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Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study.

Frontiers in oncology

Heck JE, Moore LE, Lee YC, McKay JD, Hung RJ, Karami S, Gaborieau V, Szeszenia-Dabrowska N, Zaridze DG, Mukeriya A, Mates D, Foretova L, Janout V, Kollárová H, Bencko V, Rothman N, Brennan P, Chow WH, Boffetta P.
PMID: 22645715
Front Oncol. 2012 Feb 20;2:16. doi: 10.3389/fonc.2012.00016. eCollection 2012.

BACKGROUND: The countries of Central and Eastern Europe have among the highest worldwide rates of renal cell cancer (RCC). Few studies have examined whether genetic variation in xenobiotic metabolic pathway genes may modify risk for this cancer.METHODS: The Central...

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data.

Genomics data

Dunkhase E, Ludwig KU, Knapp M, Skibola CF, Figueiredo JC, Hosking FJ, Ellinghaus E, Landi MT, Ma H, Nakagawa H, Kim JW, Han J, Yang P, Böhmer AC, Mattheisen M, Nöthen MM, Mangold E.
PMID: 27630819
Genom Data. 2016 Aug 26;10:22-9. doi: 10.1016/j.gdata.2016.08.017. eCollection 2016 Dec.

Previous research suggests a genetic overlap between nonsyndromic cleft lip with or without cleft palate (NSCL/P) and cancer. The aim of the present study was to identify common genetic risk loci for NSCL/P and cancer entities that have been...

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