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New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance.

Precision clinical medicine

Karin M.
PMID: 30687560
Precis Clin Med. 2018 Jun;1(1):21-28. doi: 10.1093/pcmedi/pby005. Epub 2018 Jun 04.

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. HCC initiates as a consequence of chronic liver damage and inflammation caused by hepatitis B and C virus infections, excessive alcohol consumption, or non-alcoholic fatty liver...

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Karin M. New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance. Precis Clin Med. 2018;1(1):21-28doi: 10.1093/pcmedi/pby005.
Karin, M. (2018). New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance. Precision clinical medicine, 1(1), 21-28. https://doi.org/10.1093/pcmedi/pby005
Karin, Michael. "New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance." Precision clinical medicine vol. 1,1 (2018): 21-28. doi: https://doi.org/10.1093/pcmedi/pby005
Karin M. New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance. Precis Clin Med. 2018 Jun;1(1):21-28. doi: 10.1093/pcmedi/pby005. Epub 2018 Jun 04. PMID: 30687560; PMCID: PMC6333043.
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"Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis.

Cell metabolism

Febbraio MA, Karin M.
PMID: 34619076
Cell Metab. 2021 Dec 07;33(12):2316-2328. doi: 10.1016/j.cmet.2021.09.004. Epub 2021 Oct 06.

Glucose and fructose are closely related simple sugars, but fructose has been associated more closely with metabolic disease. Until the 1960s, the major dietary source of fructose was fruit, but subsequently, high-fructose corn syrup (HFCS) became a dominant component...

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Febbraio MA, Karin M. "Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. Cell Metab. 2021;33(12):2316-2328doi: 10.1016/j.cmet.2021.09.004.
Febbraio, M. A., & Karin, M. (2021). "Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. Cell metabolism, 33(12), 2316-2328. https://doi.org/10.1016/j.cmet.2021.09.004
Febbraio, Mark A, and Karin, Michael. ""Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis." Cell metabolism vol. 33,12 (2021): 2316-2328. doi: https://doi.org/10.1016/j.cmet.2021.09.004
Febbraio MA, Karin M. "Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. Cell Metab. 2021 Dec 07;33(12):2316-2328. doi: 10.1016/j.cmet.2021.09.004. Epub 2021 Oct 06. PMID: 34619076; PMCID: PMC8665123.
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An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis.

STAR protocols

Kasashima H, Duran A, Cid-Diaz T, Kudo Y, Diaz-Meco MT, Moscat J.
PMID: 33377079
STAR Protoc. 2020 Nov 20;1(3):100185. doi: 10.1016/j.xpro.2020.100185. eCollection 2020 Dec 18.

This protocol provides the steps required for a mouse liver orthotopic implantation model. The reliable pre-clinical animal models that have similar characteristics to hepatocellular carcinoma (HCC) are a powerful tool to unveil the mechanisms controlling tumor initiation and progression....

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Kasashima H, Duran A, Cid-Diaz T, et al. An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis. STAR Protoc. 2020;1(3):100185doi: 10.1016/j.xpro.2020.100185.
Kasashima, H., Duran, A., Cid-Diaz, T., Kudo, Y., Diaz-Meco, M. T., & Moscat, J. (2020). An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis. STAR protocols, 1(3), 100185. https://doi.org/10.1016/j.xpro.2020.100185
Kasashima, Hiroaki, et al. "An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis." STAR protocols vol. 1,3 (2020): 100185. doi: https://doi.org/10.1016/j.xpro.2020.100185
Kasashima H, Duran A, Cid-Diaz T, Kudo Y, Diaz-Meco MT, Moscat J. An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis. STAR Protoc. 2020 Nov 20;1(3):100185. doi: 10.1016/j.xpro.2020.100185. eCollection 2020 Dec 18. PMID: 33377079; PMCID: PMC7757567.
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The neglected brothers come of age: B cells and cancer.

Seminars in immunology

Shalapour S, Karin M.
PMID: 34215491
Semin Immunol. 2021 Feb;52:101479. doi: 10.1016/j.smim.2021.101479. Epub 2021 Jun 29.

The opposing roles of innate and adaptive immune cells in suppressing or supporting cancer initiation, progression, metastasis and response to therapy has been long debated. The mechanisms by which different monocyte and T cell subtypes affect and modulate cancer...

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Shalapour S, Karin M. The neglected brothers come of age: B cells and cancer. Semin Immunol. 2021;52:101479doi: 10.1016/j.smim.2021.101479.
Shalapour, S., & Karin, M. (2021). The neglected brothers come of age: B cells and cancer. Seminars in immunology, 52101479. https://doi.org/10.1016/j.smim.2021.101479
Shalapour, Shabnam, and Karin, Michael. "The neglected brothers come of age: B cells and cancer." Seminars in immunology vol. 52 (2021): 101479. doi: https://doi.org/10.1016/j.smim.2021.101479
Shalapour S, Karin M. The neglected brothers come of age: B cells and cancer. Semin Immunol. 2021 Feb;52:101479. doi: 10.1016/j.smim.2021.101479. Epub 2021 Jun 29. PMID: 34215491; PMCID: PMC8545794.
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Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum.

STAR protocols

Kasashima H, Duran A, Cid-Diaz T, Muta Y, Kinoshita H, Batlle E, Diaz-Meco MT, Moscat J.
PMID: 33554135
STAR Protoc. 2021 Jan 22;2(1):100297. doi: 10.1016/j.xpro.2021.100297. eCollection 2021 Mar 19.

No abstract available.

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Kasashima H, Duran A, Cid-Diaz T, et al. Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum. STAR Protoc. 2021;2(1):100297doi: 10.1016/j.xpro.2021.100297.
Kasashima, H., Duran, A., Cid-Diaz, T., Muta, Y., Kinoshita, H., Batlle, E., Diaz-Meco, M. T., & Moscat, J. (2021). Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum. STAR protocols, 2(1), 100297. https://doi.org/10.1016/j.xpro.2021.100297
Kasashima, Hiroaki, et al. "Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum." STAR protocols vol. 2,1 (2021): 100297. doi: https://doi.org/10.1016/j.xpro.2021.100297
Kasashima H, Duran A, Cid-Diaz T, Muta Y, Kinoshita H, Batlle E, Diaz-Meco MT, Moscat J. Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum. STAR Protoc. 2021 Jan 22;2(1):100297. doi: 10.1016/j.xpro.2021.100297. eCollection 2021 Mar 19. PMID: 33554135; PMCID: PMC7843928.
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"Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis.

Cell metabolism

Febbraio MA, Karin M.
PMID: 34619076
Cell Metab. 2021 Dec 07;33(12):2316-2328. doi: 10.1016/j.cmet.2021.09.004. Epub 2021 Oct 06.

Glucose and fructose are closely related simple sugars, but fructose has been associated more closely with metabolic disease. Until the 1960s, the major dietary source of fructose was fruit, but subsequently, high-fructose corn syrup (HFCS) became a dominant component...

Cite
Febbraio MA, Karin M. "Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. Cell Metab. 2021;33(12):2316-2328doi: 10.1016/j.cmet.2021.09.004.
Febbraio, M. A., & Karin, M. (2021). "Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. Cell metabolism, 33(12), 2316-2328. https://doi.org/10.1016/j.cmet.2021.09.004
Febbraio, Mark A, and Karin, Michael. ""Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis." Cell metabolism vol. 33,12 (2021): 2316-2328. doi: https://doi.org/10.1016/j.cmet.2021.09.004
Febbraio MA, Karin M. "Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. Cell Metab. 2021 Dec 07;33(12):2316-2328. doi: 10.1016/j.cmet.2021.09.004. Epub 2021 Oct 06. PMID: 34619076; PMCID: PMC8665123.
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Showing 1 to 6 of 6 entries