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Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study.

International journal of molecular epidemiology and genetics

Pellatt AJ, Wolff RK, Lundgreen A, Cawthon R, Slattery ML.
PMID: 23050049
Int J Mol Epidemiol Genet. 2012;3(3):184-94. Epub 2012 Aug 31.

BACKGROUND: Telomeres cap the ends of chromosomes and help maintain genomic stability and integrity. Telomere length (TL) has been linked to a number of diseases, including a variety of cancers; however, the association between TL and risk for colorectal...

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Pellatt AJ, Wolff RK, Lundgreen A, et al. Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study. Int J Mol Epidemiol Genet. 2012;3(3):184-94
Pellatt, A. J., Wolff, R. K., Lundgreen, A., Cawthon, R., & Slattery, M. L. (2012). Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study. International journal of molecular epidemiology and genetics, 3(3), 184-94.
Pellatt, Andrew J, et al. "Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study." International journal of molecular epidemiology and genetics vol. 3,3 (2012): 184-94.
Pellatt AJ, Wolff RK, Lundgreen A, Cawthon R, Slattery ML. Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study. Int J Mol Epidemiol Genet. 2012;3(3):184-94. Epub 2012 Aug 31. PMID: 23050049; PMCID: PMC3459220.
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Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.

International journal of molecular epidemiology and genetics

Slattery ML, Lundgreen A, Mullany LE, Penney RB, Wolff RK.
PMID: 24959314
Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014.

BACKGROUND: Candidate pathway approaches in disease association studies often utilize a tagSNP approach to capture genetic variation. In this paper we assess gene expression patterns with SNPs in genes in the CHIEF pathway to help determine their potential functionality.METHODS:...

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Slattery ML, Lundgreen A, Mullany LE, et al. Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality. Int J Mol Epidemiol Genet. 2014;5(2):100-11
Slattery, M. L., Lundgreen, A., Mullany, L. E., Penney, R. B., & Wolff, R. K. (2014). Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality. International journal of molecular epidemiology and genetics, 5(2), 100-11.
Slattery, Martha L, et al. "Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality." International journal of molecular epidemiology and genetics vol. 5,2 (2014): 100-11.
Slattery ML, Lundgreen A, Mullany LE, Penney RB, Wolff RK. Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality. Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014. PMID: 24959314; PMCID: PMC4065398.
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Effectiveness and Usability of Bioinformatics Tools to Analyze Pathways Associated with miRNA Expression.

Cancer informatics

Mullany LE, Wolff RK, Slattery ML.
PMID: 26560461
Cancer Inform. 2015 Oct 29;14:121-30. doi: 10.4137/CIN.S32716. eCollection 2015.

MiRNAs are small, nonprotein-coding RNA molecules involved in gene regulation. While bioinformatics help guide miRNA research, it is less clear how they perform when studying biological pathways. We used 13 criteria to evaluate effectiveness and usability of existing bioinformatics...

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Mullany LE, Wolff RK, Slattery ML. Effectiveness and Usability of Bioinformatics Tools to Analyze Pathways Associated with miRNA Expression. Cancer Inform. 2015;14:121-30doi: 10.4137/CIN.S32716.
Mullany, L. E., Wolff, R. K., & Slattery, M. L. (2015). Effectiveness and Usability of Bioinformatics Tools to Analyze Pathways Associated with miRNA Expression. Cancer informatics, 14121-30. https://doi.org/10.4137/CIN.S32716
Mullany, Lila E, et al. "Effectiveness and Usability of Bioinformatics Tools to Analyze Pathways Associated with miRNA Expression." Cancer informatics vol. 14 (2015): 121-30. doi: https://doi.org/10.4137/CIN.S32716
Mullany LE, Wolff RK, Slattery ML. Effectiveness and Usability of Bioinformatics Tools to Analyze Pathways Associated with miRNA Expression. Cancer Inform. 2015 Oct 29;14:121-30. doi: 10.4137/CIN.S32716. eCollection 2015. PMID: 26560461; PMCID: PMC4629629.
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Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.

International journal of molecular epidemiology and genetics

Curtin K, Ulrich CM, Samowitz WS, Wolff RK, Duggan DJ, Makar KW, Caan BJ, Slattery ML.
PMID: 21537397
Int J Mol Epidemiol Genet. 2011 Jan 01;2(1):1-8. Epub 2010 Nov 05.

We examined candidate polymorphisms in genes involved in the folate-mediated, one-carbon metabolism pathway, DNMT1 1311V, MTHFD1 R134K and R653Q, MTHFR R594Q, MTR D919G, MTRR H595Y and I22M, SHMT1 L474F, SLC19A1 H27R, and TDG G199S, and associations with rectal tumor...

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Curtin K, Ulrich CM, Samowitz WS, et al. Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. Int J Mol Epidemiol Genet. 2010;2(1):1-8
Curtin, K., Ulrich, C. M., Samowitz, W. S., Wolff, R. K., Duggan, D. J., Makar, K. W., Caan, B. J., & Slattery, M. L. (2011). Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. International journal of molecular epidemiology and genetics, 2(1), 1-8.
Curtin, Karen, et al. "Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations." International journal of molecular epidemiology and genetics vol. 2,1 (2011): 1-8.
Curtin K, Ulrich CM, Samowitz WS, Wolff RK, Duggan DJ, Makar KW, Caan BJ, Slattery ML. Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. Int J Mol Epidemiol Genet. 2011 Jan 01;2(1):1-8. Epub 2010 Nov 05. PMID: 21537397; PMCID: PMC3077233.
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CpG island methylation in colorectal cancer: past, present and future.

Pathology research international

Curtin K, Slattery ML, Samowitz WS.
PMID: 21559209
Patholog Res Int. 2011 Apr 12;2011:902674. doi: 10.4061/2011/902674.

The concept of a CpG island methylator phenotype, or CIMP, quickly became the focus of several colorectal cancer studies describing its clinical and pathological features after its introduction in 1999 by Toyota and colleagues. Further characterization of CIMP in...

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Curtin K, Slattery ML, Samowitz WS. CpG island methylation in colorectal cancer: past, present and future. Patholog Res Int. 2011;2011:902674doi: 10.4061/2011/902674.
Curtin, K., Slattery, M. L., & Samowitz, W. S. (2011). CpG island methylation in colorectal cancer: past, present and future. Pathology research international, 2011902674. https://doi.org/10.4061/2011/902674
Curtin, Karen, et al. "CpG island methylation in colorectal cancer: past, present and future." Pathology research international vol. 2011 (2011): 902674. doi: https://doi.org/10.4061/2011/902674
Curtin K, Slattery ML, Samowitz WS. CpG island methylation in colorectal cancer: past, present and future. Patholog Res Int. 2011 Apr 12;2011:902674. doi: 10.4061/2011/902674. PMID: 21559209; PMCID: PMC3090226.
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Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue.

Pharmacogenomics and personalized medicine

Penney RB, Lundgreen A, Yao-Borengasser A, Koroth-Edavana V, Williams S, Wolff R, Slattery ML, Kadlubar S.
PMID: 24101876
Pharmgenomics Pers Med. 2013 Sep 09;6:99-103. doi: 10.2147/PGPM.S49199. eCollection 2013.

There are a number of in silico programs that use algorithms and external web sources to predict the effect of single nucleotide polymorphisms (SNPs). While many of these programs have been shown to predict accurately the effect of SNPs...

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Penney RB, Lundgreen A, Yao-Borengasser A, et al. Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue. Pharmgenomics Pers Med. 2013;6:99-103doi: 10.2147/PGPM.S49199.
Penney, R. B., Lundgreen, A., Yao-Borengasser, A., Koroth-Edavana, V., Williams, S., Wolff, R., Slattery, M. L., & Kadlubar, S. (2013). Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue. Pharmacogenomics and personalized medicine, 699-103. https://doi.org/10.2147/PGPM.S49199
Penney, Rosalind B, et al. "Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue." Pharmacogenomics and personalized medicine vol. 6 (2013): 99-103. doi: https://doi.org/10.2147/PGPM.S49199
Penney RB, Lundgreen A, Yao-Borengasser A, Koroth-Edavana V, Williams S, Wolff R, Slattery ML, Kadlubar S. Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue. Pharmgenomics Pers Med. 2013 Sep 09;6:99-103. doi: 10.2147/PGPM.S49199. eCollection 2013. PMID: 24101876; PMCID: PMC3791675.
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Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U.
PMID: 32651213
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10.

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAID) is associated with lower risk of colorectal cancer. Genome-wide interaction analysis on single variants (G × E) has identified several SNPs that may interact with NSAIDs to confer colorectal cancer risk,...

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Wang X, Su YR, Petersen PS, et al. Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020;29(9):1800-1808doi: 10.1158/1055-9965.EPI-19-1018.
Wang, X., Su, Y. R., Petersen, P. S., Bien, S., Schmit, S. L., Drew, D. A., Albanes, D., Berndt, S. I., Brenner, H., Campbell, P. T., Casey, G., Chang-Claude, J., Gallinger, S. J., Gruber, S. B., Haile, R. W., Harrison, T. A., Hoffmeister, M., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Li, L., Lin, Y., Lindor, N. M., Marchand, L. L., Martin, V., Milne, R., Maclnnis, R., Moreno, V., Nan, H., Newcomb, P. A., Potter, J. D., Rennert, G., Rennert, H., Slattery, M. L., Thibodeau, S. N., Weinstein, S. J., Woods, M. O., Chan, A. T., White, E., Hsu, L., & Peters, U. (2020). Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29(9), 1800-1808. https://doi.org/10.1158/1055-9965.EPI-19-1018
Wang, Xiaoliang, et al. "Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 29,9 (2020): 1800-1808. doi: https://doi.org/10.1158/1055-9965.EPI-19-1018
Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U. Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10. PMID: 32651213; PMCID: PMC7556991.
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Tumor necrosis factor-related genes and colon and rectal cancer.

International journal of molecular epidemiology and genetics

Slattery ML, Lundgreen A, Bondurant KL, Wolff RK.
PMID: 22199996
Int J Mol Epidemiol Genet. 2011;2(4):328-38. Epub 2011 Oct 20.

Tumor necrosis factor-α (TNF) is a promoter of inflammation. Genes in the TNF pathway include tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNF receptor-associated factor 2 (TRAF2), mitogen activated protein kinase 8 (MAPK8), 14 (MAPK14), and mitogen activated...

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Slattery ML, Lundgreen A, Bondurant KL, et al. Tumor necrosis factor-related genes and colon and rectal cancer. Int J Mol Epidemiol Genet. 2011;2(4):328-38
Slattery, M. L., Lundgreen, A., Bondurant, K. L., & Wolff, R. K. (2011). Tumor necrosis factor-related genes and colon and rectal cancer. International journal of molecular epidemiology and genetics, 2(4), 328-38.
Slattery, Martha L, et al. "Tumor necrosis factor-related genes and colon and rectal cancer." International journal of molecular epidemiology and genetics vol. 2,4 (2011): 328-38.
Slattery ML, Lundgreen A, Bondurant KL, Wolff RK. Tumor necrosis factor-related genes and colon and rectal cancer. Int J Mol Epidemiol Genet. 2011;2(4):328-38. Epub 2011 Oct 20. PMID: 22199996; PMCID: PMC3243449.
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Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality.

International journal of molecular epidemiology and genetics

Slattery ML, Pellatt DF, Wolff RK, Lundgreen A.
PMID: 27186328
Int J Mol Epidemiol Genet. 2016 Mar 23;7(1):45-57. eCollection 2016.

Genetic and environmental factors have been shown to work together to alter cancer risk. In this study we evaluate previously identified gene and lifestyle interactions in a candidate pathway that were associated with colon cancer risk to see if...

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Slattery ML, Pellatt DF, Wolff RK, et al. Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality. Int J Mol Epidemiol Genet. 2016;7(1):45-57
Slattery, M. L., Pellatt, D. F., Wolff, R. K., & Lundgreen, A. (2016). Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality. International journal of molecular epidemiology and genetics, 7(1), 45-57.
Slattery, Martha L, et al. "Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality." International journal of molecular epidemiology and genetics vol. 7,1 (2016): 45-57.
Slattery ML, Pellatt DF, Wolff RK, Lundgreen A. Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality. Int J Mol Epidemiol Genet. 2016 Mar 23;7(1):45-57. eCollection 2016. PMID: 27186328; PMCID: PMC4858616.
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An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis.

Cancer informatics

Slattery ML, Herrick JS, Stevens JR, Wolff RK, Mullany LE.
PMID: 28690395
Cancer Inform. 2017 Jun 23;16:1176935117716405. doi: 10.1177/1176935117716405. eCollection 2017.

BACKGROUND: Determination of functional pathways regulated by microRNAs (miRNAs), while an essential step in developing therapeutics, is challenging. Some miRNAs have been studied extensively; others have limited information. In this study, we focus on 254 miRNAs previously identified as...

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Slattery ML, Herrick JS, Stevens JR, et al. An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis. Cancer Inform. 2017;16:1176935117716405doi: 10.1177/1176935117716405.
Slattery, M. L., Herrick, J. S., Stevens, J. R., Wolff, R. K., & Mullany, L. E. (2017). An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis. Cancer informatics, 161176935117716405. https://doi.org/10.1177/1176935117716405
Slattery, Martha L, et al. "An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis." Cancer informatics vol. 16 (2017): 1176935117716405. doi: https://doi.org/10.1177/1176935117716405
Slattery ML, Herrick JS, Stevens JR, Wolff RK, Mullany LE. An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis. Cancer Inform. 2017 Jun 23;16:1176935117716405. doi: 10.1177/1176935117716405. eCollection 2017. PMID: 28690395; PMCID: PMC5484592.
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Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer.

Oncotarget

Slattery ML, Pellatt AJ, Lee FY, Herrick JS, Samowitz WS, Stevens JR, Wolff RK, Mullany LE.
PMID: 29137387
Oncotarget. 2017 Aug 03;8(48):83845-83859. doi: 10.18632/oncotarget.19863. eCollection 2017 Oct 13.

Half of miRNAs expressed in colorectal tissue are expressed < 50% of the population. Many infrequently expressed miRNAs have low levels of expression. We hypothesize that less frequently expressed miRNAs, when expressed at higher levels, influence both disease stage...

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Slattery ML, Pellatt AJ, Lee FY, et al. Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer. Oncotarget. 2017;8(48):83845-83859doi: 10.18632/oncotarget.19863.
Slattery, M. L., Pellatt, A. J., Lee, F. Y., Herrick, J. S., Samowitz, W. S., Stevens, J. R., Wolff, R. K., & Mullany, L. E. (2017). Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer. Oncotarget, 8(48), 83845-83859. https://doi.org/10.18632/oncotarget.19863
Slattery, Martha L, et al. "Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer." Oncotarget vol. 8,48 (2017): 83845-83859. doi: https://doi.org/10.18632/oncotarget.19863
Slattery ML, Pellatt AJ, Lee FY, Herrick JS, Samowitz WS, Stevens JR, Wolff RK, Mullany LE. Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer. Oncotarget. 2017 Aug 03;8(48):83845-83859. doi: 10.18632/oncotarget.19863. eCollection 2017 Oct 13. PMID: 29137387; PMCID: PMC5663559.
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PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer.

Genes & nutrition

Habermann N, Ulrich CM, Lundgreen A, Makar KW, Poole EM, Caan B, Kulmacz R, Whitton J, Galbraith R, Potter JD, Slattery ML.
PMID: 22678777
Genes Nutr. 2013 Jan;8(1):115-26. doi: 10.1007/s12263-012-0302-x. Epub 2012 Jun 08.

Dietary polyunsaturated fatty acids (PUFAs) can be converted to prostaglandins and leukotrienes. Oxygenation of omega-6 PUFAs generally results in the production of pro-inflammatory mediators, whereas oxygenated products of omega-3 (n-3) PUFAs generally have lower inflammatory activity. We hypothesize that...

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Habermann N, Ulrich CM, Lundgreen A, et al. PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer. Genes Nutr. 2012;8(1):115-26doi: 10.1007/s12263-012-0302-x.
Habermann, N., Ulrich, C. M., Lundgreen, A., Makar, K. W., Poole, E. M., Caan, B., Kulmacz, R., Whitton, J., Galbraith, R., Potter, J. D., & Slattery, M. L. (2013). PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer. Genes & nutrition, 8(1), 115-26. https://doi.org/10.1007/s12263-012-0302-x
Habermann, Nina, et al. "PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer." Genes & nutrition vol. 8,1 (2013): 115-26. doi: https://doi.org/10.1007/s12263-012-0302-x
Habermann N, Ulrich CM, Lundgreen A, Makar KW, Poole EM, Caan B, Kulmacz R, Whitton J, Galbraith R, Potter JD, Slattery ML. PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer. Genes Nutr. 2013 Jan;8(1):115-26. doi: 10.1007/s12263-012-0302-x. Epub 2012 Jun 08. PMID: 22678777; PMCID: PMC3534991.
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Showing 1 to 12 of 20 entries