Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 6 of 6 entries
Sorted by: Best Match Show Resources per page
Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway.

Genomics data

Green RR, Wilkins C, Pattabhi S, Dong R, Loo Y, Gale M.
PMID: 26981429
Genom Data. 2016 Feb 01;7:290-2. doi: 10.1016/j.gdata.2016.01.020. eCollection 2016 Mar.

The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3). We identified small molecule compounds that activate...

Cite
Green RR, Wilkins C, Pattabhi S, et al. Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway. Genom Data. 2016;7:290-2doi: 10.1016/j.gdata.2016.01.020.
Green, R. R., Wilkins, C., Pattabhi, S., Dong, R., Loo, Y., & Gale, M. (2016). Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway. Genomics data, 7290-2. https://doi.org/10.1016/j.gdata.2016.01.020
Green, R R, et al. "Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway." Genomics data vol. 7 (2016): 290-2. doi: https://doi.org/10.1016/j.gdata.2016.01.020
Green RR, Wilkins C, Pattabhi S, Dong R, Loo Y, Gale M. Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway. Genom Data. 2016 Feb 01;7:290-2. doi: 10.1016/j.gdata.2016.01.020. eCollection 2016 Mar. PMID: 26981429; PMCID: PMC4778670.
Copy Download .nbib Format: NLM
Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model.

Genomics data

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, de Villena FP, Baric R, Heise M, Gale M.
PMID: 27843766
Genom Data. 2016 Oct 14;10:114-117. doi: 10.1016/j.gdata.2016.10.006. eCollection 2016 Dec.

Flaviviruses are hematophagous arthropod-viruses that pose global challenges to human health. Like Zika virus, West Nile Virus (WNV) is a flavivirus for which no approved vaccine exists [1]. The role host genetics play in early detection and response to...

Cite
Green R, Wilkins C, Thomas S, et al. Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model. Genom Data. 2016;10:114-117doi: 10.1016/j.gdata.2016.10.006.
Green, R., Wilkins, C., Thomas, S., Sekine, A., Ireton, R. C., Ferris, M. T., Hendrick, D. M., Voss, K., de Villena, F. P., Baric, R., Heise, M., & Gale, M. (2016). Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model. Genomics data, 10114-117. https://doi.org/10.1016/j.gdata.2016.10.006
Green, Richard, et al. "Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model." Genomics data vol. 10 (2016): 114-117. doi: https://doi.org/10.1016/j.gdata.2016.10.006
Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, de Villena FP, Baric R, Heise M, Gale M. Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model. Genom Data. 2016 Oct 14;10:114-117. doi: 10.1016/j.gdata.2016.10.006. eCollection 2016 Dec. PMID: 27843766; PMCID: PMC5097955.
Copy Download .nbib Format: NLM
Innate cell microenvironments in lymph nodes shape the generation of T cell responses during type I inflammation.

Science immunology

Leal JM, Huang JY, Kohli K, Stoltzfus C, Lyons-Cohen MR, Olin BE, Gale M, Gerner MY.
PMID: 33579750
Sci Immunol. 2021 Feb 12;6(56). doi: 10.1126/sciimmunol.abb9435.

Microanatomical organization of innate immune cells within lymph nodes (LNs) is critical for the generation of adaptive responses. In particular, steady-state LN-resident dendritic cells (Res cDCs) are strategically localized to intercept lymph-draining antigens. Whether myeloid cell organization changes during...

Cite
Leal JM, Huang JY, Kohli K, et al. Innate cell microenvironments in lymph nodes shape the generation of T cell responses during type I inflammation. Sci Immunol. 2021;6(56)doi: 10.1126/sciimmunol.abb9435.
Leal, J. M., Huang, J. Y., Kohli, K., Stoltzfus, C., Lyons-Cohen, M. R., Olin, B. E., Gale, M., & Gerner, M. Y. (2021). Innate cell microenvironments in lymph nodes shape the generation of T cell responses during type I inflammation. Science immunology, 6(56), . https://doi.org/10.1126/sciimmunol.abb9435
Leal, Joseph M, et al. "Innate cell microenvironments in lymph nodes shape the generation of T cell responses during type I inflammation." Science immunology vol. 6,56 (2021). doi: https://doi.org/10.1126/sciimmunol.abb9435
Leal JM, Huang JY, Kohli K, Stoltzfus C, Lyons-Cohen MR, Olin BE, Gale M, Gerner MY. Innate cell microenvironments in lymph nodes shape the generation of T cell responses during type I inflammation. Sci Immunol. 2021 Feb 12;6(56). doi: 10.1126/sciimmunol.abb9435. PMID: 33579750; PMCID: PMC8274717.
Copy Download .nbib Format: NLM
Interferon Lambda Genetics and Biology in Regulation of Viral Control.

Frontiers in immunology

Hemann EA, Gale M, Savan R.
PMID: 29270173
Front Immunol. 2017 Dec 06;8:1707. doi: 10.3389/fimmu.2017.01707. eCollection 2017.

Type III interferons, also known as interferon lambdas (IFNλs), are the most recent addition to the IFN family following their discovery in 2003. Initially, IFNλ was demonstrated to induce expression of interferon-stimulated genes and exert antiviral properties in a...

Cite
Hemann EA, Gale M, Savan R. Interferon Lambda Genetics and Biology in Regulation of Viral Control. Front Immunol. 2017;8:1707doi: 10.3389/fimmu.2017.01707.
Hemann, E. A., Gale, M., & Savan, R. (2017). Interferon Lambda Genetics and Biology in Regulation of Viral Control. Frontiers in immunology, 81707. https://doi.org/10.3389/fimmu.2017.01707
Hemann, Emily A, et al. "Interferon Lambda Genetics and Biology in Regulation of Viral Control." Frontiers in immunology vol. 8 (2017): 1707. doi: https://doi.org/10.3389/fimmu.2017.01707
Hemann EA, Gale M, Savan R. Interferon Lambda Genetics and Biology in Regulation of Viral Control. Front Immunol. 2017 Dec 06;8:1707. doi: 10.3389/fimmu.2017.01707. eCollection 2017. PMID: 29270173; PMCID: PMC5723907.
Copy Download .nbib Format: NLM
Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine.

Nature biomedical engineering

Li J, Baird MA, Davis MA, Tai W, Zweifel LS, Adams Waldorf KM, Gale M, Rajagopal L, Pierce RH, Gao X.
PMID: 29082104
Nat Biomed Eng. 2017;1. doi: 10.1038/s41551-017-0082. Epub 2017 Jun 05.

The ability to detect biomarkers with ultrahigh sensitivity radically transformed biology and disease diagnosis. However, owing to incompatibilities with infrastructure in current biological and medical laboratories, recent innovations in analytical technology have not received broad adoption. Here, we report...

Cite
Li J, Baird MA, Davis MA, et al. Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine. Nat Biomed Eng. 2017;1doi: 10.1038/s41551-017-0082.
Li, J., Baird, M. A., Davis, M. A., Tai, W., Zweifel, L. S., Adams Waldorf, K. M., Gale, M., Rajagopal, L., Pierce, R. H., & Gao, X. (2017). Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine. Nature biomedical engineering, 1. https://doi.org/10.1038/s41551-017-0082
Li, Junwei, et al. "Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine." Nature biomedical engineering vol. 1 (2017). doi: https://doi.org/10.1038/s41551-017-0082
Li J, Baird MA, Davis MA, Tai W, Zweifel LS, Adams Waldorf KM, Gale M, Rajagopal L, Pierce RH, Gao X. Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine. Nat Biomed Eng. 2017;1. doi: 10.1038/s41551-017-0082. Epub 2017 Jun 05. PMID: 29082104; PMCID: PMC5654575.
Copy Download .nbib Format: NLM
Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population.

Genomics data

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, Pardo-Manuel de Villena F, Baric RS, Heise MT, Gale M.
PMID: 27872814
Genom Data. 2016 Oct 14;10:137-140. doi: 10.1016/j.gdata.2016.10.005. eCollection 2016 Dec.

West Nile Virus (WNV) is a mosquito-transmitted virus from the Flaviviridae family that causes fever in 1 in 5 infected people. WNV can also become neuro-invasive and cross the blood-brain barrier leading to severe neurological symptoms in a subset...

Cite
Green R, Wilkins C, Thomas S, et al. Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population. Genom Data. 2016;10:137-140doi: 10.1016/j.gdata.2016.10.005.
Green, R., Wilkins, C., Thomas, S., Sekine, A., Ireton, R. C., Ferris, M. T., Hendrick, D. M., Voss, K., Pardo-Manuel de Villena, F., Baric, R. S., Heise, M. T., & Gale, M. (2016). Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population. Genomics data, 10137-140. https://doi.org/10.1016/j.gdata.2016.10.005
Green, Richard, et al. "Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population." Genomics data vol. 10 (2016): 137-140. doi: https://doi.org/10.1016/j.gdata.2016.10.005
Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, Pardo-Manuel de Villena F, Baric RS, Heise MT, Gale M. Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population. Genom Data. 2016 Oct 14;10:137-140. doi: 10.1016/j.gdata.2016.10.005. eCollection 2016 Dec. PMID: 27872814; PMCID: PMC5107684.
Copy Download .nbib Format: NLM
Showing 1 to 6 of 6 entries