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Host Kinase Activity is Required for Coxiella burnetii Parasitophorous Vacuole Formation.

Frontiers in microbiology

Hussain SK, Broederdorf LJ, Sharma UM, Voth DE.
PMID: 21772829
Front Microbiol. 2010 Dec 23;1:137. doi: 10.3389/fmicb.2010.00137. eCollection 2010.

Coxiella burnetii is the etiologic agent of human Q fever and targets alveolar phagocytic cells in vivo wherein the pathogen generates a phagolysosome-like parasitophorous vacuole (PV) for replication. C. burnetii displays a prolonged growth cycle, making PV maintenance critical...

ThANKs for the repeat: Intracellular pathogens exploit a common eukaryotic domain.

Cellular logistics

Voth DE.
PMID: 22279611
Cell Logist. 2011 Jul;1(4):128-132. doi: 10.4161/cl.1.4.18738. Epub 2011 Jul 01.

Bacterial pathogens are renowned cell biologists that subvert detrimental host responses by manipulating eukaryotic protein function. A select group of pathogens use a specialized type IV secretion system (T4SS) as a conduit to deliver an arsenal of proteins into...

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