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Use of admixture and association for detection of quantitative trait loci in the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples (T2D-GENES) study.

BMC proceedings

Yorgov D, Edwards KL, Santorico SA.
PMID: 25519335
BMC Proc. 2014 Jun 17;8:S6. doi: 10.1186/1753-6561-8-S1-S6. eCollection 2014.

Admixture mapping and association testing have been successfully applied to the detection of genes for complex diseases. Methods have also been developed to combine these approaches. As an initial step to determine the feasibility of combining admixture and association...

What are our AIMs? Interdisciplinary Perspectives on the Use of Ancestry Estimation in Disease Research.

AJOB primary research

Yu JH, Taylor JS, Edwards KL, Fullerton SM.
PMID: 25419472
AJOB Prim Res. 2012;3(4):87-97. doi: 10.1080/21507716.2012.717339.

BACKGROUND: Ancestry estimation serves as a tool to identify genetic contributions to disease but may contribute to racial discrimination and stigmatization. We sought to understand user perspectives on the benefits and harms of ancestry estimation to inform research practice...

Showing 1 to 2 of 2 entries