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The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET.

Cellular logistics

Lachmann J, Glaubke E, Moore PS, Ungermann C.
PMID: 25750764
Cell Logist. 2014 Oct 02;4(4):e970840. doi: 10.4161/21592780.2014.970840. eCollection 2014.

Membrane fusion in the endocytic pathway is mediated by a protein machinery consistent of Rab GTPases, tethering factors and SNAREs. In yeast, the endosomal CORVET and lysosomal HOPS tethering complexes share 4 of their 6 subunits. The 2 additional...

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Lachmann J, Glaubke E, Moore PS, et al. The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET. Cell Logist. 2014;4(4):e970840doi: 10.4161/21592780.2014.970840.
Lachmann, J., Glaubke, E., Moore, P. S., & Ungermann, C. (2014). The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET. Cellular logistics, 4(4), e970840. https://doi.org/10.4161/21592780.2014.970840
Lachmann, Jens, et al. "The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET." Cellular logistics vol. 4,4 (2014): e970840. doi: https://doi.org/10.4161/21592780.2014.970840
Lachmann J, Glaubke E, Moore PS, Ungermann C. The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET. Cell Logist. 2014 Oct 02;4(4):e970840. doi: 10.4161/21592780.2014.970840. eCollection 2014. PMID: 25750764; PMCID: PMC4325178.
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Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay.

mSphere

Rigatti LH, Toptan T, Newsome JT, Moore PS, Chang Y.
PMID: 28028546
mSphere. 2016 Dec 21;1(6). doi: 10.1128/mSphere.00334-16. eCollection 2016.

Polyomaviruses (PyVs) are known to infect a wide range of vertebrates and invertebrates and are associated with a broad spectrum of diseases, including cancers, particularly in immune-suppressed hosts. A novel polyomavirus, designated rat polyomavirus 2 (RatPyV2), was identified from...

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Rigatti LH, Toptan T, Newsome JT, et al. Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay. mSphere. 2016;1(6)doi: 10.1128/mSphere.00334-16.
Rigatti, L. H., Toptan, T., Newsome, J. T., Moore, P. S., & Chang, Y. (2016). Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay. mSphere, 1(6), . https://doi.org/10.1128/mSphere.00334-16
Rigatti, Lora H, et al. "Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay." mSphere vol. 1,6 (2016). doi: https://doi.org/10.1128/mSphere.00334-16
Rigatti LH, Toptan T, Newsome JT, Moore PS, Chang Y. Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay. mSphere. 2016 Dec 21;1(6). doi: 10.1128/mSphere.00334-16. eCollection 2016. PMID: 28028546; PMCID: PMC5177731.
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Survey for human polyomaviruses in cancer.

JCI insight

Toptan T, Yousem SA, Ho J, Matsushima Y, Stabile LP, Fernández-Figueras MT, Bhargava R, Ryo A, Moore PS, Chang Y.
PMID: 27034991
JCI Insight. 2016 Feb;1(2). doi: 10.1172/jci.insight.85562. Epub 2016 Feb 25.

Over the past 8 years, the discovery of 11 new human polyomaviruses (HPyVs) has revived interest in this DNA tumor virus family. Although HPyV infection is widespread and largely asymptomatic, one of these HPyVs, Merkel cell polyomavirus (MCV), is...

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Toptan T, Yousem SA, Ho J, et al. Survey for human polyomaviruses in cancer. JCI Insight. 2016;1(2)doi: 10.1172/jci.insight.85562.
Toptan, T., Yousem, S. A., Ho, J., Matsushima, Y., Stabile, L. P., Fernández-Figueras, M. T., Bhargava, R., Ryo, A., Moore, P. S., & Chang, Y. (2016). Survey for human polyomaviruses in cancer. JCI insight, 1(2), . https://doi.org/10.1172/jci.insight.85562
Toptan, Tuna, et al. "Survey for human polyomaviruses in cancer." JCI insight vol. 1,2 (2016). doi: https://doi.org/10.1172/jci.insight.85562
Toptan T, Yousem SA, Ho J, Matsushima Y, Stabile LP, Fernández-Figueras MT, Bhargava R, Ryo A, Moore PS, Chang Y. Survey for human polyomaviruses in cancer. JCI Insight. 2016 Feb;1(2). doi: 10.1172/jci.insight.85562. Epub 2016 Feb 25. PMID: 27034991; PMCID: PMC4811373.
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Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1.

Frontiers in microbiology

Velásquez C, Amako Y, Harold A, Toptan T, Chang Y, Shuda M.
PMID: 29696010
Front Microbiol. 2018 Apr 11;9:713. doi: 10.3389/fmicb.2018.00713. eCollection 2018.

Merkel cell polyomavirus (MCV) plays a causal role in ∼80% of Merkel cell carcinomas (MCC). MCV is clonally integrated into the MCC tumor genome, which results in persistent expression of large T (LT) and small T (sT) antigen oncoproteins...

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Velásquez C, Amako Y, Harold A, et al. Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1. Front Microbiol. 2018;9:713doi: 10.3389/fmicb.2018.00713.
Velásquez, C., Amako, Y., Harold, A., Toptan, T., Chang, Y., & Shuda, M. (2018). Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1. Frontiers in microbiology, 9713. https://doi.org/10.3389/fmicb.2018.00713
Velásquez, Celestino, et al. "Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1." Frontiers in microbiology vol. 9 (2018): 713. doi: https://doi.org/10.3389/fmicb.2018.00713
Velásquez C, Amako Y, Harold A, Toptan T, Chang Y, Shuda M. Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1. Front Microbiol. 2018 Apr 11;9:713. doi: 10.3389/fmicb.2018.00713. eCollection 2018. PMID: 29696010; PMCID: PMC5905237.
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