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Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2.

European urology focus

Leo P, Chandramouli S, Farré X, Elliott R, Janowczyk A, Bera K, Fu P, Janaki N, El-Fahmawi A, Shahait M, Kim J, Lee D, Yamoah K, Rebbeck TR, Khani F, Robinson BD, Shih NNC, Feldman M, Gupta S, McKenney J, Lal P, Madabhushi A.
PMID: 33941504
Eur Urol Focus. 2021 Jul;7(4):722-732. doi: 10.1016/j.euf.2021.04.016. Epub 2021 Apr 30.

BACKGROUND: The presence of invasive cribriform adenocarcinoma (ICC), an expanse of cells containing punched-out lumina uninterrupted by stroma, in radical prostatectomy (RP) specimens has been associated with biochemical recurrence (BCR). However, ICC identification has only moderate inter-reviewer agreement.OBJECTIVE: To...

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Leo P, Chandramouli S, Farré X, et al. Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2. Eur Urol Focus. 2021;7(4):722-732doi: 10.1016/j.euf.2021.04.016.
Leo, P., Chandramouli, S., Farré, X., Elliott, R., Janowczyk, A., Bera, K., Fu, P., Janaki, N., El-Fahmawi, A., Shahait, M., Kim, J., Lee, D., Yamoah, K., Rebbeck, T. R., Khani, F., Robinson, B. D., Shih, N. N. C., Feldman, M., Gupta, S., McKenney, J., Lal, P., & Madabhushi, A. (2021). Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2. European urology focus, 7(4), 722-732. https://doi.org/10.1016/j.euf.2021.04.016
Leo, Patrick, et al. "Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2." European urology focus vol. 7,4 (2021): 722-732. doi: https://doi.org/10.1016/j.euf.2021.04.016
Leo P, Chandramouli S, Farré X, Elliott R, Janowczyk A, Bera K, Fu P, Janaki N, El-Fahmawi A, Shahait M, Kim J, Lee D, Yamoah K, Rebbeck TR, Khani F, Robinson BD, Shih NNC, Feldman M, Gupta S, McKenney J, Lal P, Madabhushi A. Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2. Eur Urol Focus. 2021 Jul;7(4):722-732. doi: 10.1016/j.euf.2021.04.016. Epub 2021 Apr 30. PMID: 33941504; PMCID: PMC8419103.
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Multi-Compartment Spatially-Derived Radiomics From Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease: Preliminary Findings.

IEEE journal of translational engineering in health and medicine

Sil Kar S, Sevgi DD, Dong V, Srivastava SK, Madabhushi A, Ehlers JP.
PMID: 34350068
IEEE J Transl Eng Health Med. 2021 Jul 12;9:1000113. doi: 10.1109/JTEHM.2021.3096378. eCollection 2021.

OBJECTIVE: Diabetic macular edema (DME) and retinal vein occlusion (RVO) are the leading causes of visual impairments across the world. Vascular endothelial growth factor (VEGF) stimulates breakdown of blood-retinal barrier that causes accumulation of fluid within macula. Anti-VEGF therapy...

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Sil Kar S, Sevgi DD, Dong V, et al. Multi-Compartment Spatially-Derived Radiomics From Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease: Preliminary Findings. IEEE J Transl Eng Health Med. 2021;9:1000113doi: 10.1109/JTEHM.2021.3096378.
Sil Kar, S., Sevgi, D. D., Dong, V., Srivastava, S. K., Madabhushi, A., & Ehlers, J. P. (2021). Multi-Compartment Spatially-Derived Radiomics From Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease: Preliminary Findings. IEEE journal of translational engineering in health and medicine, 91000113. https://doi.org/10.1109/JTEHM.2021.3096378
Sil Kar, Sudeshna, et al. "Multi-Compartment Spatially-Derived Radiomics From Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease: Preliminary Findings." IEEE journal of translational engineering in health and medicine vol. 9 (2021): 1000113. doi: https://doi.org/10.1109/JTEHM.2021.3096378
Sil Kar S, Sevgi DD, Dong V, Srivastava SK, Madabhushi A, Ehlers JP. Multi-Compartment Spatially-Derived Radiomics From Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease: Preliminary Findings. IEEE J Transl Eng Health Med. 2021 Jul 12;9:1000113. doi: 10.1109/JTEHM.2021.3096378. eCollection 2021. PMID: 34350068; PMCID: PMC8328398.
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