ. Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population. Neurology. 2022 Jan 04;98(1):e15-e26. doi: 10.1212/WNL.0000000000013017. Epub 2021 Dec 01. PMID: 34853178; PMCID: PMC8726570.
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Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population.

Neurology

Angevaare MJ, Vonk JMJ, Bertola L, Zahodne L, Watson CW, Boehme A, Schupf N, Mayeux R, Geerlings MI, Manly JJ.
PMID: 34853178
Neurology. 2022 Jan 04;98(1):e15-e26. doi: 10.1212/WNL.0000000000013017. Epub 2021 Dec 01.

BACKGROUND AND OBJECTIVES: To investigate sociodemographic and medical predictors of incident mild cognitive impairment (MCI) and subsequent course of MCI at follow-up, including sustained MCI diagnosis, classification as cognitively normal, and progression to dementia.METHODS: Within a community-based cohort, diagnoses...

Cite
Angevaare MJ, Vonk JMJ, Bertola L, et al. Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population. Neurology. 2021;98(1):e15-e26doi: 10.1212/WNL.0000000000013017.
Angevaare, M. J., Vonk, J. M. J., Bertola, L., Zahodne, L., Watson, C. W., Boehme, A., Schupf, N., Mayeux, R., Geerlings, M. I., & Manly, J. J. (2022). Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population. Neurology, 98(1), e15-e26. https://doi.org/10.1212/WNL.0000000000013017
Angevaare, Milou J, et al. "Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population." Neurology vol. 98,1 (2022): e15-e26. doi: https://doi.org/10.1212/WNL.0000000000013017
Angevaare MJ, Vonk JMJ, Bertola L, Zahodne L, Watson CW, Boehme A, Schupf N, Mayeux R, Geerlings MI, Manly JJ. Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population. Neurology. 2022 Jan 04;98(1):e15-e26. doi: 10.1212/WNL.0000000000013017. Epub 2021 Dec 01. PMID: 34853178; PMCID: PMC8726570.
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Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population.

Current Alzheimer research

Nishikawa M, Brickman AM, Manly JJ, Schupf N, Mayeux RP, Gu Y.
PMID: 34951365
Curr Alzheimer Res. 2021;18(12):984-992. doi: 10.2174/1567205019666211222115142.

OBJECTIVE: This study aimed to investigate the association between dietary prebiotic intake and risk for Alzheimer's disease (AD).METHODS: This longitudinal study includes 1,837 elderly (≥65 years) participants of a multi-ethnic community-based cohort study who were dementia-free at baseline and...

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Nishikawa M, Brickman AM, Manly JJ, et al. Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population. Curr Alzheimer Res. 2021;18(12):984-992doi: 10.2174/1567205019666211222115142.
Nishikawa, M., Brickman, A. M., Manly, J. J., Schupf, N., Mayeux, R. P., & Gu, Y. (2021). Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population. Current Alzheimer research, 18(12), 984-992. https://doi.org/10.2174/1567205019666211222115142
Nishikawa, Mia, et al. "Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population." Current Alzheimer research vol. 18,12 (2021): 984-992. doi: https://doi.org/10.2174/1567205019666211222115142
Nishikawa M, Brickman AM, Manly JJ, Schupf N, Mayeux RP, Gu Y. Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population. Curr Alzheimer Res. 2021;18(12):984-992. doi: 10.2174/1567205019666211222115142. PMID: 34951365.
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Daytime Sleepiness and Sleep Inadequacy as Risk Factors for Dementia.

Dementia and geriatric cognitive disorders extra

Tsapanou A, Gu Y, Manly J, Schupf N, Tang MX, Zimmerman M, Scarmeas N, Stern Y.
PMID: 26273244
Dement Geriatr Cogn Dis Extra. 2015 Jul 10;5(2):286-95. doi: 10.1159/000431311. eCollection 2015.

BACKGROUND/AIMS: To examine the association between self-reported sleep problems and incidence of dementia in community-dwelling elderly people.METHODS: 1,041 nondemented participants over 65 years old were examined longitudinally. Sleep problems were estimated using the RAND Medical Outcomes Study Sleep Scale...

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Tsapanou A, Gu Y, Manly J, et al. Daytime Sleepiness and Sleep Inadequacy as Risk Factors for Dementia. Dement Geriatr Cogn Dis Extra. 2015;5(2):286-95doi: 10.1159/000431311.
Tsapanou, A., Gu, Y., Manly, J., Schupf, N., Tang, M. X., Zimmerman, M., Scarmeas, N., & Stern, Y. (2015). Daytime Sleepiness and Sleep Inadequacy as Risk Factors for Dementia. Dementia and geriatric cognitive disorders extra, 5(2), 286-95. https://doi.org/10.1159/000431311
Tsapanou, Angeliki, et al. "Daytime Sleepiness and Sleep Inadequacy as Risk Factors for Dementia." Dementia and geriatric cognitive disorders extra vol. 5,2 (2015): 286-95. doi: https://doi.org/10.1159/000431311
Tsapanou A, Gu Y, Manly J, Schupf N, Tang MX, Zimmerman M, Scarmeas N, Stern Y. Daytime Sleepiness and Sleep Inadequacy as Risk Factors for Dementia. Dement Geriatr Cogn Dis Extra. 2015 Jul 10;5(2):286-95. doi: 10.1159/000431311. eCollection 2015. PMID: 26273244; PMCID: PMC4521063.
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