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Nuclear receptors: from molecular mechanisms to therapeutics.

Essays in biochemistry

Frigo DE, Bondesson M, Williams C.
PMID: 34825698
Essays Biochem. 2021 Dec 17;65(6):847-856. doi: 10.1042/EBC20210020.

Nuclear receptors are classically defined as ligand-activated transcription factors that regulate key functions in reproduction, development, and physiology. Humans have 48 nuclear receptors, which when dysregulated are often linked to diseases. Because most nuclear receptors can be selectively activated...

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Frigo DE, Bondesson M, Williams C. Nuclear receptors: from molecular mechanisms to therapeutics. Essays Biochem. 2021;65(6):847-856doi: 10.1042/EBC20210020.
Frigo, D. E., Bondesson, M., & Williams, C. (2021). Nuclear receptors: from molecular mechanisms to therapeutics. Essays in biochemistry, 65(6), 847-856. https://doi.org/10.1042/EBC20210020
Frigo, Daniel E, et al. "Nuclear receptors: from molecular mechanisms to therapeutics." Essays in biochemistry vol. 65,6 (2021): 847-856. doi: https://doi.org/10.1042/EBC20210020
Frigo DE, Bondesson M, Williams C. Nuclear receptors: from molecular mechanisms to therapeutics. Essays Biochem. 2021 Dec 17;65(6):847-856. doi: 10.1042/EBC20210020. PMID: 34825698; PMCID: PMC8628184.
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A simple quantitative PCR assay to determine TRAMP transgene zygosity.

Prostate cancer and prostatic diseases

Chen R, Liang X, Murray MM, Karasik E, Han JJ, Zhu M, Foster BA, Frigo DE, Wang G.
PMID: 32895469
Prostate Cancer Prostatic Dis. 2021 Jun;24(2):358-361. doi: 10.1038/s41391-020-00282-4. Epub 2020 Sep 07.

BACKGROUND: The TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model remains one of the most widely used transgenic mouse models of prostate cancer. This is due to its ability to recapitulate with ~100% penetrance multiple aspects of the human...

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Chen R, Liang X, Murray MM, et al. A simple quantitative PCR assay to determine TRAMP transgene zygosity. Prostate Cancer Prostatic Dis. 2020;24(2):358-361doi: 10.1038/s41391-020-00282-4.
Chen, R., Liang, X., Murray, M. M., Karasik, E., Han, J. J., Zhu, M., Foster, B. A., Frigo, D. E., & Wang, G. (2021). A simple quantitative PCR assay to determine TRAMP transgene zygosity. Prostate cancer and prostatic diseases, 24(2), 358-361. https://doi.org/10.1038/s41391-020-00282-4
Chen, Ruidong, et al. "A simple quantitative PCR assay to determine TRAMP transgene zygosity." Prostate cancer and prostatic diseases vol. 24,2 (2021): 358-361. doi: https://doi.org/10.1038/s41391-020-00282-4
Chen R, Liang X, Murray MM, Karasik E, Han JJ, Zhu M, Foster BA, Frigo DE, Wang G. A simple quantitative PCR assay to determine TRAMP transgene zygosity. Prostate Cancer Prostatic Dis. 2021 Jun;24(2):358-361. doi: 10.1038/s41391-020-00282-4. Epub 2020 Sep 07. PMID: 32895469; PMCID: PMC7936990.
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