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Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

Distinct Prognostic Role of Serum Uric Acid Levels for Predicting All-Cause Mortality Among Chinese Adults Aged 45~75 Years With and Without Diabetes.

Frontiers in endocrinology

Zhu B, Zhang J, Song N, Shi Y, Fang Y, Ding X, Li Y.
PMID: 34867828
Front Endocrinol (Lausanne). 2021 Nov 16;12:782230. doi: 10.3389/fendo.2021.782230. eCollection 2021.

INTRODUCTION: The current study sought to explore the effect of baseline serum uric acid (SUA) on the risk of all-cause mortality among Chinese adults aged 45~75 years and to determine its interaction relationship with diabetes.METHODS: The study was designed...

Does Living with Grandparents Affect Children's and Adolescents' Health? Evidence from China.

International journal of environmental research and public health

Yu J, Zhang Z.
PMID: 34831704
Int J Environ Res Public Health. 2021 Nov 13;18(22). doi: 10.3390/ijerph182211948.

The level of nutritional health of children and adolescents is an important indicator of social development, and grandparents, as common co-caregivers, may have a considerable impact on the health level of their grandchildren. In this paper, we investigated the...

Multi-Trajectories of Macronutrient Intake and Their Associations with Obesity among Chinese Adults from 1991 to 2018: A Prospective Study.

Nutrients

Zhang X, Zhang J, Du W, Su C, Ouyang Y, Huang F, Jia X, Li L, Bai J, Zhang B, Wang Z, Du S, Wang H.
PMID: 35010888
Nutrients. 2021 Dec 21;14(1). doi: 10.3390/nu14010013.

Studies on macronutrient intake and obesity have been inconclusive. This study examined the associations between multi-trajectories of macronutrients and the risk of obesity in China. We used data from 7914 adults who participated in the China Health and Nutrition...

Multi-Trajectories of Macronutrient Intake and Their Associations with Obesity among Chinese Adults from 1991 to 2018: A Prospective Study.

Nutrients

Zhang X, Zhang J, Du W, Su C, Ouyang Y, Huang F, Jia X, Li L, Bai J, Zhang B, Wang Z, Du S, Wang H.
PMID: 35010888
Nutrients. 2021 Dec 21;14(1). doi: 10.3390/nu14010013.

Studies on macronutrient intake and obesity have been inconclusive. This study examined the associations between multi-trajectories of macronutrients and the risk of obesity in China. We used data from 7914 adults who participated in the China Health and Nutrition...

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

A doubly robust method to handle missing multilevel outcome data with application to the China Health and Nutrition Survey.

Statistics in medicine

Butera NM, Zeng D, Green Howard A, Gordon-Larsen P, Cai J.
PMID: 34786739
Stat Med. 2021 Nov 16; doi: 10.1002/sim.9260. Epub 2021 Nov 16.

Missing data are common in longitudinal cohort studies and can lead to bias, particularly in studies with informative missingness. Many common methods for handling informatively missing data in survey samples require correctly specifying a model for missingness. Although doubly...

The nutrition transition to a stage of high obesity and noncommunicable disease prevalence dominated by ultra-processed foods is not inevitable.

Obesity reviews : an official journal of the International Association for the Study of Obesity

Popkin BM, Ng SW.
PMID: 34632692
Obes Rev. 2022 Jan;23(1):e13366. doi: 10.1111/obr.13366. Epub 2021 Oct 10.

The Nutrition Transition model is presented with the nature and pace of change in key stages varying by location and subpopulations. At present, all high-income and many low- and middle-income countries are in a stage of the transition where...

Socioeconomic gradients in the Westernization of diet in China over 20 years.

SSM - population health

Howard AG, Attard SM, Herring AH, Wang H, Du S, Gordon-Larsen P.
PMID: 34703875
SSM Popul Health. 2021 Oct 15;16:100943. doi: 10.1016/j.ssmph.2021.100943. eCollection 2021 Dec.

INTRODUCTION: In low-middle income countries, urbanization leads to changes from traditional to Western diet, which are often accompanied by reductions in cardiometabolic health. Whether socioeconomic status buffers these urbanization-related diet changes over time is unknown.OBJECTIVE: To examine whether the...

Showing 1 to 10 of 10 entries