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Showing 1 to 12 of 19 entries
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A Gordian knot: disentangling comorbidities in heart failure.

European journal of heart failure

Luo N, Mentz RJ.
PMID: 27373232
Eur J Heart Fail. 2016 Jul;18(7):759-61. doi: 10.1002/ejhf.570. Epub 2016 Jul 04.

No abstract available.

Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle.

JCI insight

Zhang H, Bryson VG, Wang C, Li T, Kerr JP, Wilson R, Muoio DM, Bloch RJ, Ward C, Rosenberg PB.
PMID: 34494555
JCI Insight. 2021 Sep 08;6(17). doi: 10.1172/jci.insight.143472.

Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility. STIM1 occupies space in the junctional SR membrane of the...

Physical Rehabilitation in Older Patients Hospitalized with Acute Heart Failure and Diabetes: Insights from REHAB-HF.

The American journal of medicine

Murray EM, Whellan DJ, Chen H, Bertoni AG, Duncan P, Pastva AM, Kitzman DW, Mentz RJ.
PMID: 34516959
Am J Med. 2022 Jan;135(1):82-90. doi: 10.1016/j.amjmed.2021.08.001. Epub 2021 Sep 10.

BACKGROUND: Prior studies showed an attenuated response to exercise training among patients with heart failure and type 2 diabetes mellitus. We explored the interaction between diabetes status and a novel, transitional, tailored, progressive rehabilitation intervention that improved physical function...

Heart Failure Primary Prevention: What Does SPRINT Add?: Recent Advances in Hypertension.

Hypertension (Dallas, Tex. : 1979)

Raby K, Rocco M, Oparil S, Gilbert ON, Upadhya B.
PMID: 33813850
Hypertension. 2021 Jun;77(6):1804-1814. doi: 10.1161/HYPERTENSIONAHA.121.16503. Epub 2021 Apr 05.

Hypertension is the most prevalent modifiable factor for the development of heart failure. However, the optimal blood pressure (BP) target for preventing heart failure remains uncertain. The SPRINT (Systolic BP Intervention Trial) was a large, randomized open-label trial (n=9361...

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review.

Journal of the American College of Cardiology

Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D.
PMID: 34503685
J Am Coll Cardiol. 2021 Sep 14;78(11):1166-1187. doi: 10.1016/j.jacc.2021.07.014.

Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved ejection fraction (HFpEF), the most common form of heart failure among older individuals. The recent recognition that HFpEF is likely a systemic, multiorgan disorder that shares...

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review.

Journal of the American College of Cardiology

Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D.
PMID: 34503685
J Am Coll Cardiol. 2021 Sep 14;78(11):1166-1187. doi: 10.1016/j.jacc.2021.07.014.

Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved ejection fraction (HFpEF), the most common form of heart failure among older individuals. The recent recognition that HFpEF is likely a systemic, multiorgan disorder that shares...

Heart Failure Primary Prevention: What Does SPRINT Add?: Recent Advances in Hypertension.

Hypertension (Dallas, Tex. : 1979)

Raby K, Rocco M, Oparil S, Gilbert ON, Upadhya B.
PMID: 33813850
Hypertension. 2021 Jun;77(6):1804-1814. doi: 10.1161/HYPERTENSIONAHA.121.16503. Epub 2021 Apr 05.

Hypertension is the most prevalent modifiable factor for the development of heart failure. However, the optimal blood pressure (BP) target for preventing heart failure remains uncertain. The SPRINT (Systolic BP Intervention Trial) was a large, randomized open-label trial (n=9361...

Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART.

Hypertension (Dallas, Tex. : 1979)

Upadhya B, Pajewski NM, Rocco MV, Hundley WG, Aurigemma G, Hamilton CA, Bates JT, He J, Chen J, Chonchol M, Glasser SP, Hung AM, Pisoni R, Punzi H, Supiano MA, Toto R, Taylor A, Kitzman DW.
PMID: 33775127
Hypertension. 2021 May 05;77(5):1571-1580. doi: 10.1161/HYPERTENSIONAHA.120.16676. Epub 2021 Mar 29.

[Figure: see text].

Older Patients With Acute Decompensated Heart Failure Who Live Alone: An Analysis From the REHAB-HF Trial.

Journal of cardiac failure

Warraich HJ, Kitzman DW, Nelson MB, Mentz RJ, Rosenberg PB, Lev Y, Whellan DJ.
PMID: 34147611
J Card Fail. 2021 Jun 18; doi: 10.1016/j.cardfail.2021.06.005. Epub 2021 Jun 18.

No abstract available.

Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction.

Circulation. Heart failure

Anderson T, Cascino TM, Koelling TM, Perry D, Grafton G, Houston DK, Upadhya B, Kitzman DW, Hummel SL.
PMID: 34344169
Circ Heart Fail. 2021 Aug;14(8):e007962. doi: 10.1161/CIRCHEARTFAILURE.120.007962. Epub 2021 Aug 04.

BACKGROUND: Obesity is common in heart failure with preserved ejection fraction (HFpEF), and a hypocaloric diet can improve functional capacity. Malnutrition, sarcopenia, and frailty are also frequently present, and calorie restriction could harm some patients. Resting metabolic rate (RMR)...

Chronotropy: the Cinderella of heart failure pathophysiology and management.

JACC. Heart failure

Brubaker PH, Kitzman DW.
PMID: 24621879
JACC Heart Fail. 2013 Jun;1(3):267-9. doi: 10.1016/j.jchf.2013.03.009. Epub 2013 Jun 03.

No abstract available.

Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEART.

Hypertension (Dallas, Tex. : 1979)

Upadhya B, Rocco MV, Pajewski NM, Morgan T, Blackshear J, Hundley WG, Oparil S, Soliman EZ, Cohen DL, Hamilton CA, Cho ME, Kostis WJ, Papademetriou V, Rodriguez CJ, Raj DS, Townsend R, Vasu S, Zamanian S, Kitzman DW.
PMID: 31256724
Hypertension. 2019 Jul 01;HYPERTENSIONAHA11913073. doi: 10.1161/HYPERTENSIONAHA.119.13073. Epub 2019 Jul 01.

In observational studies, left ventricular mass (LVM) and structure are strong predictors of mortality and cardiovascular events. However, the effect of hypertension treatment on LVM reduction and its relation to subsequent outcomes is unclear, particularly at lower blood pressure...

Showing 1 to 12 of 19 entries