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High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication.

ACS infectious diseases

Edwards MR, Pietzsch C, Vausselin T, Shaw ML, Bukreyev A, Basler CF.
PMID: 26284260
ACS Infect Dis. 2015 Aug 14;1(8):380-7. doi: 10.1021/acsinfecdis.5b00053. Epub 2015 Jun 24.

Ebola virus (EBOV), a member of the family Filoviridae, is a nonsegmented negative-sense RNA virus that causes severe, often lethal, disease in humans. EBOV RNA synthesis is carried out by a complex that includes several viral proteins. The function...

Showing 1 to 1 of 1 entries