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Showing 1 to 12 of 27 entries
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Linking pesticides and human health: a geographic information system (GIS) and Landsat remote sensing method to estimate agricultural pesticide exposure.

Applied geography (Sevenoaks, England)

VoPham T, Wilson JP, Ruddell D, Rashed T, Brooks MM, Yuan JM, Talbott EO, Chang CH, Weissfeld JL.
PMID: 28867851
Appl Geogr. 2015 Aug;62:171-181. doi: 10.1016/j.apgeog.2015.04.009. Epub 2015 May 18.

Accurate pesticide exposure estimation is integral to epidemiologic studies elucidating the role of pesticides in human health. Humans can be exposed to pesticides via residential proximity to agricultural pesticide applications (drift). We present an improved geographic information system (GIS)...

Serum IL27 in Relation to Risk of Hepatocellular Carcinoma in Two Nested Case-Control Studies.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Yuan JM, Wang Y, Wang R, Luu HN, Adams-Haduch J, Koh WP, Gao YT, Behari J, Lotze MT.
PMID: 33203693
Cancer Epidemiol Biomarkers Prev. 2021 Feb;30(2):388-395. doi: 10.1158/1055-9965.EPI-20-1081. Epub 2020 Nov 17.

BACKGROUND: IL27 mRNA is highly enriched in the tissue of hepatocellular carcinoma. Overexpression of IL27 gene has been found to increase T-cell expression of inhibitory receptors, an immunosuppressive feature in tumor microenvironment, that promotes the development of hepatocellular carcinoma.METHODS:...

Polygenic Risk Scores in a Prospective Parkinson's Disease Cohort.

Movement disorders : official journal of the Movement Disorder Society

Sia MW, Foo JN, Saffari SE, Wong AS, Khor CC, Yuan JM, Tan EK, Koh WP, Tan LC.
PMID: 34402545
Mov Disord. 2021 Dec;36(12):2936-2940. doi: 10.1002/mds.28761. Epub 2021 Aug 17.

BACKGROUND: Ethnic-specific genetic risk assessment framework for Parkinson's disease (PD) is lacking for the Asian population.OBJECTIVE: We investigated the association of a polygenic risk score (PRS) with PD incidence in a population-based Asian prospective cohort.METHODS: Genetic, dietary, and lifestyle...

Composite Score of Healthy Lifestyle Factors and Risk of Hepatocellular Carcinoma: Findings from a Prospective Cohort Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Luu HN, Behari J, Goh GB, Wang R, Jin A, Thomas CE, Clemente JC, Odegaard AO, Koh WP, Yuan JM.
PMID: 33187965
Cancer Epidemiol Biomarkers Prev. 2021 Feb;30(2):380-387. doi: 10.1158/1055-9965.EPI-20-1201. Epub 2020 Nov 13.

BACKGROUND: While the associations between individual lifestyle factors and risk of hepatocellular carcinoma (HCC) have been described previously, their combined impact on HCC risk is unknown.METHODS: The association of a composite score of healthy lifestyle factors, including body mass...

Composite Score of Healthy Lifestyle Factors and the Risk of Pancreatic Cancer in a Prospective Cohort Study.

Cancer prevention research (Philadelphia, Pa.)

Luu HN, Paragomi P, Wang R, Jin A, Brand RE, Koh WP, Yuan JM.
PMID: 34642175
Cancer Prev Res (Phila). 2022 Jan;15(1):29-36. doi: 10.1158/1940-6207.CAPR-21-0205. Epub 2021 Oct 12.

While the associations between individual lifestyle factors and risk of pancreatic cancer were studied extensively, their combined impact has not been examined. We evaluated the association of a composite score of healthy lifestyle factors, including body mass index, cigarette...

Reduction in total and major cause-specific mortality from tobacco smoking cessation: a pooled analysis of 16 population-based cohort studies in Asia.

International journal of epidemiology

Yang JJ, Yu D, Shu XO, Wen W, Rahman S, Abe S, Saito E, Gupta PC, He J, Tsugane S, Gao YT, Yuan JM, Koh WP, Sadakane A, Tomata Y, Tsuji I, Sugawara Y, Matsuo K, Ahn YO, Park SK, Chen Y, Inoue M, Kang D, Zheng W.
PMID: 34009320
Int J Epidemiol. 2021 Feb 05; doi: 10.1093/ije/dyab087. Epub 2021 Feb 05.

BACKGROUND: Little is known about the time course of mortality reduction following smoking cessation in Asians who have smoking behaviours distinct from their Western counterparts. We evaluated the level of reduction in all-cause, cardiovascular disease (CVD) and lung cancer...

One-carbon metabolism nutrient status and plasma S-adenosylmethionine concentrations in middle-aged and older Chinese in Singapore.

International journal of molecular epidemiology and genetics

Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh WP, Yuan JM.
PMID: 22724053
Int J Mol Epidemiol Genet. 2012;3(2):160-73. Epub 2012 May 15.

S-adenosylmethionine (SAM) is a primary methyl donor for the methylation of many molecules including DNA. DNA methylation is believed to play an important role in functions of cells and genes. Dietary, genetic and metabolic factors that influence systematic SAM...

A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.

Genes & nutrition

Dorajoo R, Sun Y, Han Y, Ke T, Burger A, Chang X, Low HQ, Guan W, Lemaitre RN, Khor CC, Yuan JM, Koh WP, Ong CN, Tai ES, Liu J, van Dam RM, Heng CK, Friedlander Y.
PMID: 26584805
Genes Nutr. 2015 Nov;10(6):53. doi: 10.1007/s12263-015-0502-2. Epub 2015 Nov 19.

Polyunsaturated fatty acids (PUFAs) have a major impact on human health. Recent genome-wide association studies (GWAS) have identified several genetic loci that are associated with plasma levels of n-3 and n-6 PUFAs in primarily subjects of European ancestry. However,...

Smoking, life expectancy, and chronic disease in South Korea, Singapore, and the United States: A microsimulation model.

Health economics

Kim D, Chen C, Tysinger B, Park S, Chong MZ, Wang L, Zhao M, Yuan JM, Koh WP, Yoong J, Bhattacharya J, Eggleston K.
PMID: 31802569
Health Econ. 2021 Nov;30:92-104. doi: 10.1002/hec.3978. Epub 2019 Dec 04.

The substantial social and economic burden attributable to smoking is well-known, with heavy smokers at higher risk of chronic disease and premature mortality than light smokers and nonsmokers. In aging societies with high rates of male smoking such as...

Smoking, life expectancy, and chronic disease in South Korea, Singapore, and the United States: A microsimulation model.

Health economics

Kim D, Chen C, Tysinger B, Park S, Chong MZ, Wang L, Zhao M, Yuan JM, Koh WP, Yoong J, Bhattacharya J, Eggleston K.
PMID: 31802569
Health Econ. 2021 Nov;30:92-104. doi: 10.1002/hec.3978. Epub 2019 Dec 04.

The substantial social and economic burden attributable to smoking is well-known, with heavy smokers at higher risk of chronic disease and premature mortality than light smokers and nonsmokers. In aging societies with high rates of male smoking such as...

Diabetes and other vascular risk factors in association with the risk of lower extremity amputation in chronic limb-threatening ischemia: a prospective cohort study.

Cardiovascular diabetology

Ying AF, Tang TY, Jin A, Chong TT, Hausenloy DJ, Koh WP.
PMID: 34998400
Cardiovasc Diabetol. 2022 Jan 08;21(1):7. doi: 10.1186/s12933-021-01441-0.

BACKGROUND: Patients with diabetes are at increased risk of developing chronic limb-threatening ischemia (CLTI) due to peripheral arterial disease, and this often results in lower extremity amputation (LEA). Little is known of the interaction between diabetes and other vascular...

Reduction in total and major cause-specific mortality from tobacco smoking cessation: a pooled analysis of 16 population-based cohort studies in Asia.

International journal of epidemiology

Yang JJ, Yu D, Shu XO, Wen W, Rahman S, Abe S, Saito E, Gupta PC, He J, Tsugane S, Gao YT, Yuan JM, Koh WP, Sadakane A, Tomata Y, Tsuji I, Sugawara Y, Matsuo K, Ahn YO, Park SK, Chen Y, Inoue M, Kang D, Zheng W.
PMID: 34009320
Int J Epidemiol. 2021 Feb 05; doi: 10.1093/ije/dyab087. Epub 2021 Feb 05.

BACKGROUND: Little is known about the time course of mortality reduction following smoking cessation in Asians who have smoking behaviours distinct from their Western counterparts. We evaluated the level of reduction in all-cause, cardiovascular disease (CVD) and lung cancer...

Showing 1 to 12 of 27 entries