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Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy.

PLoS currents

Larkindale J, Abresch R, Aviles E, Bronson A, Chin J, Furlong P, Gordish-Dressman H, Habeeb-Louks E, Henricson E, Kroger H, Lynn C, Lynn S, Martin D, Nuckolls G, Rooney W, Romero K, Sweeney L, Vandenborne K, Walter G, Wolff J, Wong B, McDonald CM, Duchenne Regulatory Science Consortium Imaging-Dmd Consortium And The Cinrg Investigators MO.
PMID: 28228973
PLoS Curr. 2017 Jan 12;9. doi: 10.1371/currents.md.83071bbd728982f2f1073f4950e03586.

INTRODUCTION: The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration...

Leg muscle MRI in identical twin boys with duchenne muscular dystrophy.

Muscle & nerve

Willcocks RJ, Triplett WT, Lott DJ, Forbes SC, Batra A, Sweeney HL, Mendell JR, Vandenborne K, Walter GA.
PMID: 29365354
Muscle Nerve. 2018 Jan 24; doi: 10.1002/mus.26081. Epub 2018 Jan 24.

No abstract available.

Disease-modifying effects of orally bioavailable NF-.

JCI insight

Hammers DW, Sleeper MM, Forbes SC, Coker CC, Jirousek MR, Zimmer M, Walter GA, Sweeney HL.
PMID: 28018975
JCI Insight. 2016 Dec 22;1(21):e90341. doi: 10.1172/jci.insight.90341.

Duchenne muscular dystrophy (DMD) is a devastating muscle disease characterized by progressive muscle deterioration and replacement with an aberrant fatty, fibrous matrix. Chronic upregulation of nuclear factor κB (NF-κB) is implicated as a driver of the dystrophic pathogenesis. Herein,...

Texture Analysis for Muscular Dystrophy Classification in MRI with Improved Class Activation Mapping.

Pattern recognition

Cai J, Xing F, Batra A, Liu F, Walter GA, Vandenborne K, Yang L.
PMID: 31105339
Pattern Recognit. 2019 Feb;86:368-375. doi: 10.1016/j.patcog.2018.08.012. Epub 2018 Sep 18.

The muscular dystrophies are made up of a diverse group of rare genetic diseases characterized by progressive loss of muscle strength and muscle damage. Since there is no cure for muscular dystrophy and clinical outcome measures are limited, it...

Showing 1 to 4 of 4 entries