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Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction.

F1000Research

Stoeckel LE, Arvanitakis Z, Gandy S, Small D, Kahn CR, Pascual-Leone A, Pawlyk A, Sherwin R, Smith P.
PMID: 27303627
F1000Res. 2016 Mar 15;5:353. doi: 10.12688/f1000research.8300.2. eCollection 2016.

Scientific evidence has established several links between metabolic and neurocognitive dysfunction, and epidemiologic evidence has revealed an increased risk of Alzheimer's disease and vascular dementia in patients with diabetes. In July 2015, the National Institute of Diabetes, Digestive, and...

Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons.

Frontiers in aging neuroscience

Fleischman DA, Yu L, Arfanakis K, Han SD, Barnes LL, Arvanitakis Z, Boyle PA, Bennett DA.
PMID: 23760360
Front Aging Neurosci. 2013 Jun 05;5:21. doi: 10.3389/fnagi.2013.00021. eCollection 2013.

Early identification of persons at risk for cognitive decline in aging is critical to optimizing treatment to delay or avoid a clinical diagnosis of mild cognitive impairment (MCI) or dementia due to Alzheimer's disease (AD). To accomplish early identification,...

White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age.

Annals of clinical and translational neurology

Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA.
PMID: 27752514
Ann Clin Transl Neurol. 2016 Sep 01;3(10):791-800. doi: 10.1002/acn3.343. eCollection 2016 Oct.

OBJECTIVE: Examine the association of white matter hyperintensities (WMH) with risk of incident mild cognitive impairment (MCI) and rate of decline in multiple cognitive systems in community-based older persons.METHODS: Participants (RESULTS: During up to about 6 years of follow-up...

Showing 1 to 3 of 3 entries